Abstract: A CpG oligonucleotide and use of the CpG oligonucleotide are described. The CpG oligonucleotide has TLR9 agonist activity.

Abstract: According to embodiments, an energy storage device (ESD) holder includes a main body, one or more ESD openings in the main body, and one or more vacancy regions in the main body. Each of the one or more vacancy regions is operable to hold a fluid. A first ESD opening of the one or more ESD openings is operable to prevent the fluid from contacting an ESD within the first ESD opening.

Abstract: An energy storage device (ESD) system includes a battery module that includes individual cases. Each of the individual cases includes a battery cell. The ESD system further includes an ESD pump and a battery management system (BMS). The ESD pump is operable to flow immersion fluid into, through, and out of the battery module and the individual cases. The BMS is operable to make a determination that a status of the battery cell is out-of-range, and, responsive to the determination that the status of the battery cell is out-of-range, control operations of the ESD pump.

Abstract: A system for conditioning air, the system having: a controller; an energy storage system (ESS) that is a battery, wherein the ESS is operable to power the system; and an AC power bus for connecting the system to an AC power grid to selectively charge the ESS; wherein the controller is configured to: request, from the ESS, health state data of the ESS; determine a health state of the ESS from the health state data; and request a replacement ESS responsive to the health state of the ESS.

Abstract: An air conditioning system having: a controller; an energy storage device including a battery pack, wherein the energy storage device is operable to power the air conditioning system; and an AC power bus for connection the air conditioning system to an AC power grid to selectively charge the battery pack; wherein the controller is configured to: receive a request to charge or discharge the battery pack within a time window; determine whether the battery pack will remain within a predetermined operating temperature range while being charged or discharged within the time window, and responsive to a determination, either charging or discharging the battery pack, pursuant to the request, or denying the request.

Abstract: An energy system having: a heating, ventilation and/or air conditioning (HVAC) system that includes an HVAC branch loop with an HVAC conditioning flow that flows in one direction or bidirectionally; a battery energy storage system (ESS) that includes a battery pack, having batteries, configured for an operating temperature within a target temperature range, an ESS conditioning loop with an ESS conditioning flow, wherein the ESS conditioning loop is thermally coupled to the battery pack, and the HVAC branch loop and the ESS conditioning loop are fluidly isolated from each other; a heat exchanger, wherein the HVAC branch loop and the ESS conditioning loop are thermally coupled to each other via the heat exchanger; and a controller configured to control flow within the HVAC branch loop and the ESS conditioning loop such that the battery pack operates within the target temperature range.

Abstract: Provided are an immunomodulatory CpG ODN chemically modified by means of a structure as shown by general formula I and the use thereof. The CpG ODN has an immunostimulatory activity, can stimulate the proliferation of B cells, and produce specific cytokines. The above-mentioned CpG ODN can be used as a vaccine adjuvant alone or in combination with other adjuvants to exert a synergistic effect, and can also be used in the preparation of drugs for preventing or treating tumors, infections, and allergies.

Abstract: The disclosure provides a composition comprising CpG ODN and one or more other adjuvants that work together with the immunomodulatory CpG ODN, such as an aluminum adjuvant, wherein the CpG ODN comprises or consists of a nucleotide sequence selected from SEQ ID NOs: 1-4, wherein at least one nucleotide in the nucleotide sequence is a chemically modified nucleotide having a structure of formula (I): wherein, Y is S or O, R is H or a positively charged counterion, B is independently an unmodified or modified nucleobase, and R1 is H, F, CI, OH, OMe, Me, O-ethyloxymethyl. Use of the composition, a pharmaceutical composition comprising the composition, a preparation method thereof, and use of the pharmaceutical composition are also disclosed.

Abstract: Methods for providing power to electronic components (e.g., servers in a datacenter, or other devices) can include providing AC power received from an external source to the devices. During periods of high demand, when costs of external AC power exceed a threshold, or when availability of external AC power is decreased, distributed backup power supply systems can be utilized to temporarily offset or to reverse consumption of external AC power. Such distributed backup power systems can be periodically recharged during periods of low power demand, and thus consistently retain adequate charge for backup use in the event of power loss.

Abstract: Provided are an immunomodulatory CpG ODN chemically modified by means of a structure as shown by general formula I and the use thereof. The CpG ODN has an immunostimulatory activity, can stimulate the proliferation of B cells, and produce specific cytokines. The above-mentioned CpG ODN can be used as a vaccine adjuvant alone or in combination with other adjuvants to exert a synergistic effect, and can also be used in the preparation of drugs for preventing or treating tumors, infections, and allergies.

Abstract: Methods and systems for rerating a battery pack based on fuel gauge data are described, including capturing operational or fuel gauge data for a first battery pack that contains a plurality of battery cells, and determining, based on the fuel gauge data, a remaining capacity of the first battery pack. When the remaining capacity of the first battery pack falls below the minimum capacity; a new battery pack can be configured using some or all of the battery cells, and a second fuel gauge can be configured with new initial capacity and minimum capacity ratings.

Abstract: Methods for redeploying used battery units can include capturing performance data of an energy storage unit containing a battery unit at the end of its useful life for a primary application, and determining, based on the performance data, a remaining energy output capacity. If the battery unit meets or exceeds threshold performance criteria, the battery unit can be incorporated into a second energy storage unit and reconfigured to reflect the remaining energy output capacity. The second storage unit can include the redeployed battery unit alone, or in combination with any suitable number of additional battery units.

Abstract: Methods and systems for controlling distribution of a main power supply and backup power supply can include detecting an output load on the main power supply from one or more electronic devices in excess of a threshold, which may correspond to a high efficiency band of the main power supply, and causing a backup power supply to provide an amount of supplemental power to the one or more electronic devices based in part on a difference between the output load and the threshold.

Abstract: A power supply system can include a plurality of battery backup units and a control unit. The battery backup units may be utilized to supply backup energy to a power supply unit, for example, in case of a power outage event. The control unit can gauge a respective capacity, temperature, age, and/or other characteristic of each respective battery backup unit of the plurality of battery backup units. The control unit can designate a particular battery backup unit of the plurality of battery backup units as a spared unit, e.g., to be spared in the power outage event. The designation may be based at least in part on the respective capacity or other characteristic of each respective battery backup unit gauged.

Abstract: Information about firmware modules for a power unit (e.g., a battery backup unit or a power supply unit) can be downloaded, along with the firmware modules themselves. The firmware modules, which may constitute less than a complete firmware re-flash, can be used to update firmware of the power unit from a first version type to a second version type.

Abstract: A method for managing backup power in the event of a power supply deficit or disruption includes detecting the power supply deficit and recruiting some or all of the backup battery units associated with electronic devices in the system to provide a backup power supply. Depending on the severity of the power supply failure, the selected backup battery units can be reconfigured from providing power to local electronic devices to providing power along a backup power supply pathway to other electronic components in the system.

Abstract: Calibrating a battery capacity gage employs a controlled discharge of a backup battery unit. A method of updating a capacity gage includes charging a backup battery unit to a predetermined high charge level. A first amount of energy is discharged from the backup battery unit at a first controlled discharge rate so as to discharge the backup battery unit from the predetermined high charge level to a first low charge level. The backup battery unit is charged back to the predetermined high charge level. A power system controller estimates, based on the first amount of energy and the first controlled discharge rate, a second amount of energy that can be discharged from the backup battery unit at a second controlled discharge rate greater than the first controlled discharge rate. The capacity gage is updated based on the second amount of energy estimated by the power system controller.

Abstract: Systems for controlling cycling operations for backup battery units in a datacenter include groups of backup battery units and power supply units that can supply power to datacenter components from either a primary power supply or, the backup battery units. Each group of multiple battery units has sufficient capacity to provide backup power to a respective electronic device even when one battery unit is offline. In operation, a controller receives requests to perform cycling operations, e.g. maintenance, on the backup batteries. Upon each request, the system retrieves status information corresponding to each backup battery unit and determines whether the remainder of the backup battery units can supply sufficient power to meet or exceed power demand, and either allow or prevent each backup battery unit from performing the cycling operation in response to determining whether the remainder of the backup battery units can or cannot supply sufficient power.

Abstract: Methods and related systems conduct a capacity check of a battery via a partial discharge cycle. A method of estimating a total capacity of a battery includes partially discharging the battery at a controlled discharge rate so as to discharge an amount of energy from the battery over a period of time. An output voltage of the battery is measured during the period of time. A total capacity of the battery is estimated based on the amount of energy discharged from the battery during the partial discharge cycle and the output voltage of the battery measured during the partial discharge cycle.

Abstract: A power supply system can include a plurality of battery backup units and a control unit. The battery backup units may be utilized to supply backup energy to a power supply unit, for example, in case of a power outage event. The control unit can gauge a respective capacity, temperature, age, and/or other characteristic of each respective battery backup unit of the plurality of battery backup units. The control unit can designate a particular battery backup unit of the plurality of battery backup units as a spared unit, e.g., to be spared in the power outage event. The designation may be based at least in part on the respective capacity or other characteristic of each respective battery backup unit gauged.