Patents by Inventor Lieve Michiels

Lieve Michiels has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing and crosslinking a cable comprising a polymer composition and a crosslinked cable
    Patent number: 8399049
    Abstract: The application relates to a process for preparing a crosslinked cable, including:—applying one or more layers including a polymer composition on a conductor, wherein at least one layer includes one or more free radical generating agents,—crosslinking by radical reaction said at least one layer comprising said free radical generating agent(s),—cooling the obtained crosslinked cable in pressurized conditions.
    Type: Grant
    Filed: July 10, 2008
    Date of Patent: March 19, 2013
    Assignee: Borealis Technology Oy
    Inventors: Paul Laurenson, Detlef Wald, Erik Perzon, John Jamieson, Siegfried Wegener, Rudi Peters, Annika Smedberg, Lieve Michiels, Jan-Ove Bosstrom
  • Process for Preparing and Crosslinking a Cable Comprising a Polymer Composition and a Crosslinked Cable
    Publication number: 20100193217
    Abstract: The application relates to a process for preparing a crosslinked cable, including:—applying one or more layers including a polymer composition on a conductor, wherein at least one layer includes one or more free radical generating agents,—crosslinking by radical reaction said at least one layer comprising said free radical generating agent(s),—cooling the obtained crosslinked cable in pressurized conditions.
    Type: Application
    Filed: July 10, 2008
    Publication date: August 5, 2010
    Applicant: BOREALIS TECHNOLOGY OY
    Inventors: Paul Laurenson, Detlef Wald, Erik Perzon, John Jamieson, Siegfried Wegener, Rudi` Peters, Annika Smedberg, Lieve Michiels, Jan-Ove Bostrom
  • METHODS OF ASSESSING HIV INTEGRASE INHIBITOR THERAPY
    Publication number: 20070134766
    Abstract: The present invention relates to methods and products for the evaluation of HIV treatment. The methods are based on evaluating molecular events at the HIV integrase resulting in altered therapeutic efficacy of the investigated compounds. The methods rely on providing an integrase gene and evaluating either through genotyping or phenotyping said integrase gene. The present invention relates to the fields of diagnostics, drug screening, pharmacogenetics and drug development.
    Type: Application
    Filed: February 1, 2007
    Publication date: June 14, 2007
    Inventors: Johan Vingerhoets, Lieve Michiels, Inge Dierynck
  • Entry inhibitors of the hiv virus
    Publication number: 20070066623
    Abstract: The present invention relates to small molecules as entry inhibitors of the HIV virus, processes for their preparation as well as pharmaceutical compositions, their use as medicines, and diagnostic kits comprising them. The present invention also concerns combinations of the present entry inhibitors with other anti-retroviral agents. It further relates to their use in assays as reference compounds or as reagents. The compounds of the present invention are useful for preventing or treating infection by HIV and for treating AIDS.
    Type: Application
    Filed: September 10, 2004
    Publication date: March 22, 2007
    Inventors: Koenraad Van Acker, Piet Wigerinck, Lieve Michiels, Abdellah Tahri
  • Methods of assessing HIV integrase inhibitor therapy
    Publication number: 20060029934
    Abstract: The present invention relates to methods and products for the evaluation of HIV treatment. The methods are based on evaluating molecular events at the HIV integrase resulting in altered therapeutic efficacy of the investigated compounds. The methods rely on providing an integrase gene and evaluating either through genotyping or phenotyping said integrase gene. The present invention relates to the fields of diagnostics, drug screening, pharmacogenetics and drug development.
    Type: Application
    Filed: August 15, 2005
    Publication date: February 9, 2006
    Inventors: Johan Vingerhoets, Lieve Michiels, Inge Dierynck
  • Small molecule entry inhibitors
    Publication number: 20060025594
    Abstract: The present invention concerns a compound having the formula (I) a N-oxide form, a stereochemical isomer, racemic mixture, salt, prodrug, ester or metabolite thereof. It further relates to processes for their preparation as well as pharmaceutical compositions, their use as medicines, and diagnostic kits comprising them. The present invention also concerns combinations of the present entry inhibitors with anti-retroviral agents. It further relates to their use in assays as reference compounds or as reagents. The compounds of the present invention are useful for preventing or treating infection by HIV and for treating AIDS.
    Type: Application
    Filed: March 11, 2003
    Publication date: February 2, 2006
    Applicant: TIBOTEC Pharmaceuticals Ltd.
    Inventors: Marie-Pierre De Bethune, Sandra De Meyer, Kurt Hertogs, Rong Lu, Lieve Michiels, Abdellah Tahri, Dong Xie, Michael Eissenstat