Patents by Inventor Liisa Koski

Liisa Koski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of eukaryotic genes affecting cell cycle control or cell cycle progression for diagnosis and treatment of proliferative diseases
    Patent number: 7648827
    Abstract: The present invention relates to the significant functional role of several C. elegans genes and of their corresponding gene products in cell cycle progression during cell division that could be identified by means of RNA-mediated interference (RNAi) and to the identification and isolation of functional orthologs of said genes including all biologically functional derivatives thereof. The invention further relates to the use of said genes and gene products (including said orthologs) in the development or isolation of anti-proliferative agents, particularly their use in appropriate screening assays, and their use for diagnosis and treatment of proliferative and other diseases. In particular, the invention relates to the use of small interfering RNAs derived from said genes for the treatment of proliferative diseases.
    Type: Grant
    Filed: September 15, 2004
    Date of Patent: January 19, 2010
    Assignee: Cenix BioScience GmbH
    Inventors: Christophe Echeverri, Anthony Hyman, Pierre Gönczy, Birte Sönnichsen, Steven Jones, Andrew Walsh, Liisa Koski
  • Use of eukaryotic genes affecting spindle formation or microtubule function during cell division for diagnosis and treatment of proliferative diseases
    Patent number: 7479369
    Abstract: The present invention relates to the significant functional role of several C. elegans genes and of their corresponding gene products in spindle formation or microtubule function during cell division that could be identified by means of RNA-mediated interference (RNAi) and to the identification and isolation of functional orthologs of said genes including all biologically functional derivatives thereof The invention further relates to the use of said genes and gene products (including said orthologs) in the development or isolation of anti-proliferative agents, particularly their use in appropriate screening assays, and their use for diagnosis and treatment of proliferative and other diseases. In particular, the invention relates to the use of small interfering RNAs derived from said genes for the treatment of proliferative diseases.
    Type: Grant
    Filed: September 15, 2004
    Date of Patent: January 20, 2009
    Assignee: Cenix BioScience GmbH
    Inventors: Christophe Echeverri, Anthony Hyman, Pierre Gönczy, Birte Sönnichsen, Steven Jones, Andrew Walsh, Liisa Koski
  • Use of eukaryotic genes affecting spindle formation or microtubule function during cell division for diagnosis and treatment of proliferative diseases
    Publication number: 20070093438
    Abstract: The present invention relates to the significant functional role of several C. elegans genes and of their corresponding gene products in spindle formation or microtubule function during cell division that could be identified by means of RNA-mediated interference (RNAi) and to the identification and isolation of functional orthologs of said genes including all biologically functional derivatives thereof The invention further relates to the use of said genes and gene products (including said orthologs) in the development or isolation of anti-proliferative agents, particularly their use in appropriate screening assays, and their use for diagnosis and treatment of proliferative and other diseases. In particular, the invention relates to the use of small interfering RNAs derived from said genes for the treatment of proliferative diseases.
    Type: Application
    Filed: September 15, 2004
    Publication date: April 26, 2007
    Applicant: Cenix BioScience GMbH
    Inventors: Christophe Echeverri, Anthony Hyman, Pierre Gonczy, Birte Sonnichsen, Steven Jones, Andrew Walsh, Liisa Koski
  • Use of eukaryotic genes affecting chromatin separation for diagnosis and treatment of proliferative diseases
    Publication number: 20070042981
    Abstract: The present invention relates to the significant functional role of several C. elegans genes and of their corresponding gene products in chromatin separation during cell division that could be identified by means of RNA-mediated interference (RNAi) and to the identification and isolation of functional orthologs of said genes including all biologically functional derivatives thereof. The invention further relates to the use of said genes and gene products (including said orthologs) in the development or isolation of anti-proliferative agents, particularly their use in appropriate screening assays, and their use for diagnosis and treatment of proliferative and other diseases. In particular, the invention relates to the use of small interfering RNAs derived from said genes for the treatment of proliferative diseases.
    Type: Application
    Filed: September 15, 2004
    Publication date: February 22, 2007
    Applicant: Cenix BioScience GmbH
    Inventors: Christophe Echeverri, Anthony Hyman, Pierre Gonczy, Birte Sonnichsen, Steven Jones, Andrew Walsh, Liisa Koski
  • Use of eukaryotic genes affecting cell cycle control or cell cycle progression for diagnosis and treatment of proliferative diseases
    Publication number: 20070015161
    Abstract: The present invention relates to the significant functional role of several C. elegans genes and of their corresponding gene products in cell cycle progression during cell division that could be identified by means of RNA-mediated interference (RNAi) and to the identification and isolation of functional orthologs of said genes including all biologically functional derivatives thereof. The invention further relates to the use of said genes and gene products (including said orthologs) in the development or isolation of anti-proliferative agents, particularly their use in appropriate screening assays, and their use for diagnosis and treatment of proliferative and other diseases. In particular, the invention relates to the use of small interfering RNAs derived from said genes for the treatment of proliferative diseases.
    Type: Application
    Filed: September 15, 2004
    Publication date: January 18, 2007
    Applicant: Cenix BioScience GmbH
    Inventors: Christophe Echeverri, Anthony Hynan, Pierry Gonczy, Birte Sonnichsen, Steven Jones, Andrew Walsh, Liisa Koski