Abstract: The embodiments of the present disclosure provide an antibody or antigen-binding fragment against SARS-CoV-2 spike(S) protein, comprising: three complementarity determining regions (HCDRs) of a heavy chain variable region or one or more variants thereof, the heavy chain variable region set forth as SEQ ID NO. 30 or SEQ ID NO. 46, each of the one or more variants having at most two amino acid changes compared to the corresponding CDR; and three complementarity determining regions (LCDRs) of a light chain variable region or one or more variants thereof, the light chain variable region set forth as SEQ ID NO. 32 or SEQ ID NO. 48, each of the one or more variants having at most two amino acid changes compared to the corresponding CDR.

Abstract: The present disclosure discloses an optical imaging system, along an optical axis from an object side to an image side, sequentially includes: a first lens having negative refractive power; a second lens having positive refractive power, and an object-side surface of the second lens being a convex surface; a third lens having refractive power; and a fourth lens having refractive power, and an object-side surface of the fourth lens being a concave surface. A total effective focal length f of the optical imaging system and half of a maximum field-of-view Semi-FOV of the optical imaging system satisfy: f×tan(Semi-FOV)?4.0 mm; and the total effective focal length f of the optical imaging system and an entrance pupil diameter EPD of the optical imaging system satisfy: f/EPD<2.35.

Abstract: An optical imaging lens assembly is provided, which includes, sequentially from an object side to an image side along an optical axis, a first lens having a refractive power with a convex object-side surface; a second lens having a refractive power with a convex object-side surface; a third lens having a positive refractive power; a fourth lens having a negative refractive power with a concave object-side surface; a fifth lens having a refractive power; and a sixth lens having a refractive power. A half of a maximal field-of-view Semi-FOV of the optical imaging lens assembly satisfies: Semi-FOV?70°. A half of a diagonal length ImgH of an effective pixel area on the imaging plane of the optical imaging lens assembly satisfies: ImgH?7.8 mm.