Patents by Inventor Lies Dekeyzer

Lies Dekeyzer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CHIMERIC PROTEINS AND METHODS TO SCREEN FOR COMPOUNDS AND LIGANDS BINDING TO GPCRS
    Publication number: 20220276244
    Abstract: The invention relates to chimeric GPCRs having extracellular loops from a first GPCR and intracellular loops from a second GPCR, and to screening methods for identifying compounds or ligands that bind to an active conformation of a GPCR in which such chimeric GPCRs are used.
    Type: Application
    Filed: April 28, 2020
    Publication date: September 1, 2022
    Inventors: Ann De Blieck, Pieter Claes, Cedric Ververken, Christel Menet, Lies Dekeyzer
  • Screening Methods and Assays for Use with Transmembrane Proteins, in Particular with GPCRs
    Publication number: 20220244254
    Abstract: The invention provides methods and arrangements for screening membrane proteins. The arrangement comprises a first fusion protein comprising a membrane protein present in a boundary layer such as a wall of a cell, liposome or vesicle fused to one member of a binding pair and a second fusion protein comprising an intracellular ligand of said membrane protein fused to another member of the binding pair, in which the binding pair is capable of generating a detectable signal.
    Type: Application
    Filed: April 28, 2020
    Publication date: August 4, 2022
    Inventors: Christel Menet, Lies Dekeyzer, Murielle Martini, Kamila Skieterska
  • IMPROVED PHARMACOKINETIC ASSAYS FOR IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS
    Publication number: 20190195866
    Abstract: The present invention generally relates to improved pharmacokinetic assays for measuring levels of immunoglobulin single variable domains (also referred to herein as “ISVs” or “ISVDs”) and of proteins and polypeptides that comprise at least one ISV (as further described herein) in biological samples.
    Type: Application
    Filed: June 21, 2017
    Publication date: June 27, 2019
    Applicant: Ablynx N.V.
    Inventors: Veerle Snoeck, Lieselot Bontinck, Sofie Poelmans, Kjell Mortier, Marie-Ange Buyse, Lies Dekeyzer, Judith Baumeister