Patents by Inventor Lieven Elvire Colette Baert

Lieven Elvire Colette Baert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20080287488
    Abstract: A method for improving the pharmacokinetics of drugs, which are metabolized by cytochrome P450 monooxygenase is disclosed. More specifically it relates to a method for improving the pharmacokinetics of retroviral protease inhibitors and in particular for improving the pharmacokinetics of human immunodeficiency virus (HIV) protease inhibitors. A pharmaceutical composition and its use in the manufacture of a medicament for the inhibition or treatment of an HIV infection or AIDS in a human being are also part of the invention.
    Type: Application
    Filed: April 14, 2006
    Publication date: November 20, 2008
    Applicant: Tibotec Pharmaceuticals Ltd.
    Inventors: Gerben Albert Eleutherius Van 'T Klooster, Piet Tom Bert Paul Wigerinck, Sandra De Meyer, Lieven Elvire Colette Baert, Herman Augustinus De Kock
  • Publication number: 20080194601
    Abstract: This invention relates to the use of a parenteral formulation comprising the NNRTI TMC278 for the long term prevention of HIV infection in a subject at risk of being infected by HIV, which comprises the intermittent administration of the said formulation at long time intervals.
    Type: Application
    Filed: April 4, 2006
    Publication date: August 14, 2008
    Inventors: Lieven Elvire Colette Baert, Paulus Joannes Lewi, Jan Heeres
  • Patent number: 7081255
    Abstract: The present invention is concerned with novel pharmaceutical compositions of itraconazole which can be administered to a mammal suffering from a fungal infection, whereby a single such dosage form can be administered once daily, and in addition at any time of the day independently of the food taken in by said mammal. These novel compositions comprise particles obtainable by melt-extruding a mixture comprising itraconazole and an appropriate water-soluble polymer and subsequently milling said melt-extruded mixture.
    Type: Grant
    Filed: August 14, 2002
    Date of Patent: July 25, 2006
    Assignee: Janssen Pharmaceutica, N.V.
    Inventors: Lieven Elvire Colette Baert, Geert Verreck, Dany Thoné
  • Publication number: 20030082239
    Abstract: The present invention is concerned with novel pharmaceutical compositions of itraconazole which can be administered to a mammal suffering from a fungal infection, whereby a single such dosage form can be administered once daily, and in addition at any time of the day independently of the food taken in by said mammal. These novel compositions comprise particles obtainable by melt-extruding a mixture comprising itraconazole and an appropriate water-soluble polymer and subsequently milling said melt-extruded mixture.
    Type: Application
    Filed: August 14, 2002
    Publication date: May 1, 2003
    Applicant: Janssen Pharmaceutical, N.V.
    Inventors: Lieven Elvire Colette Baert, Geert Verreck, Dany Thone
  • Patent number: 6509038
    Abstract: The present invention is concerned with novel pharmaceutical compositions of itraconazole which can be administered to a mammal suffering from a fungal infection, whereby a single such dosage form can be administered once daily, and in addition at any time of the day independently of the food taken in by said mammal. These novel compositions comprise particles obtainable by melt-extruding a mixture comprising itraconazole and an appropriate water-soluble polymer and subsequently milling said melt-extruded mixture.
    Type: Grant
    Filed: November 19, 1998
    Date of Patent: January 21, 2003
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Lieven Elvire Colette Baert, Geert Verreck, Dany Thoné
  • Patent number: 6365188
    Abstract: Process for preparing a solid mixture comprising one or more cyclodextrins and an insoluble active ingredient characterized in that said process comprises a melt-extrusion step, wherein the active ingredient is embedded into the cyclodextrin carrier.
    Type: Grant
    Filed: May 20, 1998
    Date of Patent: April 2, 2002
    Assignee: Janssen Pharmaceutica, N.V.
    Inventors: Lieven Elvire Colette Baert, Jozef Peeters, Geert Verreck
  • Publication number: 20010007678
    Abstract: The present invention is concerned with novel pharmaceutical compositions of itraconazole which can be administered to a mammal suffering from a fungal infection, whereby a single such dosage form can be administered once daily, and in addition at any time of the day independently of the food taken in by said mammal. These novel compositions comprise particles obtainable by melt-extruding a mixture comprising itraconazole and an appropriate water-soluble polymer and subsequently milling said melt-extruded mixture.
    Type: Application
    Filed: November 19, 1998
    Publication date: July 12, 2001
    Inventors: LIEVEN ELVIRE COLETTE BAERT, GEERT VERRECK, DANY THONE