Abstract: A composition for glass, and aluminosilicate glass, preparation method therefor, and use thereof. In molar percentage, in the composition, the total content of SiO2, B2O3, P2O5, GeO2 and TeO2 is 60˜85 mol %; the total content of Al2O3 and Ga2O3 is 3˜20 mol %; the total content of ZnO and Y2O3 is 0.1˜5 mol %; and the total content of alkaline earth metal oxide is 4˜30 mol %. The glass has a high strain point, a low melting temperature, and a high thermal expansion coefficient, has good toughness, and is suitable for large-scale industrial production.

Abstract: A method of using a catheter assembly for inserting in a fluid filled space in a body includes providing a main body having a first end portion and a second end portion. The first end portion is positioned within the fluid filled space. The second end portion is adjusted to extend outwardly from the fluid filled space when the first end portion is positioned within the fluid filled space. A catheter tip is connected to the second end portion of the main body. The catheter tip includes a housing having a cavity defined therein and a rotating element positioned within the fluid filled space. The rotating element is rotated within the cavity of the housing to impart movement of the first end portion of the main body within the fluid filled space.

Abstract: Systems and methods for stereo-polarimetric compressed-sensing ultrafast imaging.

Abstract: Among the various aspects of the present disclosure is the provision of systems and methods of velocity-matched ultrasonic tagging in photoacoustic flowgraphy.

Abstract: Among the various aspects of the present disclosure is the provision of systems and methods of imaging using photoacoustic computed tomography.

Abstract: A photoacoustic medical-imaging device includes a wavelength conversion assembly (108) configured for outputting laser pulses at a targeted wavelength. It also includes a photoacoustic probe configured for acoustic coupling to a patient, for directing the pulses, and for acquiring, in response, radiofrequency data for photoacoustic imaging. It may include an optical fiber bundle (120) that comprises an optical fiber having an input end, and be configured for illuminating, with a homogenous beam, so as to conform to an acceptance angle (160) of the fiber at that end. It may also include a light collimator, and a diffuser for receiving the outputted laser pulses from the collimator. The diffuser may be configured for spreading a focus of the pulsed light (148) over an input aperture of the bundle to equalize the light received by different constituent optical fibers of the bundle. The assembly may include a dye cell (132), and may reside in the device.

Abstract: A photonic molecule laser is described that includes a photonic molecule waveguide coupled to a photonic molecule seeding source configured to deliver a plurality of photonic molecules. The photonic molecule waveguide includes a second dopant maintained at a population inverted state with an energy level transition corresponding to a second frequency that is an N-fold multiple of a first frequency and amplifies the number of photonic molecules via stimulated emission. The photonic molecule seeding source includes a waveguide with a first dopant maintained at a population inverted state with an energy level transition corresponding to the first frequency. A pump source is coupled to the waveguide configured to deliver a first frequency laser pulse with pulse coherence time less than the photonic molecules correlation time. Each photonic molecule includes a threshold bound state of N first frequency photons, and each photonic molecule has the second frequency.

Abstract: Systems and methods for improving limited-view photoacoustic tomography using an acoustic reflector are described. In particular, an acoustic reflector and ultrasonic transducer array are integrated to provide a virtual array that enhances the field of view of the ultrasonic transducer array, thereby improving the quality of photoacoustic tomography images obtained using the systems and methods described herein.

Abstract: A breakaway connector generally includes a first valve having a first rotating-type fluid control member, and a second valve that is attachable to the first valve and has a second rotating-type fluid control member. Each of the fluid control members has an open position in which fluid is permitted to flow through the respective valve, and a closed position in which fluid is prevented from flowing through the respective valve. Each one of the valves is configured to engage the fluid control member of the other one of the valves to move the fluid control member from the open position to the closed position upon detachment of the valves from one another.

Abstract: The present invention relates to the field of glass manufacturing, and discloses aluminoborosilicate glass, and a preparation method and an application thereof. Based on the total weight of components in the composition of the glass, the glass comprises: 33-60 wt % SiO2, 3-10 wt % Al2O3, 10-30 wt % B2O3, 1-15 wt % ZnO+TiO2+Sc2O3, and 7-27 wt % alkali-earth oxide RO, wherein RO is at least one of MgO, CaO, SrO and BaO, and 0.001 wt %?Sc2O3?1 wt %. The aluminoborosilicate glass provided in the present invention has advantages including low density, high index of refraction, low thermal expansion coefficient, high thermostability, high flexibility, and easy bending, etc.

Abstract: Apparatus and methods for measuring infrared absorption of a sample that includes delivering a pulse of infrared radiation to a region of the sample, delivering pulses of radiation of a shorter wavelength than infrared radiation to a sub-region within the region, and using one or more properties of the induced photoacoustic signals to create a signal indicative of infrared absorption of the sub-region of the sample.

Abstract: Provided are a device for press-cutting glass, a method for press-cutting glass, and a glass-cutting system having the device for press-cutting glass. The device for press-cutting glass comprises a supporting member, having a first supporting portion and a second supporting portion for supporting a glass substrate, which are arranged in a spaced apart manner in a first direction; and a press-cutting member for press-cutting an edge of the glass substrate, which is positioned between the first supporting portion and the second supporting portion in the first direction. The device for press-cutting glass has advantages including high press-cutting efficiency, simple structure, low manufacturing cost, and easy assembling with other devices.

Abstract: Multifocal photoacoustic imaging systems and methods that implement an ergodic relay to encode photoacoustic signals detected from a plurality of illuminated optical foci regions.

Abstract: The present invention is directed toward neutralizing monoclonal antibodies to Vascular Endothelial Growth Factor (VEGF) and angiopoietin 2 (Ang-2), pharmaceutical compositions comprising same, and methods of treatment comprising administering such a pharmaceutical composition to a patient.

Abstract: A system and method for compressed-sensing ultrafast photography for two-dimensional dynamic imaging is disclosed. The system and method may capture non-repetitive time-evolving events at up to about 100 billion frames per second. In an aspect, a digital micromirror device (DMD) may be added as the spatial encoding module. By using the DMD and applying the CUP reconstruction algorithm, a conventional 1D streak camera may be transformed to a 2D ultrafast imaging device. The resultant system may capture a single, non-repetitive event at up to 100 billion frames per second with appreciable sequence depths (up to about 350 frames per acquisition). In another aspect, a dichroic mirror may be used to separate signals into two color channels, and may further expand CUP's functionality into the realm of four-dimensional x, y, ?, t ultrafast imaging, maximizing the information content that may be simultaneously acquired from a single instrument.

Abstract: Methods for measuring blood flow speed within blood vessels using a PA imaging system are disclosed. The methods include position a field of view of a PA imaging system along a section of a blood vessel, introducing a PA discontinuity into the blood flow within the blood vessel upstream of the FOV of the PA system, monitoring the movement of the PA discontinuity during movement through the FOV of the PA imaging device, and calculate the blood flow speed using at least two measured positions and corresponding times of the PA discontinuity within the FOV of the PA imaging system. PA discontinuities may include blood surges formed by compressing and releasing the blood vessel and/or boluses of a fluid with high PA contrast relative to the blood, such as saline solution.

Abstract: A single-impulse panoramic photoacoustic computed tomography (SIP-PACT) system for small-animal whole-body imaging is disclosed. In addition, a dual-speed of sound image universal back-projection reconstruction method is disclosed. Further, a PACT system for imaging a breast of a subject is disclosed.

Abstract: A method for obtaining a 3-D OR-PAM image of microvasculature within a region of interest of a subject is provided. The method includes: focusing a first light pulse at a first depth beneath a first surface position within the region of interest; receiving a first PA signal in response to the first light pulse; focusing a second light pulse at a second depth beneath the first surface position within the region of interest; receiving a second PA signal in response to the second light pulse; and forming the 3-D OR-PAM image by combining the first PA signal and the second PA signal.

Abstract: A method for fast high-resolution deep photoacoustic tomography of action potentials in brains is provided herein. The method may utilize a high-speed, high-spatial-resolution, deep-penetration photoacoustic computed tomography (PACT) system for real-time imaging of action potentials.

Abstract: A probe for use with an imaging system, including a scanning device configured to receive a first light beam from a light source, a beam-divider configured to split the first light beam into a plurality of second light beams, and a focusing device configured to focus each of the second light beams on respective locations in an object of interest is disclosed.