Patents by Inventor Lihong Wang

Lihong Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210088384
    Abstract: Among the various aspects of the present disclosure is the provision of systems and methods of compressed-sensing ultrafast spectral photography.
    Type: Application
    Filed: September 23, 2020
    Publication date: March 25, 2021
    Inventors: Lihong Wang, Peng Wang
  • Patent number: 10941204
    Abstract: The present invention is directed toward monoclonal antibodies that bind to death receptor 4 and/or death receptor 5, a pharmaceutical composition comprising same, and methods of treatment comprising administering such a pharmaceutical composition to a patient.
    Type: Grant
    Filed: October 28, 2016
    Date of Patent: March 9, 2021
    Assignee: GALAXY BIOTECH, LLC
    Inventors: Kyung Jin Kim, Hangil Park, Lihong Wang, Yi Ding, April Zhang, Maximiliano Vasquez
  • Publication number: 20210047230
    Abstract: The present disclosure relates to glass manufacturing, a glass composition, glass with a low inclusion content and a preparation method therefor and use thereof. The composition comprises 50-64 wt. % SiO2, 14-24 wt. % Al2O3, 0-7 wt. % B2O3+P2O5, 0.5-7 wt. % MgO, 1-10 wt. % CaO, 0-9 wt. % SrO, 0.1-14 wt. % BaO, 0.1-5 wt. % ZnO, 0.1-4 wt. % TiO2, 0.1-7 wt. % Y2O3+La2O3+Nd2O3, and <0.05 wt. % R2O, wherein R2O is a sum of the content of Li2O, Na2O and K2O, and the composition satisfies the following conditions: (1) a temperature T100 corresponding to a viscosity of 100 P is 1730° C. or higher; (2) a surface tension at 1300° C. is less than 420 mN/m. The glass prepared by the glass composition and the glass with a low inclusion content preparation method has the advantages of having low inclusion content, having a simple preparation process, being low in cost and so on.
    Type: Application
    Filed: November 27, 2018
    Publication date: February 18, 2021
    Applicant: TUNGHSU GROUP CO., LTD.
    Inventors: Guangtao Zhang, Qing Li, Quan Zheng, Lihong Wang, Dongcheng Yan, Junfeng Wang, Bo Wang, Zhiyong Li
  • Publication number: 20210010976
    Abstract: A photoacoustic imaging system is disclosed that includes an ergodic relay coupled optically to a light source configured to produce a light pulse and further coupled acoustically to a transducer. The ergodic relay is further configured to direct at least two PA signals to the transducer. Each of the at least two PA signals are produced at different positions within the field of view of the object to be imaged in response to illumination by a single light pulse. The transducer detects each of the at least two PA signals after each of at least two delays that correspond to the position at which each PA signal was produced.
    Type: Application
    Filed: May 10, 2018
    Publication date: January 14, 2021
    Applicant: California Institute of Technology
    Inventors: Lihong Wang, Yang Li, Lei Li
  • Publication number: 20200397523
    Abstract: Image-guided microrobotic systems, methods and methods that employ micromotor(s) having imaging agent(s) and cargo in a microcapsule, each micromotor having a partial coating over a reactive particle and/or asymmetrical geometry, when activated the microcapsule disintegrates releasing the micromotor(s) and active propulsion is generated when fluid contacts the reactive particle.
    Type: Application
    Filed: June 24, 2020
    Publication date: December 24, 2020
    Inventors: Wei Gao, Lihong Wang, Lei Li, Zhiguang Wu
  • Publication number: 20200376238
    Abstract: A method of using a catheter assembly for inserting in a fluid filled space in a body includes providing a main body having a first end portion and a second end portion. The first end portion is positioned within the fluid filled space. The second end portion is adjusted to extend outwardly from the fluid filled space when the first end portion is positioned within the fluid filled space. A catheter tip is connected to the second end portion of the main body. The catheter tip includes a housing having a cavity defined therein and a rotating element positioned within the fluid filled space. The rotating element is rotated within the cavity of the housing to impart movement of the first end portion of the main body within the fluid filled space.
    Type: Application
    Filed: August 17, 2020
    Publication date: December 3, 2020
    Inventors: Eric Leuthardt, Guy Genin, Matthew Smyth, David Limbrick, Daniel Moran, Lihong Wang, Aaron McLaughlin, Manish Shah, Alexander Yang, Samuel Stone, Devon Haydon, Michael Winek, Richard Marcus
  • Patent number: 10833469
    Abstract: A photonic molecule laser is described that includes a photonic molecule waveguide coupled to a photonic molecule seeding source configured to deliver a plurality of photonic molecules. The photonic molecule waveguide includes a second dopant maintained at a population inverted state with an energy level transition corresponding to a second frequency that is an N-fold multiple of a first frequency and amplifies the number of photonic molecules via stimulated emission. The photonic molecule seeding source includes a waveguide with a first dopant maintained at a population inverted state with an energy level transition corresponding to the first frequency. A pump source is coupled to the waveguide configured to deliver a first frequency laser pulse with pulse coherence time less than the photonic molecules correlation time. Each photonic molecule includes a threshold bound state of N first frequency photons, and each photonic molecule has the second frequency.
    Type: Grant
    Filed: October 12, 2018
    Date of Patent: November 10, 2020
    Assignee: Washington University
    Inventors: Jung-Tsung Shen, Lihong Wang
  • Publication number: 20200325062
    Abstract: A composition for glass, and aluminosilicate glass, preparation method therefor, and use thereof. In molar percentage, in the composition, the total content of SiO2, B2O3, P2O5, GeO2 and TeO2 is 60˜85 mol %; the total content of Al2O3 and Ga2O3 is 3˜20 mol %; the total content of ZnO and Y2O3 is 0.1˜5 mol %; and the total content of alkaline earth metal oxide is 4˜30 mol %. The glass has a high strain point, a low melting temperature, and a high thermal expansion coefficient, has good toughness, and is suitable for large-scale industrial production.
    Type: Application
    Filed: November 14, 2018
    Publication date: October 15, 2020
    Inventors: Qing LI, Guangtao ZHANG, Junfeng WANG, Xiaoyi WANG, Dongcheng YAN, Lihong WANG, Quan ZHENG
  • Patent number: 10773060
    Abstract: A method of using a catheter assembly for inserting in a fluid filled space in a body includes providing a main body having a first end portion and a second end portion. The first end portion is positioned within the fluid filled space. The second end portion is adjusted to extend outwardly from the fluid filled space when the first end portion is positioned within the fluid filled space. A catheter tip is connected to the second end portion of the main body. The catheter tip includes a housing having a cavity defined therein and a rotating element positioned within the fluid filled space. The rotating element is rotated within the cavity of the housing to impart movement of the first end portion of the main body within the fluid filled space.
    Type: Grant
    Filed: November 30, 2015
    Date of Patent: September 15, 2020
    Assignee: Washington University
    Inventors: Eric Leuthardt, Guy Genin, Matthew Smyth, David Limbrick, Daniel Moran, Lihong Wang, Aaron McLaughlin, Manish Shah, Alexander Yang, Samuel Stone, Devon Haydon, Michael Winek, Richard Marcus
  • Publication number: 20200288110
    Abstract: Systems and methods for stereo-polarimetric compressed-sensing ultrafast imaging.
    Type: Application
    Filed: March 5, 2020
    Publication date: September 10, 2020
    Inventors: Lihong Wang, Peng Wang, Jinyang Liang, Liren Zhu
  • Publication number: 20200275846
    Abstract: Among the various aspects of the present disclosure is the provision of systems and methods of velocity-matched ultrasonic tagging in photoacoustic flowgraphy.
    Type: Application
    Filed: March 2, 2020
    Publication date: September 3, 2020
    Inventors: Lihong Wang, Xiaoming Wei
  • Publication number: 20200268253
    Abstract: Among the various aspects of the present disclosure is the provision of systems and methods of imaging using photoacoustic computed tomography.
    Type: Application
    Filed: February 21, 2020
    Publication date: August 27, 2020
    Inventors: Lihong Wang, Peng Hu, Li Lin
  • Publication number: 20200253481
    Abstract: A photoacoustic medical-imaging device includes a wavelength conversion assembly (108) configured for outputting laser pulses at a targeted wavelength. It also includes a photoacoustic probe configured for acoustic coupling to a patient, for directing the pulses, and for acquiring, in response, radiofrequency data for photoacoustic imaging. It may include an optical fiber bundle (120) that comprises an optical fiber having an input end, and be configured for illuminating, with a homogenous beam, so as to conform to an acceptance angle (160) of the fiber at that end. It may also include a light collimator, and a diffuser for receiving the outputted laser pulses from the collimator. The diffuser may be configured for spreading a focus of the pulsed light (148) over an input aperture of the bundle to equalize the light received by different constituent optical fibers of the bundle. The assembly may include a dye cell (132), and may reside in the device.
    Type: Application
    Filed: May 1, 2020
    Publication date: August 13, 2020
    Inventors: KONSTANTIN MASLOV, TODD NICHOLAS ERPELDING, LADISLAV JANKOVIC, LIHONG WANG
  • Publication number: 20200220315
    Abstract: A photonic molecule laser is described that includes a photonic molecule waveguide coupled to a photonic molecule seeding source configured to deliver a plurality of photonic molecules. The photonic molecule waveguide includes a second dopant maintained at a population inverted state with an energy level transition corresponding to a second frequency that is an N-fold multiple of a first frequency and amplifies the number of photonic molecules via stimulated emission. The photonic molecule seeding source includes a waveguide with a first dopant maintained at a population inverted state with an energy level transition corresponding to the first frequency. A pump source is coupled to the waveguide configured to deliver a first frequency laser pulse with pulse coherence time less than the photonic molecules correlation time. Each photonic molecule includes a threshold bound state of N first frequency photons, and each photonic molecule has the second frequency.
    Type: Application
    Filed: October 12, 2018
    Publication date: July 9, 2020
    Applicant: WASHINGTON UNIVERSITY
    Inventors: Jung-Tsung Shen, Lihong Wang
  • Patent number: 10653321
    Abstract: Systems and methods for improving limited-view photoacoustic tomography using an acoustic reflector are described. In particular, an acoustic reflector and ultrasonic transducer array are integrated to provide a virtual array that enhances the field of view of the ultrasonic transducer array, thereby improving the quality of photoacoustic tomography images obtained using the systems and methods described herein.
    Type: Grant
    Filed: November 12, 2014
    Date of Patent: May 19, 2020
    Assignee: Washington University
    Inventors: Lihong Wang, Bin Huang, Jun Xia, Konstantin Maslov, Mark Anastasio
  • Patent number: 10625068
    Abstract: A breakaway connector generally includes a first valve having a first rotating-type fluid control member, and a second valve that is attachable to the first valve and has a second rotating-type fluid control member. Each of the fluid control members has an open position in which fluid is permitted to flow through the respective valve, and a closed position in which fluid is prevented from flowing through the respective valve. Each one of the valves is configured to engage the fluid control member of the other one of the valves to move the fluid control member from the open position to the closed position upon detachment of the valves from one another.
    Type: Grant
    Filed: February 23, 2016
    Date of Patent: April 21, 2020
    Assignee: Washington University
    Inventors: Eric Leuthardt, Guy Genin, Eric Arias, James Norlin, Brittany Scheid, Chandu Vemuri, Ralph Dacey, Colin Derdeyn, Gregory Zipfel, Albert Kim, Philip Bayly, Srikanth Singamaneni, Lihong Wang
  • Publication number: 20200115272
    Abstract: The present invention relates to the field of glass manufacturing, and discloses aluminoborosilicate glass, and a preparation method and an application thereof. Based on the total weight of components in the composition of the glass, the glass comprises: 33-60 wt % SiO2, 3-10 wt % Al2O3, 10-30 wt % B2O3, 1-15 wt % ZnO+TiO2+Sc2O3, and 7-27 wt % alkali-earth oxide RO, wherein RO is at least one of MgO, CaO, SrO and BaO, and 0.001 wt %?Sc2O3?1 wt %. The aluminoborosilicate glass provided in the present invention has advantages including low density, high index of refraction, low thermal expansion coefficient, high thermostability, high flexibility, and easy bending, etc.
    Type: Application
    Filed: April 16, 2018
    Publication date: April 16, 2020
    Applicants: TUNGHSU TECHNOLOGY GROUP CO., LTD., TUNGHSU GROUP CO., LTD.
    Inventors: Qing Li, Guangtao Zhang, Junfeng Wang, Xingjun Xu, Dongcheng Yan, Lihong Wang, Quan Zheng
  • Publication number: 20200073103
    Abstract: Apparatus and methods for measuring infrared absorption of a sample that includes delivering a pulse of infrared radiation to a region of the sample, delivering pulses of radiation of a shorter wavelength than infrared radiation to a sub-region within the region, and using one or more properties of the induced photoacoustic signals to create a signal indicative of infrared absorption of the sub-region of the sample.
    Type: Application
    Filed: September 4, 2019
    Publication date: March 5, 2020
    Inventors: Lihong Wang, Junhui Shi, Konstantin Maslov
  • Publication number: 20200055765
    Abstract: Provided are a device for press-cutting glass, a method for press-cutting glass, and a glass-cutting system having the device for press-cutting glass. The device for press-cutting glass comprises a supporting member, having a first supporting portion and a second supporting portion for supporting a glass substrate, which are arranged in a spaced apart manner in a first direction; and a press-cutting member for press-cutting an edge of the glass substrate, which is positioned between the first supporting portion and the second supporting portion in the first direction. The device for press-cutting glass has advantages including high press-cutting efficiency, simple structure, low manufacturing cost, and easy assembling with other devices.
    Type: Application
    Filed: May 4, 2018
    Publication date: February 20, 2020
    Applicants: TUNGHSU TECHNOLOGY GROUP CO., LTD., TUNGHSU GROUP CO., LTD.
    Inventors: Bo Zhou, Li Qing, Lihong Wang
  • Publication number: 20200056986
    Abstract: Multifocal photoacoustic imaging systems and methods that implement an ergodic relay to encode photoacoustic signals detected from a plurality of illuminated optical foci regions.
    Type: Application
    Filed: August 14, 2019
    Publication date: February 20, 2020
    Applicant: California Institute of Technology
    Inventors: Lihong Wang, Yang Li, Tsz Wai Wong