Patents by Inventor Liduo Shen

Liduo Shen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • QUANTITATIVE DETERMINATION OF RISEDRONATE IN URINE BY SPE-LC-MS-MS
    Publication number: 20120193528
    Abstract: The present invention is directed to a SPE-LC-MS-MS method for quantitatively determining risedronate in a urine sample.
    Type: Application
    Filed: April 3, 2012
    Publication date: August 2, 2012
    Applicant: Sanofi-Aventis U.S. LLC
    Inventors: Liduo SHEN, Yongyi LUO
  • Quantitative determination of risedronate in urine by SPE-LC-MS-MS
    Patent number: 8168437
    Abstract: The disclosure provides a method for quantitatively determining risedronate in a urine sample by adding an internal standard to the urine sample, applying the urine sample to a polymeric water-wettable reverse-phased sorbent preconditioned with methanol, washing the sorbent with TEA in water and formic acid in methanol, eluting risedronate with a mixture of methanol and water containing EDTA under vacuum, evaporating the eluted solution and reconstituting with a mixture of methanol and NH4OH buffer and analyzing the sample with a LC-MS/MS system.
    Type: Grant
    Filed: September 4, 2009
    Date of Patent: May 1, 2012
    Assignee: Sanofi-Aventis U.S. LLC
    Inventors: Liduo Shen, Yongyi Luo
  • THE QUANTITATIVE DETERMINATION OF RISEDRONATE IN URINE BY SPE-LC-MS-MS
    Publication number: 20090320572
    Abstract: The present invention is directed to a SPE-LC-MS-MS method for quantitatively determining risedronate in a urine sample.
    Type: Application
    Filed: September 4, 2009
    Publication date: December 31, 2009
    Applicant: SANOFI-AVENTIS U.S. LLC
    Inventors: Liduo SHEN, Yongyi LUO