Patents by Inventor Lidia Cristian

Lidia Cristian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antiviral compounds and their methods of use
    Patent number: 8691808
    Abstract: The present disclosure provides compounds having affinity for the M2 proton channel, useful for the treatment of viral infections such as influenza, which are of the Formula (I): wherein R1, R2, and Y are as defined herein. Methods of preparing the compounds, pharmaceutical compositions containing the compounds, and methods of using the compounds in the treatment of viral infections such as influenza are also provided.
    Type: Grant
    Filed: May 18, 2012
    Date of Patent: April 8, 2014
    Assignee: Influmedix, Inc.
    Inventors: Jizhou Wang, Xiaodong Fan, Lidia Cristian
  • Methods of use of antiviral compounds
    Patent number: 8440720
    Abstract: The present invention relates, in part, to methods of treatment, prevention, and inhibition of viral disorders. In one aspect, the present invention relates to inhibition of the M2 proton channel of influenza viruses (e.g. influenza A virus) and other similar viroporins (e.g., VP24 of Ebola and Marburg viruses; and NS3 protein of Bluetongue). The present invention further relates, inter alia, to compounds which have been shown to possess antiviral activity, in particular, inhibiting the M2 proton channel of influenza viruses.
    Type: Grant
    Filed: September 13, 2010
    Date of Patent: May 14, 2013
    Assignee: Influmedix, Inc.
    Inventors: Jizhou Wang, Xiaodong Fan, Lidia Cristian
  • ANTIVIRAL COMPOUNDS AND THEIR METHODS OF USE
    Publication number: 20120295886
    Abstract: The present disclosure provides compounds having affinity for the M2 proton channel, useful for the treatment of viral infections such as influenza, which are of the Formula (I): wherein R1, R2, and Y are as defined herein. Methods of preparing the compounds, pharmaceutical compositions containing the compounds, and methods of using the compounds in the treatment of viral infections such as influenza are also provided.
    Type: Application
    Filed: May 18, 2012
    Publication date: November 22, 2012
    Applicant: INFLUMEDIX, INC.
    Inventors: Jizhou Wang, Xiaodong Fan, Lidia Cristian
  • Neuraminidase Inhibitors And Compositions And Methods Related Thereto
    Publication number: 20110092557
    Abstract: The present invention provides compounds comprising amino acid R groups, compositions comprising the same, and methods of inhibiting neuraminidase and/or treating influenza, Pseudomonas aeruginosa, or Bacteroides fragilis infection in a mammal.
    Type: Application
    Filed: June 24, 2009
    Publication date: April 21, 2011
    Applicant: INFLUMEDIX INC.
    Inventors: Xiaodong Fan, Lidia Cristian
  • METHODS OF USE OF ANTIVIRAL COMPOUNDS
    Publication number: 20110065762
    Abstract: The present invention relates, in part, to methods of treatment, prevention, and inhibition of viral disorders. In one aspect, the present invention relates to inhibition of the M2 proton channel of influenza viruses (e.g. influenza A virus) and other similar viroporins (e.g., VP24 of Ebola and Marburg viruses; and NS3 protein of Bluetongue). The present invention further relates, inter alia, to compounds which have been shown to possess antiviral activity, in particular, inhibiting the M2 proton channel of influenza viruses.
    Type: Application
    Filed: September 13, 2010
    Publication date: March 17, 2011
    Inventors: Jizhou Wang, Xiaodong Fan, Lidia Cristian
  • METHODS OF USE OF ANTIVIRAL COMPOUNDS
    Publication number: 20110065766
    Abstract: The present invention relates, in part, to methods of treatment, prevention, and inhibition of viral disorders. In one aspect, the present invention relates to inhibition of the M2 proton channel of influenza viruses (e.g. influenza A virus) and other similar viroporins (e.g., VP24 of Ebola and Marburg viruses; and NS3 protein of Bluetongue). The present invention further relates, inter alia, to compounds which have been shown to possess antiviral activity, in particular, inhibiting the M2 proton channel of influenza viruses.
    Type: Application
    Filed: September 13, 2010
    Publication date: March 17, 2011
    Inventors: Jizhou Wang, Xiaodong Fan, Lidia Cristian