Abstract: The invention relates to a garment care device (D) comprising a chamber (C) to receive at least one garment (G). The garment care device (D) also comprises a heating system (HS) for heating the at least one garment (G). The garment care device (D) also comprises a lighting system (LS) for emitting inside the chamber (C), a radiation having wavelength in the range [280; 500] nm. The garment care device (D) also comprises a metal oxide photocatalyst element (MO) disposed inside the chamber (C) such that the metal oxide photocatalyst element (MO) can receive the radiation. The chamber (C) comprises receiving means to receive the at least one garment (G) such that the at least one garment (G) remains spaced from the metal oxide photocatalyst element (MO). The garment care device according to the invention allows the combination of drying and sanitizing of garments, while imparting pleasant smell to garment in a safe and eco-friendly way.

Abstract: Single-stranded RNA molecules comprise one or more internal, non-nucleotide spacers, covalently linked with nucleotide portions of the molecule are provided. The single-stranded RNA molecules function as guide or antisense strands that are capable of inhibiting gene expression via an RNA interference mechanism, and thus represent single-stranded RNAi agents. The single-stranded RNAi molecules can be used in methods for a variety of therapeutic, diagnostic, target validation, genomic discovery, genetic engineering, and pharmacogenomic applications.

Abstract: The present application relates to steam iron (1). The steam iron (1) comprises a sole plate (3). The sole plate (3) has a steam channel (6) for the passage of steam, an ironing surface (10), vents (4) for the passage of steam between the steam channel (6) and the ironing surface (10), an aperture (9) extending between the steam channel (6) and the ironing surface (10), and a fragrance cartridge (7) being received in the aperture (9) such that it extends into the steam channel (6) to diffuse fragrance in the steam channel (6). The aperture (9) secures the fragrance cartridge (10) in the sole plate (3) such that fragrance cartridge (7) is flush with the ironing surface (10). The present invention also relates to a fragrance cartridge (7) and to a method of imparting a fragrance to steam produced by a steam iron (1).

Abstract: Disclosed are a composite material, a shell for a mobile device, their manufacturing methods, and a mobile device. The composite material includes: a first metal substrate (100); a first resin fibre plate (200) disposed on an upper surface of the first metal substrate; an antenna layer (300) disposed on an upper surface of the first resin fibre plate; a second resin fibre plate (400) disposed on an upper surface of the antenna layer; and a second metal substrate (500) disposed on an upper surface of the second resin fibre plate.

Abstract: The invention relates to a treatment plate (10) for a garment treatment appliance (100) for treating garments (30), which plate has a contact surface which is provided with a sol-gel coating (20) that comprises an oxide of titanium, zirconium, hafnium, scandium, yttrium, or a mixture or combination thereof. The layer preferably has a thickness of less than 1 ?m. Such a layer shows excellent properties. A garment treatment appliance comprising such a treatment plate, as well as processes to produce the coating on the contact surface of the treatment plate are also disclosed.

Abstract: This invention relates generally to segmented oligonucleotides capable of modulating gene expression. Specifically, the instant invention relates to segmented microRNA (miRNA) oligonucleotides, including segmented miRNA precursors and segmented pre-microRNAs. The invention also relates to compositions comprising such segmented oligonucleotides, as well as to methods of making and using such oligonucleotides for diagnosis and treatment of diseases associated or causally linked to aberrant levels or activities of gene expression, including aberrant levels of coding and/or non-coding RNA.

Abstract: A metal-plastic composite and method for producing the same are provided. The metal-plastic composite comprises: a metal substrate and a plastic body jointed to the metal substrate via a dual-snap-fit structure, in which the dual-snap-fit structure comprises: a micro-snap-fit structure disposed on the metal substrate and a macro-snap-fit structure formed by the micro-snap-fit structure and a surface of the metal substrate.

Abstract: Single-stranded RNA molecules comprise one or more internal, non-nucleotide spacers, covalently linked with nucleotide portions of the molecule are provided. The single-stranded RNA molecules function as guide or antisense strands that are capable of inhibiting gene expression via an RNA interference mechanism, and thus represent single-stranded RNAi agents. The single-stranded RNAi molecules can be used in methods for a variety of therapeutic, diagnostic, target validation, genomic discovery, genetic engineering, and pharmacogenomic applications.

Abstract: Single-stranded RNA molecules comprise one or more internal, non-nucleotide spacers, covalently linked with nucleotide portions of the molecule are provided. The single-stranded RNA molecules function as guide or antisense strands that are capable of inhibiting gene expression via an RNA interference mechanism, and thus represent single-stranded RNAi agents. The single-stranded RNAi molecules can be used in methods for a variety of therapeutic, diagnostic, target validation, genomic discovery, genetic engineering, and pharmacogenomic applications.

Abstract: The invention relates to a treatment plate (10) for a garment treatment appliance (100) for treating garments (30), which plate has a contact surface which is provided with a sol-gel coating (20) that comprises an oxide of titanium, zirconium, hafnium, scandium, yttrium, or a mixture or combination thereof. The layer preferably has a thickness of less than 1 ?m. Such a layer shows excellent properties. A garment treatment appliance comprising such a treatment plate, as well as processes to produce the coating on the contact surface of the treatment plate are also disclosed.

Abstract: This invention relates generally to segmented oligonucleotides capable of modulating gene expression. Specifically, the instant invention relates to segmented microRNA (miRNA) oligonucleotides, including segmented miRNA precursors and segmented pre-microRNAs. The invention also relates to compositions comprising such segmented oligonucleotides, as well as to methods of making and using such oligonucleotides for diagnosis and treatment of diseases associated or causally linked to aberrant levels or activities of gene expression, including aberrant levels of coding and/or non-coding RNA.

Abstract: This invention relates generally to segmented oligonucleotides capable of modulating gene expression. Specifically, the instant invention relates to segmented microRNA (miRNA) oligonucleotides, including segmented miRNA precursors and segmented pre-microRNAs. The invention also relates to compositions comprising such segmented oligonucleotides, as well as to methods of making and using such oligonucleotides for diagnosis and treatment of diseases associated or causally linked to aberrant levels or activities of gene expression, including aberrant levels of coding and/or non-coding RNA.

Abstract: This invention relates generally to segmented oligonucleotides capable of modulating gene expression. Specifically, the instant invention relates to segmented microRNA (miRNA) oligonucleotides, including segmented miRNA precursors and segmented pre-microRNAs. The invention also relates to compositions comprising such segmented oligonucleotides, as well as to methods of making and using such oligonucleotides for diagnosis and treatment of diseases associated or causally linked to aberrant levels or activities of gene expression, including aberrant levels of coding and/or non-coding RNA.

Abstract: Single-stranded RNA molecules comprise one or more internal, non-nucleotide spacers, covalently linked with nucleotide portions of the molecule are provided. The single-stranded RNA molecules function as guide or antisense strands that are capable of inhibiting gene expression via an RNA interference mechanism, and thus represent single-stranded RNAi agents. The single-stranded RNAi molecules can be used in methods for a variety of therapeutic, diagnostic, target validation, genomic discovery, genetic engineering, and pharmacogenomic applications.

Abstract: A key-press structure comprises a transparent substrate, a plurality of characters formed inside the transparent substrate thereby forming a plurality of keys, and a touch control member disposed on the surface of the transparent substrate such that each of the keys is operable to sense a touch event.

Abstract: A key-press structure comprises a transparent substrate, a plurality of characters formed inside the transparent substrate thereby forming a plurality of keys, and a touch control member disposed on the surface of the transparent substrate such that each of the keys is operable to sense a touch event.

Abstract: In one aspect, a key-press structure comprises a frame and a plurality of keys disposed in said frame. Said frame comprises a main portion and two reflecting portions. The main portion has two opposite sides and the two reflecting portions are disposed on the two opposite sides of the main portion, respectively. Said reflecting portion has a reflective surface facing toward the main portion. Said keys are made of a transparent material, and the keys comprise characters formed on the internal surface of said keys. In another aspect, a method of preparing a key-press structure comprises forming a frame that includes a main portion and two reflecting portions. The reflecting portions each have a reflective surface. The main portion has two opposite sides that is connected to the two reflecting portions. The method further comprises forming characters on the internal surface of a plurality of keys, and disposing said keys in the main portion of the frame.

Abstract: In one aspect, a key-press structure comprises a frame and a plurality of keys disposed in said frame. Said frame comprises a main portion and two reflecting portions. The main portion has two opposite sides and the two reflecting portions are disposed on the two opposite sides of the main portion, respectively. Said reflecting portion has a reflective surface facing toward the main portion. Said keys are made of a transparent material, and the keys comprise characters formed on the internal surface of said keys. In another aspect, a method of preparing a key-press structure comprises forming a frame that includes a main portion and two reflecting portions. The reflecting portions each have a reflective surface. The main portion has two opposite sides that is connected to the two reflecting portions. The method further comprises forming characters on the internal surface of a plurality of keys, and disposing said keys in the main portion of the frame.

Abstract: A coated plastic sheet comprises a transparent plastic sheet having a top and bottom surface, and a first film on the top surface and covering less than all of the top surface, thereby creating at least one uncovered area. At least a portion of the first film has a first metallic luster on its exposed surface. The coated plastic sheet also comprises a second film on the bottom surface. At least a portion of the second film is visible through the uncovered area of the sheet, wherein the second film presents a second metallic luster through the uncovered area.

Abstract: The present invention provides compositions and methods for preparation of a three-dimensional transendothelial cell migration (TEM) assay. These compositions and methods are uniquely suited for the high throughput TEM assay, and for the analysis and identification of TEM mediators which inhibit or stimulate this process. The composition for detecting migration of cells comprises a solid layer comprising collagen gel; a first cellular layer in contact with the solid layer and comprising a first cell type; and a second cell type seeded on top of the first cellular layer. Optionally, gelatin is included in the collagen gel. A 96 well plate format is disclosed, the combination with a high throughput cellular scanner enables high throughput TEM assay.