Abstract: An array substrate, a display panel and a manufacturing method thereof are provided. The array substrate includes data lines, gate lines, a gate driving structure electrically connected with the gate lines and the gate driving signal lines, gate driving signal lines and a data fanout wiring region. The array substrate further includes a dummy fanout wiring region, a dummy pad region and a bended line, the data fanout wiring region and the dummy fanout wiring region are located at both sides of the display region, the data lines are electrically connected with pads in the dummy pad region through the wires in the dummy fanout wiring region; the gate driving signal lines are electrically connected with pads in the dummy pad region; a transmission line is disposed at one side of the gate driving structure away from the display region and electrically connected with the bended line.

Abstract: An array substrate includes a driving circuit arranged on the base substrate, and the driving circuit includes a pull-up node control circuit, a first pull-down node control circuit, and an output circuit; the pull-up node control circuit controls a potential of the pull-up node; the first pull-down node control circuit controls to write a first control voltage provided by the first control voltage line into the first pull-down node; the output circuit controls the driving signal output terminal to output a driving signal under the control of the potential of the pull-up node; the array substrate also includes a first conductive portion arranged on the base substrate; the first conductive portion is electrically connected to the first control voltage line.

Abstract: The present disclosure provides methods, compositions, kits, and systems useful in the determination and evaluation of the immune repertoire using genomic DNA from a biological sample. In one aspect, target-specific primer panels provide for the effective amplification of sequences of T cell receptor and/or B cell receptor chains with improved sequencing accuracy and resolution over the repertoire. Nucleic acid sequences of variable regions associated with the immune cell receptor are determined to effectively portray clonal diversity of a biological sample and/or differences associated with the immune cell repertoire of a biological sample.

Abstract: The present disclosure provides methods, compositions, kits, and systems useful in the determination and evaluation of the immune repertoire. In one aspect, target-specific primer panels provide for the effective amplification of sequences of T cell receptor and/or B cell receptor chains with improved sequencing accuracy and resolution over the repertoire. Variable regions associated with the immune cell receptor are resolved to effectively portray clonal diversity of a biological sample and/or differences associated with the immune cell repertoire of a biological sample.

Abstract: The present invention relates to the field of biotechnologies. Disclosed are an enzyme composition for preparing ?-nicotinamide mononucleotide (NMN), and an application thereof. In the present invention, by using adenosine and nicotinamide as raw materials, D-ribose 1-phosphate and a nicotinamide ribose intermediate are generated under enzyme catalysis of an enzyme composition of a PNP enzyme and an NRK enzyme, and finally NMN is obtained; only two enzymes need to be involved in the whole reaction system, and the by-product adenine can be recycled. Moreover, only one molecule of ATP needs to be consumed for generating one molecule of NMN, thereby greatly reducing the process cost. The reaction of synthesizing NMN by NRK enzyme catalysis in the last step is irreversible, and thus, the substrate conversion rate can be greatly improved and the production cost can be further reduced.

Abstract: The present disclosure provides methods, compositions, kits, and systems useful in the determination and evaluation of the immune repertoire. In one aspect, target-specific primer panels provide for the effective amplification of sequences of T cell receptor and/or B cell receptor chains with improved sequencing accuracy and resolution over the repertoire. Variable regions associated with the immune cell receptor are resolved to effectively portray clonal diversity of a biological sample and/or differences associated with the immune cell repertoire of a biological sample.

Abstract: Embodiments of the present disclosure provide a display panel and a display device. The display panel includes: a first substrate; at least one underlaying structure, arranged on the first substrate and in a non-display region of at least one side of a display region of the display panel; and at least one supporting structure, arranged on one side, facing away from the first substrate, of the at least one underlaying structure, where an orthographic projection of the supporting structure on the first substrate is within a range of an orthographic projection of the underlaying structure on the first substrate.

Abstract: Embodiments of the present disclosure provide a display panel and a display device. The display panel includes: a first substrate; at least one underlaying structure, arranged on the first substrate and in a non-display region of at least one side of a display region of the display panel; and at least one supporting structure, arranged on one side, facing away from the first substrate, of the at least one underlaying structure, where an orthographic projection of the supporting structure on the first substrate is within a range of an orthographic projection of the underlaying structure on the first substrate.

Abstract: Embodiments of the present disclosure provide a display panel and a display device. The display panel includes: a first substrate; at least one underlaying structure, arranged on the first substrate and in a non-display region of at least one side of a display region of the display panel; and at least one supporting structure, arranged on one side, facing away from the first substrate, of the at least one underlaying structure, where an orthographic projection of the supporting structure on the first substrate is within a range of an orthographic projection of the underlaying structure on the first substrate.

Abstract: Embodiments of the present disclosure provide a display panel and a display device. The display panel includes: a first substrate; at least one underlaying structure, arranged on the first substrate and in a non-display region of at least one side of a display region of the display panel; and at least one supporting structure, arranged on one side, facing away from the first substrate, of the at least one underlaying structure, where an orthographic projection of the supporting structure on the first substrate is within a range of an orthographic projection of the underlaying structure on the first substrate.

Abstract: The present disclosure provides methods, compositions, kits, and systems useful in the determination and evaluation of the immune repertoire. In one aspect, target-specific primer panels provide for the effective amplification of sequences of B cell receptor chains with improved sequencing accuracy and resolution over the repertoire. Variable regions associated with the immune cell receptor are resolved to effectively portray clonal diversity of a biological sample and/or differences associated with the immune cell repertoire of a biological sample.

Abstract: Embodiments of the present disclosure provide a display panel and a display device. The display panel includes: a first substrate; at least one underlaying structure, arranged on the first substrate and in a non-display region of at least one side of a display region of the display panel; and at least one supporting structure, arranged on one side, facing away from the first substrate, of the at least one underlaying structure, where an orthographic projection of the supporting structure on the first substrate is within a range of an orthographic projection of the underlaying structure on the first substrate.

Abstract: In accordance with some embodiments of the disclosure, an array substrate and a related liquid crystal display device are provided. The array substrate can include a plurality of pixel electrodes arranged on a base substrate, and a conductive opaque line arranged between two neighboring pixel electrodes and overlapping with each of the two neighboring pixel electrodes along a width direction of the conductive opaque line.

Abstract: There are provided a color filter substrate and a display apparatus. The color filter substrate comprises a base substrate; a black matrix; a first color filter; a planarization layer, which is located between the base substrate and the black matrix and has an opening; and a first color cast compensation layer, which is located in the opening of the planarization layer, wherein a light of a first color passes through the first color filter in a direction deviating from the vertical direction of the base substrate at an angle a, the first color cast compensation layer at least partly converts the light of the first color passing through the first color filter to a light of a second color or a light of a third color, and the angle a is greater than or equal to 0 degree and less than 90 degrees.

Abstract: A horizontal electric field type display panel, a method of manufacturing the same, and a display device are provided in embodiments of the disclosure, the horizontal electric field type display panel including: a first substrate and a second substrate arranged opposite to each other; a liquid crystal layer between the first substrate and the second substrate; and a first compensation film layer between the first substrate and the second substrate, wherein the first compensation film layer is configured to compensate for a phase delay of an axial light in a condition that the display panel is subjected to a non-uniform external force.

Abstract: The present disclosure provides methods, compositions, kits, and systems useful in the determination and evaluation of the immune repertoire using genomic DNA from a biological sample. In one aspect, target-specific primer panels provide for the effective amplification of sequences of T cell receptor and/or B cell receptor chains with improved sequencing accuracy and resolution over the repertoire. Nucleic acid sequences of variable regions associated with the immune cell receptor are determined to effectively portray clonal diversity of a biological sample and/or differences associated with the immune cell repertoire of a biological sample.

Abstract: The present disclosure provides methods, compositions, kits, and systems useful in the determination and evaluation of the immune repertoire. In one aspect, target-specific primer panels provide for the effective amplification of sequences of T cell receptor and/or B cell receptor chains with improved sequencing accuracy and resolution over the repertoire. Variable regions associated with the immune cell receptor are resolved to effectively portray clonal diversity of a biological sample and/or differences associated with the immune cell repertoire of a biological sample.

Abstract: The present disclosure provides methods, compositions, kits, and systems useful in the determination and evaluation of the immune repertoire using genomic DNA from a biological sample. In one aspect, target-specific primer panels provide for the effective amplification of sequences of T cell receptor and/or B cell receptor chains with improved sequencing accuracy and resolution over the repertoire. Nucleic acid sequences of variable regions associated with the immune cell receptor are determined to effectively portray clonal diversity of a biological sample and/or differences associated with the immune cell repertoire of a biological sample.

Abstract: The present disclosure provides methods, compositions, kits, and systems useful in the determination and evaluation of the immune repertoire. In one aspect, target-specific primer panels provide for the effective amplification of sequences of T cell receptor and/or B cell receptor chains with improved sequencing accuracy and resolution over the repertoire. Variable regions associated with the immune cell receptor are resolved to effectively portray clonal diversity of a biological sample and/or differences associated with the immune cell repertoire of a biological sample.

Abstract: A horizontal electric field type display panel, a method of manufacturing the same, and a display device are provided in embodiments of the disclosure, the horizontal electric field type display panel including: a first substrate and a second substrate arranged opposite to each other; a liquid crystal layer between the first substrate and the second substrate; and a first compensation film layer between the first substrate and the second substrate, wherein the first compensation film layer is configured to compensate for a phase delay of an axial light in a condition that the display panel is subjected to a non-uniform external force.