Patents by Inventor Lihe Zhang

Lihe Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240085035
    Abstract: An air guide ring for an air conditioner outdoor unit is provided. The air guide ring includes an air guide ring body. An air guide channel is defined in the air guide ring body. The air guide ring body includes a first limiting portion and a second limiting portion. The first limiting portion and the second limiting portion are configured to fit with a fixing member of the air conditioner outdoor unit and to implement bi-directional limiting, so as to prevent inward contraction deformation and outward expansion deformation of the air guide ring body from occurring.
    Type: Application
    Filed: November 24, 2023
    Publication date: March 14, 2024
    Applicants: GD MIDEA HEATING & VENTILATING EQUIPMENT CO., LTD., HEFEI MIDEA HEATING & VENTILATING EQUIPMENT CO., LTD.
    Inventors: Mingren WANG, Dongdong YU, Shengsheng LIAO, Langshui HUANG, Ruhui LI, Weihong LUO, Tao ZHANG, Lihe CHEN
  • Patent number: 11510974
    Abstract: The present invention relates to a mutated virus. Said virus can be an influenza virus of human or other animal origin. The present invention also relates to a method for preparing the mutated virus, the method comprising introducing UAG codons into positions upstream of the stop codons per se of one or more genes of a viral genome by reverse genetic techniques. The present invention further relates to uses of the mutated virus, for example, as a live attenuated vaccine, or in replication of controllable and safe virus models, and the like.
    Type: Grant
    Filed: August 2, 2016
    Date of Patent: November 29, 2022
    Assignee: PEKING UNIVERSITY
    Inventors: Demin Zhou, Longlong Si, Xueying Zhou, Ziwei Zhang, Huan Xu, Zhenyu Tian, Chuanling Zhang, Sulong Xiao, Qing Xia, Lihe Zhang
  • Publication number: 20200268870
    Abstract: The present invention relates to a mutated virus. Said virus can be an influenza virus of human or other animal origin. The present invention also relates to a method for preparing the mutated virus, the method comprising introducing UAG codons into positions upstream of the stop codons per se of one or more genes of a viral genome by reverse genetic techniques. The present invention further relates to uses of the mutated virus, for example, as a live attenuated vaccine, or in replication of controllable and safe virus models, and the like.
    Type: Application
    Filed: August 2, 2016
    Publication date: August 27, 2020
    Inventors: Demin Zhou, Longlong Si, Xueying Zhou, Ziwei Zhang, Huan Xu, Zhenyu Tian, Chuanling Zhang, Sulong Xiao, Qing Xia, Lihe Zhang
  • Patent number: 10087217
    Abstract: The present invention relates to an adeno-associated virus with site-directed mutagenesis and site-specific modification, and a preparation method and uses thereof. Specifically, the present invention uses genetic code expansion techniques to incorporate non-natural amino acid into an adeno-associated virus capsid protein VP1 or fragment thereof, thereby obtaining an adeno-associated virus with site-directed mutagenesis using the non-natural amino acid. The adeno-associated virus with site-directed mutagenesis is equivalent to a wild-type virus in terms of production, transduction and mobility, can couple with other functional molecules, such as targeting molecules, and can carry a functional gene in a normal manner, which indicates that the adeno-associated virus with site-directed mutagenesis can be used as a tool adeno-associated virus, and applied in various aspects associated with adeno-associated virus such as finding adeno-associated virus binding proteins or using as target genetic therapy vector.
    Type: Grant
    Filed: October 30, 2014
    Date of Patent: October 2, 2018
    Assignee: Peking University
    Inventors: Demin Zhou, Chuanling Zhang, Sulong Xiao, Tianzhuo Yao, Yongxiang Zheng, Fei Yu, Longlong Si, Lihe Zhang
  • Patent number: 9920088
    Abstract: The present invention relates to the use of triterpenoid derivatives for the preparation of a medicament for preventing or treating influenza diseases, in which the substituents are as defined in the specification. The triterpenoid derivatives of the present invention have obvious inhibition effect on influenza virus, and are capable of obviously preventing influenza virus from entering cells, and can be used for preventing or treating influenza.
    Type: Grant
    Filed: October 18, 2013
    Date of Patent: March 20, 2018
    Assignee: University of Macao
    Inventors: Demin Zhou, Maorong Yu, Sulong Xiao, Fei Yu, Yiyun Peng, Yunyan Qiu, Lihe Zhang, Yitao Wang
  • Publication number: 20160297855
    Abstract: The present invention relates to an adeno-associated virus with site-directed mutagenesis and site-specific modification, and a preparation method and uses thereof. Specifically, the present invention uses genetic code expansion techniques to incorporate non-natural amino acid into an adeno-associated virus capsid protein VP1 or fragment thereof, thereby obtaining an adeno-associated virus with site-directed mutagenesis using the non-natural amino acid. The adeno-associated virus with site-directed mutagenesis is equivalent to a wild-type virus in terms of production, transduction and mobility, can couple with other functional molecules, such as targeting molecules, and can carry a functional gene in a normal manner, which indicates that the adeno-associated virus with site-directed mutagenesis can be used as a tool adeno-associated virus, and applied in various aspects associated with adeno-associated virus such as finding adeno-associated virus binding proteins or using as target genetic therapy vector.
    Type: Application
    Filed: October 30, 2014
    Publication date: October 13, 2016
    Applicant: Peking University
    Inventors: Demin Zhou, Chuanling Zhang, Sulong Xiao, Tianzhuo Yao, Yongxiang Zheng, Fei Yu, Longlong Si, Lihe Zhang
  • Patent number: 9367762
    Abstract: An image processing device and a method performed by a computer, the image processing device comprising: a processing unit configured to operate as an image acquisition unit configured to acquire an image; a similarity map generator configured to calculate, with a region constructed with one or a plurality of pixels in the image as a constituent unit, a first similarity map based on a first algorithm, the first similarity map representing a degree of similarity between the region and a marginal region of the image, and calculate a second similarity map based on a second algorithm, the second similarity map representing a degree of similarity between the region and the marginal region of the image; and a saliency map generator configured to integrate the first similarity map and the second similarity map to generate a saliency map.
    Type: Grant
    Filed: November 24, 2014
    Date of Patent: June 14, 2016
    Assignee: OMRON CORPORATION
    Inventors: Xiang Ruan, Huchuan Lu, Lihe Zhang, Xiaohui Li
  • Publication number: 20150274766
    Abstract: The present invention relates to the use of triterpenoid derivatives for the preparation of a medicament for preventing or treating influenza diseases, in which the substituents are as defined in the specification.
    Type: Application
    Filed: October 18, 2013
    Publication date: October 1, 2015
    Inventors: Demin Zhou, Maorong Yu, Sulong Xiao, Fei Yu, Yiyun Peng, Yunyan Qiu, Lihe Zhang
  • Publication number: 20150154471
    Abstract: An image processing device and a method performed by a computer, the image processing device comprising: a processing unit configured to operate as an image acquisition unit configured to acquire an image; a similarity map generator configured to calculate, with a region constructed with one or a plurality of pixels in the image as a constituent unit, a first similarity map based on a first algorithm, the first similarity map representing a degree of similarity between the region and a marginal region of the image, and calculate a second similarity map based on a second algorithm, the second similarity map representing a degree of similarity between the region and the marginal region of the image; and a saliency map generator configured to integrate the first similarity map and the second similarity map to generate a saliency map.
    Type: Application
    Filed: November 24, 2014
    Publication date: June 4, 2015
    Applicant: OMRON Corporation
    Inventors: Xiang Ruan, Huchuan Lu, Lihe Zhang, Xiaohui Li