Abstract: Described is a light emitting diode (LED) that uses hybrid nanostructures to enhance light emission intensity and light extraction efficiency. In at least one embodiment, nanostructures comprise a combination of metal and metal oxide layers that simultaneously provide optical property for emission enhancement and support electrical property for charge transport to support electroluminescence. In at least one embodiment, LED comprises multiple layers including a hybrid metal-metal oxide layer, light-emissive layer, and a light outcoupling layer. In at least one embodiment, metal-metal oxide layer can be formed by evaporation or sputtering. In at least one embodiment, light-emissive layer can be formed by emissive layer spin coating. In at least one embodiment, light outcoupling layer is formed by imprinting or by particle lithography.

Abstract: Disclosed herein is an electrochemical biosensor comprising at least one working electrode on an electrically insulative substrate. At least one working electrode incorporates an electrocatalytic film, comprising a molecularly imprinted polymer (MIP) layer. In at least one embodiment, MIP layer comprises a plurality of shape-selective cavities and a plurality of non-biological electrocatalytic centers.

Abstract: Disclosed probes comprise metal nanoparticle cores associated with magnetic particles that allow probes associated with targets to be concentrated by an applied magnetic field to increase detection sensitivity and provide sufficient spacing between concentrated probes to avoid signal quenching. The probe may comprise at least one recognition receptor, and may further comprise at least one reporter molecule, such as a fluorescent tag, a Raman reporter, or combinations thereof. Concentrating probe-target composites substantially enhances a sensing signal, such as from 5 to 10 times, compared to detection without concentrating the probes. The method may be used to detect, for example, interleukins at concentrations at least as low as 25 pg/ml in sputum or blood from a subject for early and precise profiling of viral infections, such as SARS-CoV-2 infections.

Abstract: Disclosed herein are materials and a micro-LED display with carbon-based light-emitting materials, carbon quantum dots, that are made by a solvothermal synthesis of a mixture of aromatic amino acid, 3,4-dihydroxy-L-phenylalanine (LDOPA), and urea in dimethylformamide (DMF). The mixture is heated in a sealed pressure reactor at a temperature, ranging from 120 degrees Celsius to 350 degrees Celsius, for 4-24 hours. The product is then purified to collect the solid powder. The purified CDs can be dissolved in an acrylate monomer solution or a polymer solution for material delivery and curing process on a target substrate for the applications, including light-emitting devices or sensors.

Abstract: A light emitting diode (LED) apparatus is described that applies plasmonic nanoparticles to enhance multicolor emitting materials, such as quantum dots (QDs) or fluorophores, in the color conversion layer of micro-LED and suppress the UV transmission. The metal nanoparticles, including but not limited to, aluminum, gold, copper, platinum, and silver have surface plasmon resonances in or close to the wavelength of excitation light or the wavelength of emission colors. UV or blue excitation over a color conversion layer formed by the mixture of emitting materials and scattering nanoparticles leads to enhancement of emission and thus increase in their quantum efficiency. An excitation filter is also used with in the LED apparatus to block the transmission of UV or blue excitation.

Abstract: A DNA/RNA detection technology is provided. The open flow detection technique includes a substrate defining a pair of opposing microchannels, a pair of opposing electrodes in the opposing microchannels, and at least one ion exchanging nanomembrane coupled between the opposing microchannels such that the opposing microchannels are connected to each other only through the nanomembrane, wherein the nanomembrane is functionalized with a probe complementary to the macromolecule. A voltammeter is provided to measure the electrical current or potential across the nanomembrane, and detect a change in the measured electrical current or potential to quantify the presence of the macromolecule.

Abstract: A DNA/RNA detection technology is provided. The open flow detection technique includes a substrate defining a pair of opposing microchannels, a pair of opposing electrodes in the opposing microchannels, and at least one ion exchanging nanomembrane coupled between the opposing microchannels such that the opposing microchannels are connected to each other only through the nanomembrane, wherein the nanomembrane is functionalized with a probe complementary to the macromolecule.

Abstract: A DNA/RNA detection technology is provided. The open flow detection technique includes a substrate defining a pair of opposing microchannels, a pair of opposing electrodes in the opposing microchannels, and at least one ion exchanging nanomembrane coupled between the opposing microchannels such that the opposing microchannels are connected to each other only through the nanomembrane, wherein the nanomembrane is functionalized with a probe complementary to the macromolecule.

Abstract: A support for immobilizing target molecules comprises a substrate having a plurality of binding regions for binding select target molecules, with target-molecule-capturing agent immobilized at the binding regions. The binding regions are intersperse among other non-binding regions. The binding regions are of sub-micron size, have high selectivity and high binding capacity, and prevent or at least minimize loss of target molecule activity.

Abstract: A support for immobilizing target molecules comprises a substrate having a plurality of binding regions for binding select target molecules, with target-molecule-capturing agent immobilized at the binding regions. The binding regions are intersperse among other non-binding regions. The binding regions are of sub-micron size, have high selectivity and high binding capacity, and prevent or at least minimize loss of target molecule activity.

Abstract: The present invention proposes a crystallization method of the poly-Si thin film in a thin film transistor. A substrate having an insulator layer is provided. An amorphous silicon layer or a micro-crystalline silicon layer having two thickness is first formed on the insulator layer. The region of thinner is defined as the channel region of the TFT, while the region of thicker can be defined as the source/drain regions of the TFT. Next, an excimer laser is used for crystallization. During the excimer laser irradiation, the amorphous silicon layer of thinner is completely melted, and the amorphous silicon layer of thicker is partially melted. The partially melted amorphous silicon layer is used as crystallization seeds.

Abstract: The present invention proposes a crystallization method of the poly-Si thin film in a thin film transistor. A substrate having an insulator layer is provided. An amorphous silicon layer or a micro-crystalline silicon layer having two thickness is first formed on the insulator layer. The region of thinner is defined as the channel region of the TFT, while the region of thicker can be defined as the source/drain regions of the TFT. Next, an excimer laser is used for crystallization. During the excimer laser irradiation, the amorphous silicon layer of thinner is completely melted, and the amorphous silicon layer of thicker is partially melted. The partially melted amorphous silicon layer is used as crystallization seeds.