Abstract: The invention discloses 332 novel acetylation sites identified in various cancers, peptides (including AQUA peptides) comprising a acetylation site of the invention, antibodies specifically bind to a novel acetylation site of the invention, and diagnostic and therapeutic uses of the above.

Abstract: The invention discloses 443 novel phosphorylation sites identified in leukemia, peptides (including AQUA peptides) comprising a phosphorylation site of the invention, antibodies specifically bind to a novel phosphorylation site of the invention, and diagnostic and therapeutic uses of the above.

Abstract: Systems and methods for shape registration are described. In one aspect, training shape vectors are generated from images in an image database. The training shape vectors identify landmark points associated with one or more object types. A distribution of shape in the training shape vectors is represented as a prior of tangent shape in tangent shape space. The prior of tangent shape is then incorporated into a unified Bayesian framework for shape registration.

Abstract: A face model having outer and inner facial features is matched to that of first and second models. Each facial feature of the first and second models is represented by plurality of points that are adjusted for each matching outer and inner facial feature of the first and second models using 1) the corresponding epipolar constraint for the inner features of the first and second models. 2) Local grey-level structure of both outer and inner features of the first and second models. The matching and the adjusting are repeated, for each of the first and second models, until the points for each of the outer and inner facial features on the respective first and second models that are found to match that of the face model have a relative offset there between of not greater than a predetermined convergence tolerance. The inner facial features can include a pair of eyes, a nose and a mouth. The outer facial features can include a pair of eyebrows and a silhouette of the jaw, chin, and cheeks.

Abstract: Systems and methods for shape registration are described. In one aspect, training shape vectors are generated from images in an image database. The training shape vectors identify landmark points associated with one or more object types. A distribution of shape in the training shape vectors is represented as a prior of tangent shape in tangent shape space. The prior of tangent shape is then incorporated into a unified Bayesian framework for shape registration.

Abstract: A face model having outer and inner facial features is matched to that of first and second models. Each facial feature of the first and second models is represented by plurality of points that are adjusted for each matching outer and inner facial feature of the first and second models using 1) the corresponding epipolar constraint for the inner features of the first and second models. 2) Local grey-level structure of both outer and inner features of the first and second models. The matching and the adjusting are repeated, for each of the first and second models, until the points for each of the outer and inner facial features on the respective first and second models that are found to match that of the face model have a relative offset there between of not greater than a predetermined convergence tolerance. The inner facial features can include a pair of eyes, a nose and a mouth. The outer facial features can include a pair of eyebrows and a silhouette of the jaw, chin, and cheeks.