Patents by Inventor Lihui Zhao
Lihui Zhao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250018447Abstract: A lifting control apparatus may include: a base for holding a basket containing silicon wafers; brackets provided on an outside of both ends of the base; and a driver for driving the brackets to move up and down. The driver is provided with a lead screw. The lead screw is connected with the bracket on a same side. The lead screw on one side is driven to rotate the lead screw on another side synchronously, and the lead screws on both sides are driven to move the brackets on both sides and the base between the brackets up and down together. Or the lead screws on both sides are driven to rotate synchronously, so that the lead screws on both sides drive the base between the brackets through the correspondingly brackets to move up and down together.Type: ApplicationFiled: July 31, 2023Publication date: January 16, 2025Applicant: TCL ZHONGHUAN RENEWABLE ENERGY TECHNOLOGY CO., LTD.Inventors: Lihui JIN, Hua YANG, Zhigao REN, Xiaoguang ZHAO, Hao GUO, Chuanling AI, Dawei WANG, Zhijun WU, Hongxia CEN, Chen WEI
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Patent number: 12017714Abstract: An active-passive differential series-parallel connection supporting leg, a gravity-based closing series-parallel connection supporting leg, and a six-degree-of-freedom position-adjusting robot platform are provided. The six-degree-of-freedom position-adjusting robot platform is formed of a plurality of legs distributed in parallel, and includes a frame, a distributed controller, and multi-chain parallel legs, wherein a plurality of legs are fixedly connected with the frame through a base. The present disclosure integrates an omnidirectional movement and position adjustment to solve problems that the existing position-adjusting platform is fixed or moved inflexibly, the structure is over complicated, the occupation space is excessive, and the movement error is large, and thereby effectively expanding application range of the six-degree-of-freedom position-adjusting robot platform.Type: GrantFiled: June 29, 2021Date of Patent: June 25, 2024Assignee: VANSHAN UNIVERSITYInventors: Yulin Zhou, Lihui Zhao, Hongpeng Chu, Yi Liu, Shuyang Shi
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Publication number: 20240191301Abstract: Described herein are methods, compositions, and systems useful for detecting transplant rejection and associated abnormal conditions in solid organ transplant recipients, such as kidney transplant recipients. Methods described herein may involve combined assessment of blood gene expression profiles from an assessment of particular, related mRNA transcript levels and donor-derived cell-free nucleic acids (dd-cfDNA).Type: ApplicationFiled: January 26, 2024Publication date: June 13, 2024Applicants: Northwestern University, Transplant Genomics, Inc., The Scripps Research InstituteInventors: John Friedewald, Michael M. Abecassis, Rohita Sinha, Sook Hyeon Park, Lihui Zhao, Juston Weems, Sunil M. Kurian, Steve Kleiboeker
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Patent number: 11995385Abstract: A matching design method of static stiffness for a combined box body structure of a large reducer is provided, including the following steps, building a transmission system model and an initial structure model and obtaining load data; performing a statics analysis; obtaining primary design variables and design responses; constructing design variables; constructing a static stiffness matching target of a combined box body; constructing an objective function; setting constraint conditions; constructing a response surface proxy model; constructing a static stiffness matching optimization model of combined box body; obtaining optimal design variables and obtaining an optimal structure model of the box body; performing the statics analysis on the optimal structure model of the box body, and performing a contrastive analysis with statics analysis results of the corrected box body two-dimensional unit finite element model to confirm optimization effects.Type: GrantFiled: January 16, 2024Date of Patent: May 28, 2024Assignee: University of Shanghai for Science and TechnologyInventors: Lihui Zhao, Dongdong Zhang, Shuo Weng, Jinzhi Feng, Kang Du, Zhen Wang
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Patent number: 11945271Abstract: A rigid-flexible coupling multi-degree-of-freedom walking position-adjusting leg unit and a hybrid robot platform thereof is provided and includes a vertical rigid-flexible coupling multi-degree-of-freedom walking position-adjusting leg unit and a horizontal rigid-flexible coupling multi-degree-of-freedom walking position-adjusting leg unit, which both include a moving device, a moving drive, a steering frame, a lifting frame, a spring device and a driving differential wheel set, in combination with a frame, a driver set, a battery pack and a control box, forming a multi-degree-of-freedom parallel mechanism platform. The hybrid robot platform including the rigid-flexible coupling multi-degree-of-freedom walking position-adjusting leg unit as provided by the present disclosure has functions of a rigid position adjustment, an elastic suspension and a rigid-flexible coupling position adjustment, and can automatically adapt to a working condition of the uneven ground.Type: GrantFiled: August 24, 2021Date of Patent: April 2, 2024Assignee: YANSHAN UNIVERSITYInventors: Yulin Zhou, Shuyang Shi, Lihui Zhao, Xuesong Qiu, Zongqiang Feng, Yi Liu
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Patent number: 11835419Abstract: The present invention discloses a method for the rapid assessment of the service life of a hub bearing under multiaxial random road loading, comprising the following steps: acquiring a measured load spectrum of a wheel center of an automobile, and converting the wheel center load into an axial load and a radial load borne by a hub unit; performing load level division on the axial load and radial load borne by the hub unit, and performing joint distribution counting; according to the deformation coordination relationship between a roller and a raceway of the bearing, establishing a bearing contact model under a joint load, and according to the bearing contact model and the result of joint distribution counting, calculating the actual contact load of the bearing under different loads; and calculating the equivalent dynamic load and the life of the bearing through the actual contact load of the bearing to obtain the total equivalent damage of the bearing.Type: GrantFiled: August 3, 2021Date of Patent: December 5, 2023Assignee: UNIVERSITY OF SHANGHAI FOR SCIENCE AND TECHNOLOGYInventors: Lihui Zhao, Qichen Li, Zhen Wang, Jinzhi Feng, Songlin Zheng, Dawei Gao, Shuo Weng
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Patent number: 11669652Abstract: Disclosed is a robust topology optimization design method of a damping composite stiffened cylindrical shell box structure, comprising: constructing working load data, and obtaining circumferential target modal frequencies based on the working load data and the stiffened cylindrical shell box; laying constrained layer damping materials on the stiffened cylindrical shell box to construct a damping composite stiffened cylindrical shell box; constructing interval parameters based on the damping composite stiffened cylindrical shell box, and obtaining modal loss factor based on the interval parameters; constructing an objective function based on the modal loss factors, constructing design variables and constraint conditions based on the damping composite stiffened cylindrical shell box, integrating the objective function, design variables and constraint conditions to form an interval robust topology optimization model; updating the design variables based on the interval robust topology optimization model, and obtType: GrantFiled: September 19, 2022Date of Patent: June 6, 2023Assignees: Harbin Marine Boiler and Turbine Research Institute, BEIJING INSTITUTE OF TECHNOLOGY, University of Shanghai for Science and TechnologyInventors: Shenggang Luan, Hongzhi Ji, Yanjiong Yue, Xunmin Yin, Dongdong Zhang, Lihui Zhao, Shouwen Yao, Yingchun Bai
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Publication number: 20230099953Abstract: Disclosed is a robust topology optimization design method of a damping composite stiffened cylindrical shell box structure, comprising: constructing working load data, and obtaining circumferential target modal frequencies based on the working load data and the stiffened cylindrical shell box; laying constrained layer damping materials on the stiffened cylindrical shell box to construct a damping composite stiffened cylindrical shell box; constructing interval parameters based on the damping composite stiffened cylindrical shell box, and obtaining modal loss factor based on the interval parameters; constructing an objective function based on the modal loss factors, constructing design variables and constraint conditions based on the damping composite stiffened cylindrical shell box, integrating the objective function, design variables and constraint conditions to form an interval robust topology optimization model; updating the design variables based on the interval robust topology optimization model, and obtType: ApplicationFiled: September 19, 2022Publication date: March 30, 2023Applicants: Harbin Marine Boiler and Turbine Research Institute, BEIJING INSTITUTE OF TECHNOLOGY, University of Shanghai for Science and TechnologyInventors: Shenggang LUAN, Hongzhi JI, Yanjiong YUE, Xunmin YIN, Dongdong ZHANG, Lihui ZHAO, Shouwen YAO, Yingchun BAI
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Patent number: 11591333Abstract: The present invention provides a method for preparing a pyrrolopyrimidine compound and application thereof. Specifically, the present invention provides a compound represented by formula I or pharmaceutically-acceptable salts thereof, a pharmaceutical composition containing the compound or its salts, and a method for preparing the pharmaceutical composition and an application of the pharmaceutical composition as an immunosuppressive drug.Type: GrantFiled: February 22, 2017Date of Patent: February 28, 2023Assignees: CINAKATE PHARM TECH (SHANGHAI) CO., LTD., CINKATE PHARMACEUTICAL INTERMEDIATES CO., LTD.Inventors: Na Liu, Lixia Bao, Zhepeng Wei, Yufeng Zhou, Bin Rong, Lihui Zhao, Fei Xiao
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Publication number: 20220381646Abstract: The present invention discloses a method for the rapid assessment of the service life of a hub bearing under multiaxial random road loading, comprising the following steps: acquiring a measured load spectrum of a wheel center of an automobile, and converting the wheel center load into an axial load and a radial load borne by a hub unit; performing load level division on the axial load and radial load borne by the hub unit, and performing joint distribution counting; according to the deformation coordination relationship between a roller and a raceway of the bearing, establishing a bearing contact model under a joint load, and according to the bearing contact model and the result of joint distribution counting, calculating the actual contact load of the bearing under different loads; and calculating the equivalent dynamic load and the life of the bearing through the actual contact load of the bearing to obtain the total equivalent damage of the bearing.Type: ApplicationFiled: August 3, 2021Publication date: December 1, 2022Applicant: UNIVERSITY OF SHANGHAI FOR SCIENCE AND TECHNOLOGYInventors: Lihui ZHAO, Qichen LI, Zhen WANG, Jinzhi FENG, Songlin ZHENG, Dawei GAO, Shuo WENG
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Compilation Method for Reliability Test Load Spectrum of High-Speed Bearing of Electric Drive System
Publication number: 20220364953Abstract: The present invention discloses a compilation method for a reliability test load spectrum of a high-speed bearing of an electric drive system. The method comprises the following steps: based on load data of a whole life cycle of an electric drive system, correlating a leading failure load of a high-speed bearing; counting an action frequency of each load level by a multi-dimensional load joint counting method; constructing a bearing mechanical balance equation; determining a reliability test load level by damage contribution distribution and cumulative damage contribution distribution of different load levels; according to a principle of a consistent overall frequency and consistent damage, determining a time of the reliability test load level; and in combination with extreme load working conditions, finally constructing a reliability test load spectrum of the high-speed bearing.Type: ApplicationFiled: August 3, 2021Publication date: November 17, 2022Applicant: UNIVERSITY OF SHANGHAI FOR SCIENCE AND TECHNOLOGYInventors: Lihui ZHAO, Zhen WANG, Qichen LI, Longjie LIU, Jinzhi FENG, Songlin ZHENG, Dawei GAO, Shuo WENG -
Publication number: 20220017522Abstract: The present invention provides a method for preparing a pyrrolopyrimidine compound and application thereof. Specifically, the present invention provides a compound represented by formula I or pharmaceutically-acceptable salts thereof, a pharmaceutical composition containing the compound or its salts, and a method for preparing the pharmaceutical composition and an application of the pharmaceutical composition as an immunosuppressive drug.Type: ApplicationFiled: February 22, 2017Publication date: January 20, 2022Inventors: Na LIU, Lixia BAO, Zhepeng WEI, Yufeng ZHOU, Bin RONG, Lihui ZHAO, Fei XIAO
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Publication number: 20210379952Abstract: A rigid-flexible coupling multi-degree-of-freedom walking position-adjusting leg unit and a hybrid robot platform thereof is provided and includes a vertical rigid-flexible coupling multi-degree-of-freedom walking position-adjusting leg unit and a horizontal rigid-flexible coupling multi-degree-of-freedom walking position-adjusting leg unit, which both include a moving device, a moving drive, a steering frame, a lifting frame, a spring device and an driving differential wheel set, in combination with a frame, a driver set, a battery pack and a control box, forming a multi-degree-of-freedom parallel mechanism platform. The hybrid robot platform including the rigid-flexible coupling multi-degree-of-freedom walking position-adjusting leg unit as provided by the present disclosure has functions of a rigid position adjustment, an elastic suspension and a rigid-flexible coupling position adjustment, and can automatically adapt to a working condition of the uneven ground.Type: ApplicationFiled: August 24, 2021Publication date: December 9, 2021Inventors: Yulin Zhou, Shuyang Shi, Lihui Zhao, Xuesong Qiu, Zongqiang Feng, Yi LIU
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Publication number: 20210323621Abstract: An active-passive differential series-parallel connection supporting leg, a gravity-based closing series-parallel connection supporting leg, and a six-degree-of-freedom position-adjusting robot platform are provided. The six-degree-of-freedom position-adjusting robot platform is formed of a plurality of legs distributed in parallel, and includes a frame, a distributed controller, and multi-chain parallel legs, wherein a plurality of legs are fixedly connected with the frame through a base. The present disclosure integrates an omnidirectional movement and position adjustment to solve problems that the existing position-adjusting platform is fixed or moved inflexibly, the structure is over complicated, the occupation space is excessive, and the movement error is large, and thereby effectively expanding application range of the six-degree-of-freedom position-adjusting robot platform.Type: ApplicationFiled: June 29, 2021Publication date: October 21, 2021Inventors: Yulin Zhou, Lihui Zhao, Hongpeng Chu, Yi Liu, Shuyang Shi
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Patent number: 10045954Abstract: The invention discloses a use of paracetamol and a pharmaceutical preparation containing the same in preparation of anti-HPV drugs. The novel anti-HPV pharmaceutical preparation of the invention has a significant anti-HPV effect and low toxicity, and can be used for preventing and treating clinical symptoms caused by HPV infection, especially common warts, plane warts, plantar wart, vulvar cancer, penile neoplasms, anal carcinoma, prostate cancer, bladder cancer, cervical cancer, rectal cancer, oral cancer, tonsil cancer and the like.Type: GrantFiled: July 14, 2014Date of Patent: August 14, 2018Assignee: INSTITUTE OF BIOMEDICAL ENGINEERING, CHINESE ACADEMY OF MEDICAL SCIENCEInventors: Tianjun Liu, Shuai Meng, Lihui Zhao, Ge Hong
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Publication number: 20160279081Abstract: The invention discloses a use of paracetamol and a pharmaceutical preparation containing the same in preparation of anti-HPV drugs. The novel anti-HPV pharmaceutical preparation of the invention has a significant anti-HPV effect and low toxicity, and can be used for preventing and treating clinical symptoms caused by HPV infection, especially common warts, plane warts, plantar wart, vulvar cancer, penile neoplasms, anal carcinoma, prostate cancer, bladder cancer, cervical cancer, rectal cancer, oral cancer, tonsil cancer and the like.Type: ApplicationFiled: July 14, 2014Publication date: September 29, 2016Applicant: INSTITUTE OF BIOMEDICAL ENGINEERING CHINESEInventors: Tianjun LIU, Shuai MENG, Lihui ZHAO, Ge HONG
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Publication number: 20100053326Abstract: To solve the defect of the present image sensor used for obtaining both visible information and information indicating variation, such as low frame rate and being not applicable for portable apparatus, the present invention proposed an image sensor, operating method and usage thereof. The image sensor comprises an optoelectronic array, configured to convert optical signals of a first image and reference images at different moments into electronic signals, and the resolution of the optoelectronic array satisfying the requirement of visualization; a first module, configured to read the electronic signals of said first image by way of sampling, to read the electronic signals of each of said reference images by way of sampling, and to obtain the information indicating variation of the first image with respect to the reference images; and a second module, configured to read at least part of the electronic signals of one or more images, and to obtain at least part of visible information of the one or more images.Type: ApplicationFiled: September 2, 2009Publication date: March 4, 2010Applicant: GalaxyCore Inc.Inventors: Lihui Zhao, Lixin Zhao