Patents by Inventor Lien-Lung Sheu
Lien-Lung Sheu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11324912Abstract: The principles and embodiments of the present invention relate to methods and systems for safely providing NO to a recipient for inhalation therapy. There are many potential safety issues that may arise from using a reactor cartridge that converts NO2 to NO, including exhaustion of consumable reactants of the cartridge reactor. Accordingly, various embodiments of the present invention provide systems and methods of determining the remaining useful life of a NO2-to-NO reactor cartridge and/or a break-through of NO2, and providing an indication of the remaining useful life and/or break-through.Type: GrantFiled: November 26, 2019Date of Patent: May 10, 2022Assignee: Mallinckrodt Pharmaceuticals Ireland LimitedInventors: Jaron Acker, Muhammad Asif, Craig Flanagan, Douglas Alan Greene, Sarah Jayne Ridley, Frank Kenneth Schweighardt, Lien-Lung Sheu
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Publication number: 20200094010Abstract: The principles and embodiments of the present invention relate to methods and systems for safely providing NO to a recipient for inhalation therapy. There are many potential safety issues that may arise from using a reactor cartridge that converts NO2 to NO, including exhaustion of consumable reactants of the cartridge reactor. Accordingly, various embodiments of the present invention provide systems and methods of determining the remaining useful life of a NO2-to-NO reactor cartridge and/or a break-through of NO2, and providing an indication of the remaining useful life and/or break-through.Type: ApplicationFiled: November 26, 2019Publication date: March 26, 2020Inventors: Jaron Acker, Muhammad Asif, Craig Flanagan, Douglas Alan Greene, Sarah Jayne Ridley, Frank Kenneth Schweighardt, Lien-Lung Sheu
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Patent number: 10525226Abstract: The principles and embodiments of the present invention relate to methods and systems for safely providing NO to a recipient for inhalation therapy. There are many potential safety issues that may arise from using a reactor cartridge that converts NO2 to NO, including exhaustion of consumable reactants of the cartridge reactor. Accordingly, various embodiments of the present invention provide systems and methods of determining the remaining useful life of a NO2-to-NO reactor cartridge and/or a break-through of NO2, and providing an indication of the remaining useful life and/or break-through.Type: GrantFiled: May 14, 2015Date of Patent: January 7, 2020Assignee: Mallinckrodt Hospital Products IP LimitedInventors: Jaron Acker, Muhammad Asif, Craig Flanagan, Douglas Alan Greene, Sarah Jayne Ridley, Frank Kenneth Schweighardt, Lien-Lung Sheu
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Patent number: 10414578Abstract: An actuator for operatively engaging and dispensing a fluent medicament from a package in the form of a spray. The actuator includes a housing to receive and hold the package and further includes a force amplification mechanism that is connected to, and movable with respect to, the housing. The housing further includes a force transfer mechanism operatively engaged with a portion of the package. The force amplification mechanism is coupled with force transfer mechanism for accumulating a force sufficient to dispense the medicament from the package in the form of a spray.Type: GrantFiled: May 24, 2018Date of Patent: September 17, 2019Assignee: INSYS DEVELOPMENT COMPANY, INC.Inventors: Ethan R. Naylor, Lien-Lung Sheu
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Publication number: 20180339842Abstract: An actuator for operatively engaging and dispensing a fluent medicament from a package in the form of a spray. The actuator includes a housing to receive and hold the package and further includes a force amplification mechanism that is connected to, and movable with respect to, the housing. The housing further includes a force transfer mechanism operatively engaged with a portion of the package. The force amplification mechanism is coupled with force transfer mechanism for accumulating a force sufficient to dispense the medicament from the package in the form of a spray.Type: ApplicationFiled: May 24, 2018Publication date: November 29, 2018Inventors: Ethan R. Naylor, Lien-Lung Sheu
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Publication number: 20150328429Abstract: The principles and embodiments of the present invention relate to methods and systems for safely providing NO to a recipient for inhalation therapy. There are many potential safety issues that may arise from using a reactor cartridge that converts NO2 to NO, including exhaustion of consumable reactants of the cartridge reactor. Accordingly, various embodiments of the present invention provide systems and methods of determining the remaining useful life of a NO2-to-NO reactor cartridge and/or a break-through of NO2, and providing an indication of the remaining useful life and/or break-through.Type: ApplicationFiled: May 14, 2015Publication date: November 19, 2015Inventors: Jaron Acker, Muhammad Asif, Craig Flanagan, Douglas Alan Greene, Sarah Jayne Ridley, Frank Kenneth Schweighardt, Lien-Lung Sheu
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Patent number: 8267081Abstract: A therapy utilizing inhaled anesthetic agents (such as desflurane, sevoflurane, isoflurane, or xenon) for the sedation of patients outside of the immediate perioperative space such as in the medical intensive care unit (MICU) and the surgical intensive care unit (SICU). The therapy includes controlled delivery of volatile anesthetic agents to patients undergoing ventilatory support on an ICU ventilator over extended periods of time. A system which provides for the delivery of anesthetic agents includes an anesthetic agent vaporizer element, an anesthetic agent reflector, and a plug-in cassette which contains both a cartridge housing liquid phase volatile anesthetic agent and an anesthetic vapor scrubbing medium.Type: GrantFiled: February 20, 2009Date of Patent: September 18, 2012Assignees: Baxter International Inc., Baxter Healthcare S.A.Inventors: Craig T. Flanagan, William S. Hurst, Lien-Lung Sheu, Thomas A. Block, Haiming Wu
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Publication number: 20100212668Abstract: A therapy utilizing inhaled anesthetic agents (such as desflurane, sevoflurane, isoflurane, or xenon) for the sedation of patients outside of the immediate perioperative space such as in the medical intensive care unit (MICU) and the surgical intensive care unit (SICU). The therapy includes controlled delivery of volatile anesthetic agents to patients undergoing ventilatory support on an ICU ventilator over extended periods of time. A system which provides for the delivery of anesthetic agents includes an anesthetic agent vaporizer element, an anesthetic agent reflector, and a plug-in cassette which contains both a cartridge housing liquid phase volatile anesthetic agent and an anesthetic vapor scrubbing medium.Type: ApplicationFiled: February 20, 2009Publication date: August 26, 2010Applicants: BAXTER INTERNATIONAL INC., BAXTER HEAL THCARE S.A.Inventors: CRAIG T. FLANAGAN, WILLIAM S. HURST, LIEN-LUNG SHEU, THOMAS A. BLOCK, HAIMING WU
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Patent number: 5692495Abstract: A therapeutic oxygen-nitric oxide gas mixture is produced by passing air, oxygen-enriched air or air containing a small amount of ammonia over a noble metal catalyst at an elevated temperature. The product gas containing nitric oxide and a small amount of nitrogen dioxide is passed through a bed of an adsorbent which preferentially adsorbs nitrogen dioxide to produce nitric oxide-containing air suitable for administering to humans as an inhalant.Type: GrantFiled: April 2, 1996Date of Patent: December 2, 1997Assignee: The BOC Group, Inc.Inventor: Lien-Lung Sheu
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Patent number: 5670127Abstract: Nitric oxide is produced by reacting aqueous nitric acid with gaseous sulfur dioxide in a gas-liquid contact reactor. The reaction is conducted in the presence of a stoichiometric excess of nitric acid to minimize the production of byproduct nitrous oxide and nitrogen. The nitric oxide product gas is chilled sufficiently to freeze most of the water and byproduct nitrogen dioxide contained in the nitric oxide product gas. Residual nitrogen dioxide can be removed by adsorptive separation using an adsorbent which preferentially adsorbs nitrogen dioxide.Type: GrantFiled: September 26, 1995Date of Patent: September 23, 1997Assignee: The BOC Group, Inc.Inventor: Lien-Lung Sheu
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Patent number: 5670125Abstract: A gas mixture comprised of nitric oxide and, optionally an inert gas, and containing small amounts of nitrogen dioxide, and perhaps moisture and sulfur dioxide, is purified by passing the gas stream through a bed of zeolite having a silica to alumina ratio not greater than about 200. The concentration of nitrogen dioxide, sulfur dioxide and moisture in the gas stream are reduced to about 1 ppm or less as the gas mixture passes through the bed of zeolite.Type: GrantFiled: September 25, 1995Date of Patent: September 23, 1997Assignee: The BOC Group, Inc.Inventors: Lien-Lung Sheu, Ramakrishnan Ramachandran, Theodore R. Galica
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Patent number: 5514204Abstract: A gas mixture comprised of nitric oxide and, optionally an inert gas, and containing small amounts of nitrogen dioxide, and perhaps moisture and sulfur dioxide, is purified by passing the gas stream through a bed of metal cation-free silica, alumina, or zeolite. The concentration of nitrogen dioxide, sulfur dioxide and moisture in the gas stream are significantly reduced as the gas mixture passes through the bed of adsorbent.Type: GrantFiled: July 7, 1994Date of Patent: May 7, 1996Assignee: The BOC Group, Inc.Inventors: Lien-Lung Sheu, Ramakrishnan Ramachandran, Theodore R. Galica
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Patent number: 5417950Abstract: A gas mixture comprised of nitric oxide and, optionally an inert gas, and containing small amounts of nitrogen dioxide, and perhaps moisture and sulfur dioxide, is purified by passing the gas stream through a bed of metal cation-free alumina-deficient zeolites of types Y or ZSM-5. The concentrations of nitrogen dioxide, sulfur dioxide and moisture in the gas stream are reduced to about 1 ppm or less as the gas mixture passes through the bed of zeolite.Type: GrantFiled: July 7, 1994Date of Patent: May 23, 1995Assignee: The BOC Group, Inc.Inventors: Lien-Lung Sheu, Martin Bulow
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Patent number: 5262547Abstract: Petrochemicals are produced by the vapor phase reaction of a hydrocarbon with substantially pure oxygen in the presence of a suitable catalyst. In the improved process, the principal product is removed, carbon monoxide, present in the reactor effluent as a byproduct, is oxidized to carbon dioxide and part of the gaseous effluent, comprised mainly of carbon dioxide and unreacted hydrocarbon, is recycled to the reactor. Removal of carbon monoxide from the recycle stream reduces the hazard of a fire or explosion in the reactor or associated equipment. The use of carbon dioxide as the principal diluent increases heat removal from the reactor, thereby increasing the production capacity of the reactor.Type: GrantFiled: October 15, 1991Date of Patent: November 16, 1993Assignee: The BOC Group, Inc.Inventors: Ramakrishnan Ramachandran, Arthur I. Shirley, Lien-Lung Sheu
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Patent number: 5126463Abstract: This invention provides a process for the production of an anhydride by the vapor phase reaction of a hydrocarbon with substantially pure oxygen in the presence of a suitable catalyst. In the improved process, the anhydride product is removed, carbon monoxide, present in the reactor effluent as a by-product, is oxidized to carbon dioxide and part of the gaseous effluent, comprised mainly of carbon dioxide and unreacted hydrocarbon, is recycled to the reactor. Removal of carbon monoxide from the recycle stream reduces the hazard of a fire or explosion in the reactor or associated equipment. The use of carbon dioxide as the principal diluent increases heat removal from the reactor, thereby increasing the production capacity of the reactor.Type: GrantFiled: October 31, 1990Date of Patent: June 30, 1992Assignee: The BOC Group, Inc.Inventors: Ramakrishnan Ramachandran, Arthur I. Shirley, Lien-Lung Sheu