Patents by Inventor Lihong YUN

Lihong YUN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMBINATION OF ANTI-HER2 ANTIBODY AND CDK INHIBITIOR FOR TUMOR TREATMENT
    Publication number: 20230118053
    Abstract: The present application provides a medicinal product comprising: an the HER2 inhibitor or a CDK inhibitor, wherein said CDK inhibitor inhibits CDK4 and/or CDK6. The present application also provides an the HER2 inhibitor for the use of treating tumor in combination with a CDK inhibitor, as well as their use in the preparation of a medicament for treating tumor. The combination in present will significantly enhance tumor inhibiting.
    Type: Application
    Filed: March 26, 2021
    Publication date: April 20, 2023
    Inventors: Ting XU, Junfang XU, Pilin WANG, Jing YANG, Jiazhu FANG, Lihong YUN, Yanrong DONG
  • TROPHIC HORMONE FUSION PROTEIN, PREPARATION METHOD AND APPLICATION THEREOF
    Publication number: 20190055295
    Abstract: Disclosed herein is a gonadotropin fusion protein or a thyroid stimulating hormone fusion protein, a method for preparing the same and use thereof. ?-subunit of the gonadotropin or thyroid stimulating hormone is fused to an Fc fragment directly or indirectly through a linker, and ?-subunit binds to the ?-subunit via an affinity between the ?-subunit and the ?-subunit. The fusion protein has a prolonged half-life and less fluctuating activity.
    Type: Application
    Filed: May 14, 2018
    Publication date: February 21, 2019
    Inventors: Ting XU, Kangping GUO, Lihong YUN
  • Trophic hormone fusion protein, preparation method and application thereof
    Patent number: 9969786
    Abstract: Disclosed herein is a gonadotropin fusion protein or a thyroid stimulating hormone fusion protein, a method for preparing the same and use thereof. ?-subunit of the gonadotropin or thyroid stimulating hormone is fused to an Fc fragment directly or indirectly through a linker, and ?-subunit binds to the ?-subunit via an affinity between the ?-subunit and the ?-subunit. The fusion protein has a prolonged half-life and less fluctuating activity.
    Type: Grant
    Filed: November 22, 2013
    Date of Patent: May 15, 2018
    Assignee: Suzhou Alphamab Co, Ltd.
    Inventors: Ting Xu, Kangping Guo, Lihong Yun
  • TROPHIC HORMONE FUSION PROTEIN, PREPARATION METHOD AND APPLICATION THEREOF
    Publication number: 20160060321
    Abstract: Disclosed herein is a gonadotropin fusion protein or a thyroid stimulating hormone fusion protein, a method for preparing the same and use thereof. ?-subunit of the gonadotropin or thyroid stimulating hormone is fused to an Fc fragment directly or indirectly through a linker, and ?-subunit binds to the ?-subunit via an affinity between the ?-subunit and the ?-subunit. The fusion protein has a prolonged half-life and less fluctuating activity.
    Type: Application
    Filed: November 22, 2013
    Publication date: March 3, 2016
    Inventors: Ting XU, Kangping GUO, Lihong YUN