Patents by Inventor Lihua Yao

Lihua Yao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240389474
    Abstract: A low-cost and high-strength Bi-based superconducting wire/tape and a preparation method thereof, the preparation method includes: 1. subjecting a first Bi-based superconducting wire/tape to electrochemical silver reduction to remove a Ag alloy layer to obtain a second Bi-based superconducting wire/tape; and 2. subjecting the second Bi-based superconducting wire/tape to surface enhancement, such that a Cu layer is formed to obtain the low-cost and high-strength Bi-based superconducting wire/tape. An electrochemical silver reduction technology combines with an electrochemical additive method to remove a Ag alloy layer on a surface of a Bi-based superconducting wire/tape and coat a high-strength Cu layer, such that a low-cost and high-strength Bi-based superconducting wire/tape can be prepared, which reduces a preparation cost and improves a strength of a Bi-based superconducting wire/tape to meet the application requirements of large super-strong magnets.
    Type: Application
    Filed: May 3, 2024
    Publication date: November 21, 2024
    Applicant: NORTHWEST INSTITUTE FOR NONFERROUS METAL RESEARCH
    Inventors: Qingbin HAO, Jianfeng LI, Shengnan ZHANG, Lihua JIN, Xiaoyan XU, Gaofeng JIAO, Kai YAO, Chengshan LI, Guoqing LIU, Zhenbao LI, Xueqian LIU, Gaoshan LI, Jianqing FENG, Pingxiang ZHANG
  • Publication number: 20170081701
    Abstract: A device and method for determining the presence or absence, or the level of, sPLA2 activity in a fluid sample. The device includes an absorbent matrix that defines a flow path for a fluid sample, a first region of the absorbent matrix for applying a fluid sample, where one of the components selected from a bioactive sPLA2 substrate and a label is dried onto or within the first region of the absorbent matrix, a second region of the absorbent matrix downstream of, and in fluid communication with, the first region for detecting an aggregated reaction product, where the other component not present in the first region is dried onto or within the second region of the absorbent matrix.
    Type: Application
    Filed: December 1, 2016
    Publication date: March 23, 2017
    Applicant: Drexel University
    Inventors: Timothy J. Cunningham, Katherine Marie Kollins Callaghan, Lihua Yao
  • Publication number: 20150079607
    Abstract: The present invention relates to methods useful to monitor central and peripheral nervous system neuron/axon destruction resulting from an increase in acute phase inflammatory enzymes. The methods have applicability to monitoring the progress of neurological diseases, including multiple sclerosis and Alzheimer's disease, as well as neuroinflammatory damage that results from sports injuries, vigorous physical activity or any form of physical abuse. The invention further relates to methods of treating multiple sclerosis or other diseases with an inflammatory component related to phospholipase A2.
    Type: Application
    Filed: June 5, 2014
    Publication date: March 19, 2015
    Applicant: Philadelphia Health and Education Corporation, d/b/a Drexel University College of Medicine
    Inventors: Timothy J. Cunningham, Lihua Yao
  • Publication number: 20150044714
    Abstract: A device and method for determining the presence or absence, or the level of, sPLA2 activity in a fluid sample. The device includes an absorbent matrix that defines a flow path for a fluid sample, a first region of the absorbent matrix for applying a fluid sample, where one of the components selected from a bioactive sPLA2 substrate and a label is dried onto or within the first region of the absorbent matrix, a second region of the absorbent matrix downstream of, and in fluid communication with, the first region for detecting an aggregated reaction product, where the other component not present in the first region is dried onto or within the second region of the absorbent matrix.
    Type: Application
    Filed: June 5, 2012
    Publication date: February 12, 2015
    Applicant: Philadelphia Health & Education Corporation d/b/a Drexel University College of Medicine
    Inventors: Timothy J. Cunningham, Katherine Marie Kollins Callaghan, Lihua Yao
  • Publication number: 20140213526
    Abstract: A synthetic peptide sequence demonstrating neuroprotective and anti-inflammatory functions is disclosed. Methods of use for the synthetic peptide are also provided.
    Type: Application
    Filed: March 27, 2014
    Publication date: July 31, 2014
    Applicant: Drexel University
    Inventors: Timothy J. Cunningham, Lihua Yao
  • Patent number: 8785401
    Abstract: The present invention relates to methods useful to monitor central and peripheral nervous system neuron/axon destruction resulting from an increase in acute phase inflammatory enzymes. The methods have applicability to monitoring the progress of neurological diseases, including multiple sclerosis and Alzheimer's disease, as well as neuroinflammatory damage that results from sports injuries, vigorous physical activity or any form of physical abuse. The invention further relates to methods of treating multiple sclerosis or other diseases with an inflammatory component related to phospholipase A2.
    Type: Grant
    Filed: July 10, 2006
    Date of Patent: July 22, 2014
    Assignee: Philadelphia Health & Education Corporation
    Inventors: Timothy J. Cunningham, Lihua Yao
  • Patent number: 8716223
    Abstract: A synthetic peptide sequence demonstrating neuroprotective and anti-inflammatory functions is disclosed. Methods of use for the synthetic peptide are also provided.
    Type: Grant
    Filed: May 5, 2009
    Date of Patent: May 6, 2014
    Assignee: Drexel University
    Inventors: Timothy J. Cunningham, Lihua Yao
  • Patent number: 8106019
    Abstract: The present invention relates to the discovery of a composition including a seven-amino acid peptide that promotes neuronal survival, inhibits inflammation, and is a potent inhibitor of sPL2A, and uses thereof.
    Type: Grant
    Filed: October 12, 2007
    Date of Patent: January 31, 2012
    Assignee: Philadelphia Health & Education Corporation
    Inventors: Timothy J. Cunningham, Lihua Yao, Jeffrey I. Greenstein
  • Publication number: 20090286746
    Abstract: A synthetic peptide sequence demonstrating neuroprotective and anti-inflammatory functions is disclosed. Methods of use for the synthetic peptide are also provided.
    Type: Application
    Filed: May 5, 2009
    Publication date: November 19, 2009
    Inventors: Timothy J. Cunningham, Lihua Yao
  • Publication number: 20090181879
    Abstract: The present invention relates to methods useful to monitor central and peripheral nervous system neuron/axon destruction resulting from an increase in acute phase inflammatory enzymes. The methods have applicability to monitoring the progress of neurological diseases, including multiple sclerosis and Alzheimer's disease, as well as neuroinflammatory damage that results from sports injuries, vigorous physical activity or any form of physical abuse. The invention further relates to methods of treating multiple sclerosis or other diseases with an inflammatory component related to phospholipase A2.
    Type: Application
    Filed: July 10, 2006
    Publication date: July 16, 2009
    Applicant: Philadelphia Health & Education Corporation d/b/a Drexel University College of Medicine
    Inventors: Timothy J. Cunningham, Lihua Yao, Jeffrey I. Greenstein
  • Patent number: 7528112
    Abstract: A synthetic peptide sequence demonstrating neuroprotective and anti-inflammatory functions is disclosed. Methods of use for the synthetic peptide are also provided.
    Type: Grant
    Filed: November 17, 2003
    Date of Patent: May 5, 2009
    Assignee: Drexel University
    Inventors: Timothy J. Cunningham, Lihua Yao
  • Publication number: 20080249027
    Abstract: The present invention relates to the discovery of a composition including a seven-amino acid peptide that promotes neuronal survival, inhibits inflammation, and is a potent inhibitor of sPL2A, and uses thereof.
    Type: Application
    Filed: October 12, 2007
    Publication date: October 9, 2008
    Inventors: Timothy J. Cunningham, Lihua Yao, Jeffrey I. Greenstein
  • Publication number: 20040132665
    Abstract: A synthetic peptide sequence demonstrating neuroprotective and anti-inflammatory functions is disclosed. Methods of use for the synthetic peptide are also provided.
    Type: Application
    Filed: November 17, 2003
    Publication date: July 8, 2004
    Inventors: Timothy J. Cunningham, Lihua Yao