Patents by Inventor Lieven De Veylder
Lieven De Veylder has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11939586Abstract: The present invention relates to the field of plant genetic engineering, particularly the modulation of gene expression in plant cells for improved regeneration competence. The invention discloses means and methods wherein the Ethylene Response Factor (ERF) and Phytochrome A Signal Transduction 1 (PAT1) transcription factor complex activity in plant cells grants increased regeneration.Type: GrantFiled: October 11, 2017Date of Patent: March 26, 2024Assignees: VIB VZW, Universiteit GentInventors: Lieven De Veylder, Jefri Heyman
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Patent number: 11193136Abstract: The present invention relates to specific inhibitors of the cellulose synthase subunits 1 and 3 activity in plants, useful as a herbicide. In addition, the invention relates to mutant plants which are tolerant to the identified inhibitors. Specific mutant alleles of CESA1 and CESA3 genes can be used to obtain resistance in a plant when the inhibitors are used as herbicide.Type: GrantFiled: August 1, 2017Date of Patent: December 7, 2021Assignees: VIB VZW, UniversiteitGentInventors: Lieven De Veylder, Rudy Vanderhaeghen, Zhubing Hu
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Publication number: 20190225976Abstract: The present invention relates to the field of plant genetic engineering, particularly the modulation of gene expression in plant cells for improved regeneration competence. The invention discloses means and methods wherein the Ethylene Response Factor (ERF) and Phytochrome A Signal Transduction 1 (PAT1) transcription factor complex activity in plant cells grants increased regeneration.Type: ApplicationFiled: October 11, 2017Publication date: July 25, 2019Inventors: Lieven De Veylder, Jefri Heyman
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Publication number: 20190177743Abstract: The present invention relates to specific inhibitors of the cellulose synthase subunits 1 and 3 activity in plants, useful as a herbicide. In addition, the invention relates to mutant plants which are tolerant to the identified inhibitors. Specific mutant alleles of CESA1 and CESA3 genes can be used to obtain resistance in a plant when the inhibitors are used as herbicide.Type: ApplicationFiled: August 1, 2017Publication date: June 13, 2019Inventors: Lieven De Veylder, Rudy Vanderhaeghen, Zhubing Hu
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Publication number: 20160272992Abstract: Described is the use of SMR5, possibly in combination with SMR4 and/or SMR7, to modulate ROS and oxidative stress response in plants. More specifically, it relates to an SMR5 knock out or knock down to improve the oxidative stress tolerance in plants.Type: ApplicationFiled: November 17, 2014Publication date: September 22, 2016Inventors: Lieven De Veylder, Toon Cools
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Patent number: 8853492Abstract: The present invention relates generally to the field of molecular biology and concerns a method for improving plant growth characteristics relative to corresponding wild type plants. More specifically, the present invention concerns a method for improving plant growth characteristics comprising modulating expression in a plant of a nucleic acid encoding a class I homeodomain leucine zipper (HDZip) hox5 polypeptide or a homologue thereof; or comprising modulating expression in a plant of a nucleic acid encoding a nitrate transporter protein (NRT) or a homologue thereof; or comprising modulating expression in a plant of a nucleic acid encoding a polypeptide denoted Yield Enhancing Protein 16 (YEP16); or comprising modulating expression in a plant of a Group I glycogen synthase kinase (Group I shaggy-like kinase) or a homologue thereof.Type: GrantFiled: April 30, 2007Date of Patent: October 7, 2014Assignee: CropDesign N.V.Inventors: Ana Isabel Sanz Molinero, Christophe Reuzeau, Yves Hatzfeld, Veronique Boudolf, Lieven de Veylder, Dirk Inze, Vladimir Mironov
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Publication number: 20120216320Abstract: The invention provides isolated nucleic acids molecules, designated CCP nucleic acid molecules, which encode novel cell cycle associated polypeptides. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing CCP nucleic acid molecules, host cells into which the expression vectors have been introduced, and transgenic plants in which a CCP gene has been introduced or disrupted. The invention still further provides isolated CCP proteins, fusion proteins, antigenic peptides and anti-CCP antibodies. Agricultural, diagnostic, screening, and therapeutic methods utilizing compositions of the invention are also provided.Type: ApplicationFiled: May 7, 2012Publication date: August 23, 2012Applicant: CropDesign N.V.Inventors: Dirk Inze, Veronique Boudolf, Lieven de Veylder, Juan Antonio Torres Acosta, Zoltan Magyar
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Patent number: 8193414Abstract: The present invention relates to the field of molecular biology. The invention provides a method for modulating growth of a plant comprising introducing into a plant a CCP (cell cycle protein) modulator. Further provided are nucleic acid molecules and the polypeptides encoded thereof useful as modulating agents for performing such methods.Type: GrantFiled: May 14, 2001Date of Patent: June 5, 2012Assignee: CropDesign N.V.Inventors: Dirk Inze, Veronique Boudolf, Lieven De Veylder, Juan Antonio Torres Acosta, Zoltan Magyar
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Publication number: 20110229491Abstract: The present invention relates to a protein that is interacting with the minichromosome maintenance complex in eukaryotes. More specifically, the invention relates to the use of a protein, interacting with the minichromosome complex, and the gene encoding this protein in diagnosis, prognosis and treatment of cancer.Type: ApplicationFiled: May 29, 2009Publication date: September 22, 2011Inventors: Lieven De Veylder, Geert Berx, Naoki Takahashi, Mauricio Quimbaya, Eric Raspe
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Publication number: 20110162107Abstract: The present invention concerns a method for altering characteristics of a plant. The invention describes the identification of a gene that is downregulated in transgenic plants overexpressing E2Fa/DPa and the use of such sequences to alter plant characteristics. A preferred way for altering characteristics of a plant comprises modifying expression of one or more nucleic acid sequences and or modifying level and/or activity of one or more proteins, which nucleic acids and/or proteins encoded thereby are essentially similar to SEQ ID NO 1835. The gene identified in the present invention have an E2Fa target consensus sequence in their 5? upstream region. The identified gene is postulated to play a role as transcription factors.Type: ApplicationFiled: November 10, 2010Publication date: June 30, 2011Applicant: CROPDESIGN N.V.Inventors: Dirk INZE, Lieven De Veylder, Kobe Vlieghe
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Patent number: 7847156Abstract: The present invention concerns a method for altering characteristics of a plant. The invention describes the identification of a gene that is downregulated in transgenic plants overexpressing E2Fa/DPa and the use of such sequences to alter plant characteristics. A preferred way for altering characteristics of a plant comprises modifying expression of one or more nucleic acid sequences and or modifying level and/or activity of one or more proteins, which nucleic acids and/or proteins encoded thereby are essentially similar to SEQ ID NO 1835. The gene identified in the present invention have an E2Fa target consensus sequence in their 5? upstream region. The identified gene is postulated to play a role as transcription factors.Type: GrantFiled: October 20, 2003Date of Patent: December 7, 2010Assignee: Cropdesign N.V.Inventors: Dirk Inze, Lieven De Veylder, Kobe Vlieghe
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Method and means for modulating plant cell cycle proteins and their use in plant cell growth control
Patent number: 7825295Abstract: The present invention provides a method for modulating endoreduplication in a plant, plant part, or plant cell. The method comprises the steps of introduction and expression of a nucleotide sequence encoding the CDC2bAt cyclin dependent kinase gene disclosed in database accession number X57840 or said CDC2bAt cyclin dependent kinase gene having the Asp residue at position 161 replaced with an Asn residue, under the control of a promoter which functions in a plant.Type: GrantFiled: January 26, 2007Date of Patent: November 2, 2010Assignee: CropDesign N.V.Inventors: Dirk Inze, Gerda Segers, Lieven De Veylder, Vladimir Mironov -
Patent number: 7592507Abstract: The present invention relates to a method for modifying plant growth and development processes by affecting cell cycle regulation comprising modulating expression of members of the plant E2F transcription factor family. More specific the invention relates to methods for stimulating cell division in a plant. The invention further relates to transgenic plants produced by the methods of the invention having altered plant growth and development characteristics compared to their isogenic counterparts. Preferably, the plant characteristics modified by the present invention include enlarged cotyledons, enhanced growth rate, stress resistance and seedling survival, more cells, more tillers, more panicles.Type: GrantFiled: September 12, 2002Date of Patent: September 22, 2009Assignee: CrooDesign, N.V.Inventors: Tom Beeckman, Lieven De Veylder, Dirk Inze, Vladimir Mironov, Willem Broekaert, Willy Dillen, Valerie Frankard
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Publication number: 20090222952Abstract: The present invention concerns a method for increasing plant yield and/or increased stress resistance by decreasing the level of activity of a DEL1 polypeptide. One such method comprises introducing into a plant a nucleic acid comprising a variant DEL1 nucleic acid. Another method comprises downregulating expression of a DEL1 gene. The invention also relates to transgenic plants having introduced therein a variant DEL1 nucleic acid thereof, which plants have increased yield and/or increased stress resistance relative to control plants. The present invention also concerns a novel DEL1 protein and its encoding sequence, and constructs useful in the methods of the invention.Type: ApplicationFiled: November 8, 2006Publication date: September 3, 2009Applicants: CropDesign N.V., VIB vzw, Universiteit GentInventors: Jan de Meutter, Vladimir Mironov, Christophe Reuzeau, Dirk Inze, Kobe Vlieghe, Lieven de Veylder
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Publication number: 20080307546Abstract: Provided are DNA sequences encoding cyclin-dependent kinase inhibitor(s) as well as to methods for obtaining the same. Furthermore, vectors comprising said DNA sequences are described, wherein the DNA sequences are operatively linked to regulatory elements allowing expression in prokaryotic and/or eukaryotic host cells. In addition, proteins encoded by said DNA sequences, antibodies to said proteins and methods for their production are provided. Furthermore, regulatory sequences which naturally regulate the expression of the above described DNA sequences are described. Also described is a method for controlling or altering growth characteristics of a plant and/or a plant cell comprising introduction and/or expression of one or more cyclin-dependent kinase inhibitor(s) functional in a plant or parts thereof and/or one or more DNA sequences encoding such proteins.Type: ApplicationFiled: March 26, 2007Publication date: December 11, 2008Inventors: Lieven De Veylder, Tom Beeckman, Dirk Inze, Wim Van Camp, Luc Krols
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Publication number: 20080207449Abstract: The invention provides isolated nucleic acids molecules, designated CCP nucleic acid molecules, which encode novel cell cycle associated polypeptides. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing CCP, nucleic acid molecules, host cells into which the expression vectors have been introduced, and transgenic plants in which a CCP gene has been introduced or disrupted. The invention still further provides isolated CCP proteins, fusion proteins, antigenic peptides and anti-CCP antibodies. Agricultural, diagnostic, screening, and therapeutic methods utilizing compositions or the invention are also provided.Type: ApplicationFiled: May 14, 2001Publication date: August 28, 2008Applicant: CROPDESIGN N.V.Inventors: Dirk Inze, Veronique Boudolf, Lieven De Veylder, Juan Antonio Torres Acosta, Zoltan Magyar
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Publication number: 20080127365Abstract: The present invention relates generally to the field of molecular biology and concerns a method for improving plant growth characteristics relative to corresponding wild type plants. More specifically, the present invention concerns a method for improving plant growth characteristics comprising modulating expression in a plant of a nucleic acid encoding a class I homeodomain leucine zipper (HDZip) hox5 polypeptide or a homologue thereof; or comprising modulating expression in a plant of a nucleic acid encoding a nitrate transporter protein (NRT) or a homologue thereof; or comprising modulating expression in a plant of a nucleic acid encoding a polypeptide denoted Yield Enhancing Protein 16 (YEP16); or comprising modulating expression in a plant of a Group I glycogen synthase kinase (Group I shaggy-like kinase) or a homologue thereof.Type: ApplicationFiled: April 30, 2007Publication date: May 29, 2008Applicant: CropDesign N.V.Inventors: Ana Isabel Sanz Molinero, Christophe Reuzeau, Yves Hatzfeld, Veronique Boudolf, Lieven de Veylder, Dirk Inze, Vladimir Mironov
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Patent number: 7265267Abstract: Provided are DNA sequences encoding cyclin-dependent kinase inhibitor(s) as well as to methods for obtaining the same. Furthermore, vectors comprising said DNA sequences are described, wherein the DNA sequences are operatively linked to regulatory elements allowing expression in prokaryotic and/or eukaryotic host cells. In addition, proteins encoded by said DNA sequences, antibodies to said proteins and methods for their production are provided. Furthermore, regulatory sequences which naturally regulate the expression of the above described DNA sequences are described. Also described is a method for controlling or altering growth characteristics of a plant and/or a plant cell comprising introduction and/or expression of one or more cyclin-dependent kinase inhibitor(s) functional in a plant or parts thereof and/or one or more DNA sequences encoding such proteins.Type: GrantFiled: May 18, 2000Date of Patent: September 4, 2007Assignee: CropDesign N.V.Inventors: Lieven De Veylder, Tom Beeckman, Dirk Inze, Wim Van Camp, Luc Krols
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Publication number: 20050059154Abstract: The present invention relates to a method for modifying plant growth and development processes by affecting cell cycle regulation comprising modulating expression of members of the plant E2F transcription factor family. More specific the invention relates to methods for stimulating cell division in a plant. The invention further relates to transgenic plants produced by the methods of the invention having altered plant growth and development characteristics compared to their isogenic counterparts. Preferably, the plant characteristics modified by the present invention include enlarged cotyledons, enhanced growth rate, stress resistance and seedling survival, more cells, more tillers, more panicles.Type: ApplicationFiled: September 12, 2002Publication date: March 17, 2005Inventors: Tom Beeckman, Lieven De Veylder, Dirk Inze, Vladimir Mironov, Willem Broekaert, Willy Dillen, Valerie Frankard
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Publication number: 20040073969Abstract: Provided are DNA sequences encoding cyclin-dependent kinase inhibitor(s) as well as to methods for obtaining the same. Furthermore, vectors comprising said DNA sequences are described, wherein the DNA sequences are operatively linked to regulatory elements allowing expression in prokaryotic and/or eukaryotic host cells. In addition, proteins encoded by said DNA sequences, antibodies to said proteins and methods for their production are provided. Furthermore, regulatory sequences which naturally regulate the expression of the above described DNA sequences are described. Also described is a method for controlling or altering growth characteristics of a plant and/or a plant cell comprising introduction and/or expression of one or more cyclin-dependent kinase inhibitor(s) functional in a plant or parts thereof and/or one or more DNA sequences encoding such proteins.Type: ApplicationFiled: October 17, 2003Publication date: April 15, 2004Inventors: Dirk Inze, Lieven De Veylder, Janice De Almeida, Isabelle Landrieu