Patents by Inventor Lih-Hwa HWANG

Lih-Hwa HWANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SINDBIS VIRUS DNA-BASED VACCINE
    Publication number: 20220401548
    Abstract: Provided is a vaccine composition including a recombinant DNA vaccine against a pathogen. The recombinant DNA vaccine includes an expression cassette operably linked to a promoter, and the expression cassette encodes a non-structural protein of a Sindbis virus and an antigenic protein of the pathogen. Also provided is a method of producing a protective immune response against a pathogen in a subject in need thereof by administering the vaccine composition to the subject.
    Type: Application
    Filed: June 17, 2022
    Publication date: December 22, 2022
    Applicant: National Yang Ming Chiao Tung University
    Inventors: Chia-Lin HSU, Lih-Hwa Hwang, Jian Wen Heng
  • TREATMENT OF CELLULAR PROLIFERATIVE DISORDERS
    Publication number: 20150313963
    Abstract: Disclosed are composition and methods for treating cellular proliferative disorders.
    Type: Application
    Filed: May 5, 2015
    Publication date: November 5, 2015
    Inventors: Lih-Hwa Hwang, Kai-Wen Huang
  • ACOUSTICALLY DELIVERING METHODS AND COMPOSITONS FOR REMOTE TREATMENT OF A TUMOR
    Publication number: 20100092395
    Abstract: Disclosed herein is a method of acoustically delivering a therapeutic composition to a subject pre-diagnosed with a tumor. The method comprises the steps of: parenterally administering the composition from a site remote from a tumor location; and exposing the parenterally administering site to ultrasound waves to target the delivery of the composition. The therapeutic composition comprises an effective amount of a polypeptide or a plasmid nucleic acid encoding the polypeptide, the polypeptide or the nucleic acid is suspended in a dispersed medium; and an effective amount of an microbubble contrast agent; wherein the polypeptide is an angiogenesis inhibitor, and the therapeutic composition is capable of reducing the size of the tumor without the risk of inducing viral vector-induced immunogenicity in the subject.
    Type: Application
    Filed: August 16, 2009
    Publication date: April 15, 2010
    Applicant: NATIONAL TAIWAN UNIVERSITY
    Inventors: Lih-Hwa HWANG, Wen-Shiang CHEN
  • Treatment of cellular proliferative disorders
    Publication number: 20090053171
    Abstract: Disclosed are composition and methods for treating cellular proliferative disorders.
    Type: Application
    Filed: August 22, 2008
    Publication date: February 26, 2009
    Inventors: Lih-Hwa Hwang, Kai-Wen Huang