Abstract: This invention pertains to screening methods for identifying autophagy inducing compounds.

Abstract: While a heat-assisted, magnetic recording medium is being read from, power is applied to a write coil of a read/write head to control a spacing between a read transducer and the recording medium via thermal expansion induced by a write pole magnetically coupled to the write coil. A coefficient of thermal expansion proximate the read transducer is higher than a coefficient of thermal expansion proximate the write pole to increase a deformation at the read transducer relative to the write pole. Optionally, a media-facing surface of the read/write head may include a recess encompassing at least the write pole to prevent contact between the write pole and the recording medium while controlling the spacing.

Abstract: A data storage device may be configured with at least a transducing head separated from a data storage medium. The transducing head can have a data reader and data writer. A plurality of data bits may be arranged in first and second shingled data tracks on the data storage medium. The data writer can be configured with a writer centerline aligned with a track centerline of the first shingled data track and a data reader having a reader centerline skewed with respect to the track and writer centerlines.

Abstract: The present application provides a transducer head comprising a laser source configured to heat a target storage medium surface, and a thermal sensor configured to detect a defect on the target storage medium surface. The present application also provides a method comprising heating a target storage medium surface with an energy source configured in a transducer head to irradiate the target storage medium surface, and detecting a defect on the target storage medium surface using a thermal sensor configured in the transducer head. Other implementations are also described and recited herein.

Abstract: A data storage device may be configured with at least a transducing head separated from a data storage medium. The transducing head can have a data reader and data writer. A plurality of data bits may be arranged in first and second shingled data tracks on the data storage medium. The data writer can be configured with a writer centerline aligned with a track centerline of the first shingled data track and a data reader having a reader centerline skewed with respect to the track and writer centerlines.

Abstract: An apparatus that includes a storage layer and a heating assistance element. The heating assistance element is adjacent to the storage layer or doped into the storage layer. The heating assistance element is configured to enhance spatial confinement of energy from a field to an area of the storage layer to which the field is applied.

Abstract: The present disclosure relates to a piezoelectric charging system, which has two operational modes: a vibration mode and a charging mode. The system includes a piezoelectric vibrator, a driving module, a switch selecting module, a rectifying and processing module and a charging control module. The present disclosure can make full use of the mechanical energy from human beings and the ambient environment to provide the electronic device with an important energy source. Furthermore, energy can be charged to the electronic devices in real time. Furthermore, the present disclosure provides a terminal device using the piezoelectric charging system.

Abstract: Provided is an apparatus including a motor configured to rotate a rotating member at a rotational speed based on an applied current; and a controller configured to modify one or more operating parameters in response to determining whether a change in an environment has occurred based on the applied current.

Abstract: Provided is an apparatus including a motor configured to rotate a rotating member at a rotational speed based on an applied current; and a controller configured to modify one or more operating parameters in response to determining whether a change in an environment has occurred based on the applied current.

Abstract: A slider generally comprises a substrate forming at least part of a body of the slider, a heat-assisted media recording (HAMR) read/write transducer proximate the substrate, and an end cap substantially encapsulating the HAMR read/write transducer. The end cap has a first surface proximate the substrate and a second surface as a trailing edge of the slider. The end cap has a first coefficient of thermal expansion (CTE) similar to a corresponding CTE of the substrate. At least a portion of the second surface of the end cap has a second CTE that is lower than the first CTE. A body of the end cap is intermediate to the first and second surfaces of the end cap and has a CTE intermediate of the first and second CTE.

Abstract: A device may be configured at least with a controller connected to a transducer or transducing assembly that is positioned proximal a data storage medium having at least one thermal asperity or other similar defect. The controller may be configured to select a clearance height above the data storage medium in response to a measured severity of the at least one thermal asperity.

Abstract: A screen sounder includes a housing having a front case, a screen supported by the front case, a piezoelectric module mounted with the screen for driving the screen to generate sound or converting vibration of the screen into electric energy, an audio signal source electrically connecting to the piezoelectric module for driving the piezoelectric module to vibrate, a rechargeable module electrically connecting to the piezoelectric module for receiving the electric energy, and a switching control unit electrically connecting with the piezoelectric module for switching the electrical connections between the audio signal source, the rechargeable module and the piezoelectric module.

Abstract: An apparatus that includes a storage layer and a heating assistance element. The heating assistance element is adjacent to the storage layer or doped into the storage layer. The heating assistance element is configured to enhance spatial confinement of energy from a field to an area of the storage layer to which the field is applied.

Abstract: A screen sounder includes a housing having a front case, a screen supported by the front case, a piezoelectric module mounted with the screen for driving the screen to generate sound or converting vibration of the screen into electric energy, an audio signal source electrically connecting to the piezoelectric module for driving the piezoelectric module to vibrate, a rechargeable module electrically connecting to the piezoelectric module for receiving the electric energy, and a switching control unit electrically connecting with the piezoelectric module for switching the electrical connections between the audio signal source, the rechargeable module and the piezoelectric module.

Abstract: The present disclosure relates to a piezoelectric charging system, which has two operational modes: a vibration mode and a charging mode. The system includes a piezoelectric vibrator, a driving module, a switch selecting module, a rectifying and processing module and a charging control module. The present disclosure can make full use of the mechanical energy from human beings and the ambient environment to provide the electronic device with an important energy source. Furthermore, energy can be charged to the electronic devices in real time. Furthermore, the present disclosure provides a terminal device using the piezoelectric charging system.

Abstract: Apparatus for recording data and method for making the same. In accordance with some embodiments, a magnetic recording layer is adapted to store data along perpendicular magnetic domains. A protective overcoat layer is formed on the magnetic recording layer to substantially protect the magnetic recording layer from environmental effects. The protective overcoat layer is made of carbon intermixed with at least one transition metal, such as but not limited to chromium.

Abstract: Certain aspects of the invention relates to small molecule autophagy inhibitors of the formula (I), and their use for treatment and prevention of cancers and acute pancreatitis. As disclosed herein, a small molecule inhibitor of autophagy was been identified from an image-based screen in a known bioactive library. It was found that this autophagy inhibitor functions by promoting the degradation of type III PI3 kinase complex which is required for initiating autophagy. Medicinal chemistry studies led to small molecular autophagy inhibitors with improved potency and selectivity.

Abstract: The present invention provides a method for increasing storage capacity of a disc drive by physically skewing a transducer in relation to a slider supporting the transducer. The physical skew angle of the transducer is configured to provide a predetermined zero skew position on the medium, which is capable of providing an increased storage capacity to the medium. To ascertain this zero skew position, a storage density or storage capacity of the medium may be ascertained for each of various zero skew positions on the medium. A desired storage density or capacity level is selected according to storage capacity requirements and the corresponding zero skew position is ascertained. The corresponding zero skew position may be implemented by physically skewing a transducer relative to a slider.

Abstract: This invention pertains to a class of autophagy inducing compounds that treat diseases caused by misfolded protein aggregates and a screening method for identifying these compounds.

Abstract: An integrated filter assembly is provided. The filter assembly includes a fastener that holds two substantially opposing elements of a housing together. Also included is a multi-purpose filter that has at least a particle filter component and a chemical filter component. The multi-purpose filter is attached to the fastener. The multi-purpose filter is within the housing when the fastener holds the two substantially opposing elements of the housing together.