Patents by Inventor Lieven Meerpoel

Lieven Meerpoel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biphenylcarboxamides useful as lipid lowering agents
    Patent number: 7405307
    Abstract: Biphenylcarboxamide compounds of formula (I) methods for preparing such compounds, pharmaceutical compositions comprising said compounds as well as the use of said compounds as a medicine for the treatment of hyperlipidemia, obesity and type II diabetes.
    Type: Grant
    Filed: September 13, 2007
    Date of Patent: July 29, 2008
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Lieven Meerpoel, Leo Jacobs Jozef Backx
  • POLYARYLCARBOXAMIDES USEFUL AS LIPID LOWERING AGENTS
    Publication number: 20080125412
    Abstract: Polyarylcarboxamide compounds of formula (I) are useful as lipid lowering agents.
    Type: Application
    Filed: October 30, 2007
    Publication date: May 29, 2008
    Inventors: Lieven Meerpoel, Peter Walter Maria Roevens, Leo Jacobus Jozef Backx, Louis Jozef Elisabeth Van der Veken, Marcel Viellevoye
  • Sulfonyl-Derivatives as Novel Inhibitors or Histone Deacetylase
    Publication number: 20080108601
    Abstract: This invention comprises the novel compounds of formula (I) wherein n, m, t, R1, R2, R3, R4, L, Q, X, Y, Z and have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
    Type: Application
    Filed: October 29, 2007
    Publication date: May 8, 2008
    Inventors: Kristof Van Emelen, Janine Arts, Leo-Jacobus Backx, Hans De Winter, Sven Van Brandt, Marc Verdonck, Lieven Meerpoel, Isabelle Pilatte, Virginie Poncelet, Alexey Dyatkin, Jimmy Van heusden
  • Lipid Lowering Biphenylcarboxamides
    Publication number: 20080081813
    Abstract: Biphenylcarboxamide compounds of formula (I) methods for preparing such compounds, pharmaceutical compositions comprising said compounds as well as the use of said compounds as a medicine for the treatment of hyperlipidemia, obesity and type II diabetes.
    Type: Application
    Filed: March 27, 2002
    Publication date: April 3, 2008
    Inventors: Lieven Meerpoel, Marcel Viellevoye
  • BIPHENYLCARBOXAMIDES USEFUL AS LIPID LOWERING AGENTS
    Publication number: 20080009522
    Abstract: Biphenylcarboxamide compounds of formula (I) methods for preparing such compounds, pharmaceutical compositions comprising said compounds as well as the use of said compounds as a medicine for the treatment of hyperlipidemia, obesity and type II diabetes.
    Type: Application
    Filed: September 13, 2007
    Publication date: January 10, 2008
    Inventors: Lieven Meerpoel, Leo Jacobus Backx
  • Biphenylcarboxamides useful as lipid lowering agents
    Patent number: 7304167
    Abstract: Biphenylcarboxamide compounds of formula (I) methods for preparing such compounds, pharmaceutical compositions comprising said compounds as well as the use of said compounds as a medicine for the treatment of hyperlipidemia, obesity and type II diabetes.
    Type: Grant
    Filed: January 24, 2006
    Date of Patent: December 4, 2007
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Lieven Meerpoel, Leo Jacobs Jozef Backx
  • ANTIFUNGAL 4-SUBSTITUTED 5,6-DIHYDRO-4H-PYRROLO [1,2-a][1,4]BENZODIAZEPINES
    Publication number: 20070232593
    Abstract: The present invention concerns compounds for use as a medicine having the formula the N-oxide forms, the salts, the quaternary amines and stereochemically isomeric forms thereof, wherein R1 represents hydrogen, C1-6alkyl, C1-4alkylthio, C1-4alkyloxy, or halo; R2 represents hydrogen or C1-6alkyl; R3 represents phenyl substituted with halo, cyano, C1-4alkyloxy, C1-4alkylthio, C1-6alkyl, haloC1-6alkyl; 2-thienyl; or 3-thienyl, R4 represents hydrogen; or R2 and R4 form an extra bond, which are active against dermatophytes, and their preparation; it further relates to compositions comprising them, as well as their use as a medicine.
    Type: Application
    Filed: March 1, 2007
    Publication date: October 4, 2007
    Inventors: Terence Gilkerson, Roger Nash, Jozef Van Gestel, Lieven Meerpoel
  • Mtp inhibiting aryl piperydines or piperazines substituted with 5-membered heterocycles
    Publication number: 20070191383
    Abstract: The present invention is concerned with novel aryl piperidine or piperazine compounds substituted with certain 5-membered heterocycles having apoB secretion/MTP inhibiting activity and concomitant lipid lowering activity. The invention further relates to methods for preparing such compounds, pharmaceutical compositions comprising said compounds as well as the use of said compounds as a medicine for the treatment of hyperlipidemia, obesity and type II diabetes. The invention further relates to methods for preparing such compounds, pharmaceutical compositions comprising said compounds as well as the use of said compounds as a medicine for the treatment of atherosclerosis, pancreatitis, obesity, hyper-triglyceridemia, hypercholesterolemia, hyperlipidemia, diabetes and type II diabetes.
    Type: Application
    Filed: March 7, 2005
    Publication date: August 16, 2007
    Inventors: Lieven Meerpoel, Leo Backx, Libuse Jaroskova, Peter Roevens, Louis Van Der Veken, Marcel Viellevoye, Joannes Linders
  • Polyarylcarboxamides useful as lipid lowering agents
    Patent number: 7253157
    Abstract: Polyarylcarboxamide compounds of formula (I) are useful as lipid lowering agents.
    Type: Grant
    Filed: June 26, 2006
    Date of Patent: August 7, 2007
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Lieven Meerpoel, Peter Walter Maria Roevens, Leo Jacobus Jozef Backx, Louis Jozef Elisabeth Van der Veken, Marcel Viellevoye
  • Biphenylcarboxamides useful as lipid lowering agents
    Patent number: 7244848
    Abstract: Biphenylcarboxamide compounds of formula (I) methods for preparing such compounds, pharmaceutical compositions comprising said compounds as well as the use of said compounds as a medicine for the treatment of hyperlipidemia, obesity and type II diabetes.
    Type: Grant
    Filed: January 24, 2006
    Date of Patent: July 17, 2007
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Lieven Meerpoel, Leo Jacobs Jozef Backx
  • SULFONYL-DERIVATIVES AS NOVEL INHIBITORS OF HISTONE DEACETYLASE
    Publication number: 20070142393
    Abstract: This invention comprises the novel compounds of formula (I) wherein n, m, t, R1, R2, R3, R4, L, Q, X, Y, Z and have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
    Type: Application
    Filed: January 30, 2007
    Publication date: June 21, 2007
    Inventors: Kristof Emelen, Janine Arts, Leo Backx, Hans De Winter, Sven Van Brandt, Marc Verdonck, Lieven Meerpoel, Isabelle Pilatte, Virginie Poncelet, Alexey Dyatkin, Jimmy Van heusden
  • Sulfonyl-Derivatives as novel inhibitors of histone deacetylase
    Patent number: 7205304
    Abstract: This invention comprises the novel compounds of formula (I) wherein n, m, t, R1, R2, R3, R4, L, Q, X, Y, Z and have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine
    Type: Grant
    Filed: March 11, 2003
    Date of Patent: April 17, 2007
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Kristof Van Emelen, Janine Arts, Leo Jacobus Jozef Backx, Hans Louis Jos De Winter, Sven Franciscus Anna Van Brandt, Marc Gustaaf Celine Verdonck, Lieven Meerpoel, Isabelle Noëlle Constance Pilatte, Virginie Sophie Poncelet, Alexey Borisovich Dyatkin, Jimmy Arnold Viviane Van heusden
  • POLYARYLCARBOXAMIDES USEFUL AS LIPID LOWERING AGENTS
    Publication number: 20070082888
    Abstract: Polyarylcarboxamide compounds of formula (I) are useful as lipid lowering agents.
    Type: Application
    Filed: October 20, 2006
    Publication date: April 12, 2007
    Inventors: LIEVEN Meerpoel, Peter Roevens, Leo Backx, Louis Van der Veken, Marcel Viellevoye
  • Antifungal 4-substituted 5,6-dihydro-4h-pyrrolo[1,2-a][1,4] benzodiazepines
    Patent number: 7202240
    Abstract: The present invention concerns compounds for use as a medicine having the formula (I), the N-oxide forms, the salts, the quaternary amines and stereochemically isomeric forms thereof, wherein R1 represents hydrogen, C1-6 alkyl, C1-4alkylthio, C1-4alkyloxy, or halo; R2 represents hydrogen or C1-6alkyl; R3 represents phenyl substituted with halo, cyano, C1-4alkyloxy, C1-4alkylthio, C1-6alkyl, haloC1-6alkyl; 2-thienyl; or 3-thienyl, R4 represents hydrogen; or R2 and R4 form an extra bond, which are active against dermatophytes, and their preparation; it further relates to compositions comprising them, as well as their use as a medicine.
    Type: Grant
    Filed: October 17, 2001
    Date of Patent: April 10, 2007
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Terence Gilkerson, Roger John Nash, Jozel Frans Elisabetha Van Gestel, Lieven Meerpoel
  • Polyarylcarboxamides useful as lipid lowering agents
    Patent number: 7169796
    Abstract: Polyarylcarboxamide compounds of formula I) are useful as lipid lowering agents.
    Type: Grant
    Filed: January 5, 2005
    Date of Patent: January 30, 2007
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Lieven Meerpoel, Peter Walter Maria Roevens, Leo Jacobus Jozef Backx, Louis Jozef Elisabeth Van der Veken, Marcel Viellevoye
  • Biphenylcarboxamides useful as lipid lowering agents
    Patent number: 7135586
    Abstract: Biphenylcarboxamide compounds of formula (I) methods for preparing such compounds, pharmaceutical compositions comprising said compounds as well as the use of said compounds as a medicine for the treatment of hyperlipidemia, obesity and type II diabetes.
    Type: Grant
    Filed: November 15, 2001
    Date of Patent: November 14, 2006
    Assignee: Janssen Pharmaceutica, NV
    Inventors: Lieven Meerpoel, Leo Jacobs Jozef Backx
  • Polyarylcarboxamides useful as lipid lowering agents
    Publication number: 20060241113
    Abstract: Polyarylcarboxamide compounds of formula (I) are useful as lipid lowering agents.
    Type: Application
    Filed: June 26, 2006
    Publication date: October 26, 2006
    Inventors: Lieven Meerpoel, Peter Roevens, Leo Backx, Louis Van der Veken, Marcel Viellevoye
  • Biphenylcarboxamides useful as lipid lowering agents
    Publication number: 20060128972
    Abstract: Biphenylcarboxamide compounds of formula (I) methods for preparing such compounds, pharmaceutical compositions comprising said compounds as well as the use of said compounds as a medicine for the treatment of hyperlipidemia, obesity and type II diabetes.
    Type: Application
    Filed: January 24, 2006
    Publication date: June 15, 2006
    Inventors: Lieven Meerpoel, Leo Backx
  • Biphenylcarboxamides useful as lipid lowering agents
    Publication number: 20060128973
    Abstract: Biphenylcarboxamide compounds of formula (I) methods for preparing such compounds, pharmaceutical compositions comprising said compounds as well as the use of said compounds as a medicine for the treatment of hyperlipidemia, obesity and type II diabetes.
    Type: Application
    Filed: January 24, 2006
    Publication date: June 15, 2006
    Inventors: Lieven Meerpoel, Leo Jacobs Jozef Backx
  • N-aryl piperidine substituted biphenylcarboxamides as inhibitors of apolipoprotein b secretion
    Publication number: 20060040989
    Abstract: N-aryl piperidine substituted biphenylcarboxamides compounds of formula (I) methods for preparing such compounds, pharmaceutical compositions comprising said compounds as well as the use of said compounds as a medicine for the treatment of hyperlipidemia, obesity and type II diabetes.
    Type: Application
    Filed: August 5, 2003
    Publication date: February 23, 2006
    Inventors: Lieven Meerpoel, Leo Backx, Peter Roevens