Patents by Inventor Lien H. Koztecki

Lien H. Koztecki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystalline forms of oxymorphone hydrochloride
    Patent number: 8563571
    Abstract: The present invention is directed to crystalline forms of oxymorphone hydrochloride.
    Type: Grant
    Filed: July 21, 2011
    Date of Patent: October 22, 2013
    Assignee: Noramco, Inc.
    Inventors: Karen S. Gushurst, Leonard J. Chyall, Lien H. Koztecki, Brenton Skylar Wolfe
  • POLYMORPHS OF SUCCINATE SALT OF 2-[6-(3-AMINO-PIPERIDIN-1-YL)-3-METHYL-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YLMETHY]-4-FLUOR-BENZONITRILE AND METHODS OF USE THEREFOR
    Publication number: 20120197018
    Abstract: Compositions comprising the succinate salt of 2-[6-(3-Amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethyl]-4-fluoro-benzonitrile (referred to herein as Compound I) which has the formula: wherein the Compound I is present in one or more polymorphic forms. Also provided are novel methods for the preparation of the polymorphs of Compound I, and kits and articles of manufacture of the compositions, and methods of using the compositions to treat various diseases.
    Type: Application
    Filed: February 15, 2012
    Publication date: August 2, 2012
    Inventors: Ron C. Kelly, Lien H. Koztecki
  • CRYSTALLINE FORMS OF OXYMORPHONE HYDROCHLORIDE
    Publication number: 20120022093
    Abstract: The present invention is directed to crystalline forms of oxymorphone hydrochloride.
    Type: Application
    Filed: July 21, 2011
    Publication date: January 26, 2012
    Inventors: Karen S. Gushurst, Leonard J. Chyall, Lien H. Koztecki, Brenton Skylar Wolfe
  • Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor
    Patent number: 8084605
    Abstract: Compositions comprising the succinate salt of 2-[6-(3-Amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethyl]-4-fluoro-benzonitrile (referred to herein as Compound I) which has the formula: wherein the Compound I is present in one or more polymorphic forms. Also provided are novel methods for the preparation of the polymorphs of Compound I, and kits and articles of manufacture of the compositions, and methods of using the compositions to treat various diseases.
    Type: Grant
    Filed: November 29, 2007
    Date of Patent: December 27, 2011
    Inventors: Ron C. Kelly, Lien H. Koztecki
  • POLYMORPHS OF NICOTINIC INTERMEDIATES
    Publication number: 20100062046
    Abstract: Crystalline forms of compounds (II), (III) and (IV) and processes to produce them are provided.
    Type: Application
    Filed: November 9, 2007
    Publication date: March 11, 2010
    Inventors: Douglas J.M. Allen, Travis L. Houston, Lien H. Koztecki, Melissa J. Casteel, David Burns Damon
  • POLYMORPHS OF SUCCINATE SALT OF 2-[6-(3-AMINO-PIPERIDIN-1-YL)-3-METHYL-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YLMETHY]-4-FLUOR-BENZONITRILE AND METHODS OF USE THEREFOR
    Publication number: 20080280931
    Abstract: Compositions comprising the succinate salt of 2-[6-(3-Amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethyl]-4-fluoro-benzonitrile (referred to herein as Compound I) which has the formula: wherein the Compound I is present in one or more polymorphic forms. Also provided are novel methods for the preparation of the polymorphs of Compound I, and kits and articles of manufacture of the compositions, and methods of using the compositions to treat various diseases.
    Type: Application
    Filed: November 29, 2007
    Publication date: November 13, 2008
    Inventors: Ron C. Kelly, Lien H. Koztecki
  • POLYMORPHS OF SUCCINATE SALT OF 2-[6-(3-AMINO-PIPERIDIN-1-YL)-3-METHYL-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YLMETHY]-4-FLUOR-BENZONITRILE AND METHODS OF USE THEREFOR
    Publication number: 20080227798
    Abstract: Compositions comprising the succinate salt of 2-[6-(3-Amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethyl]-4-fluoro-benzonitrile (referred to herein as Compound I) which has the formula: wherein the Compound I is present in one or more polymorphic forms. Also provided are novel methods for the preparation of the polymorphs of Compound I, and kits and articles of manufacture of the compositions, and methods of using the compositions to treat various diseases.
    Type: Application
    Filed: November 29, 2007
    Publication date: September 18, 2008
    Inventors: Ron C. KELLY, Lien H. Koztecki