Patents by Inventor Lien-Yu Hung

Lien-Yu Hung has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10274497
    Abstract: An aptamer specific to ovarian cancer and a detection method for ovarian cancer are provided. The aptamer includes a following nucleotide sequence: 5?-ncaaannncnnnnanncnnnnnnnnnnngaannnannngg-3?, wherein n is a nucleotide independently selected from “a,” “t,” “c,” and “g.
    Type: Grant
    Filed: February 6, 2017
    Date of Patent: April 30, 2019
    Assignee: National Tsing Hua University
    Inventors: Gwo-Bin Lee, Lien-Yu Hung, Chih-Hung Wang, Chien-Yu Fu, Wen-Bin Lee
  • Patent number: 10107817
    Abstract: The present disclosure relates to an oligopeptide which is highly specific to an ovarian cancer. The oligopeptide includes an amino acid sequence of SEQ ID NO: 1. The present disclosure also relates to a test kit including the oligopeptide for detecting ovarian cancer and an ovarian cancer detection method by using the oligopeptide.
    Type: Grant
    Filed: January 20, 2017
    Date of Patent: October 23, 2018
    Assignee: NATIONAL TSING HUA UNIVERSITY
    Inventors: Gwo-Bin Lee, Lien-Yu Hung, Chih-Hung Wang, Chien-Yu Fu, Wen-Bin Lee
  • Publication number: 20180136217
    Abstract: An aptamer specific to ovarian cancer and a detection method for ovarian cancer are provided. The aptamer includes a following nucleotide sequence: 5?-ncaaannncnnnnanncnnnimnnnnngaannnannngg-3?, wherein n is a nucleotide independently selected from “a,” “t,” “c,” and “g.
    Type: Application
    Filed: February 6, 2017
    Publication date: May 17, 2018
    Applicant: National Tsing Hua University
    Inventors: Gwo-Bin Lee, Lien-Yu Hung, Chih-Hung Wang, Chien-Yu Fu, Wen-Bin Lee
  • Publication number: 20180133713
    Abstract: A microfluidic in-vitro screening chip system including a first micromixer chamber, a plurality of first storage chambers, a second micromixer chamber and a plurality of second storage chambers. The first micromixer chamber includes a non-target disease tissue slide region. The plurality of first storage chambers are connected to the first micromixer chamber, wherein at least one first storage chamber is used for storing a library. The second micromixer chamber is connected to the first micromixer chamber, and the second micromixer chamber includes a target disease tissue slide region. The plurality of second storage chambers are connected to the second micromixer chamber.
    Type: Application
    Filed: February 14, 2017
    Publication date: May 17, 2018
    Applicant: National Tsing Hua University
    Inventors: Gwo-Bin Lee, Lien-Yu Hung, Chih-Hung Wang, Chien-Yu Fu, Wen-Bin Lee
  • Publication number: 20180113136
    Abstract: The present disclosure relates to an oligopeptide which is highly specific to an ovarian cancer. The oligopeptide includes an amino acid sequence of SEQ ID NO: 1. The present disclosure also relates to a test kit including the oligopeptide for detecting ovarian cancer and an ovarian cancer detection method by using the oligopeptide.
    Type: Application
    Filed: January 20, 2017
    Publication date: April 26, 2018
    Inventors: Gwo-Bin LEE, Lien-Yu HUNG, Chih-Hung WANG, Chien-Yu FU, Wen-Bin LEE
  • Patent number: 9783808
    Abstract: The present invention provides ovarian cancer-specific aptamers, which are selected in vitro using SELEX and a microfluidic chip system. The aptamers can also bind to different histologically-classified ovarian cancer cells with high affinity accordingly. Therefore, the aptamers of the present invention and the applications thereof can not only be used in detection of ovarian cancer cells but also be applied in recognition of different histologically-classified ovarian cancer cells.
    Type: Grant
    Filed: December 2, 2014
    Date of Patent: October 10, 2017
    Assignee: National Tsing Hua University
    Inventors: Gwo-Bin Lee, Lien-Yu Hung, Chih-Hung Wang
  • Publication number: 20170074882
    Abstract: The present invention provides an oligopeptide specific to colorectal cancer cells, which are selected from a group of peptide sequences consisting of Seq ID: NO. 1 to Seq ID: NO. 3.
    Type: Application
    Filed: November 3, 2016
    Publication date: March 16, 2017
    Inventors: Gwo-Bin LEE, Yu-Jui CHE, Chih-Hung WANG, Lien-Yu HUNG
  • Publication number: 20160153997
    Abstract: The present invention provides an oligopeptide specific to colorectal cancer cells, which are selected from a group of peptide sequences consisting of Seq ID: NO. 1 to Seq ID: NO. 3.
    Type: Application
    Filed: March 18, 2015
    Publication date: June 2, 2016
    Inventors: Gwo-Bin LEE, Yu-Jui CHE, Chih-Hung WANG, Lien-Yu HUNG
  • Publication number: 20160097101
    Abstract: The present invention provides an aptamer specific to colorectal cancer cells and comprises a nucleotide sequence selected from the group consisting of Seq ID: NO. 1 to Seq ID: NO. 14. The aptamer of the present invention specific to colorectal cancer cell may be applied in colorectal cancer detection and provide a detection method having non-invasive, fast and convenient properties.
    Type: Application
    Filed: January 13, 2015
    Publication date: April 7, 2016
    Inventors: Gwo-Bin LEE, Lien-Yu HUNG, Chih-Hung WANG
  • Publication number: 20160061840
    Abstract: The present invention provides ovarian cancer-specific aptamers, which are selected in vitro using SELEX and a microfluidic chip system. The aptamers can also bind to different histologically-classified ovarian cancer cells with high affinity accordingly. Therefore, the aptamers of the present invention and the applications thereof can not only be used in detection of ovarian cancer cells but also be applied in recognition of different histologically-classified ovarian cancer cells.
    Type: Application
    Filed: December 2, 2014
    Publication date: March 3, 2016
    Inventors: Gwo-Bin Lee, Lien-Yu Hung, Chih-Hung Wang