Patents by Inventor Lili Mitchell

Lili Mitchell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RNA POLYMERASES
    Publication number: 20260218263
    Abstract: The present disclosure relates, according to some embodiments, to RNA polymerases and fusions, compositions, kits, methods, and workflows including RNA polymerases. According to some embodiments, an RNA polymerase may include an H6 RNA polymerase (e.g., SEQ ID NO: 21) and/or variants thereof (e.g., variants having ?90%, ?95%, ?98% to any of SEQ ID NOS: 1-20 and/or 22).
    Type: Application
    Filed: March 12, 2026
    Publication date: July 30, 2026
    Applicant: New England Biolabs, Inc.
    Inventors: Jackson A. Buss, Vladimir Potapov, Peter R. Weigele, Jennifer Ong, Lili Mitchell, Dillon B. Nye, Tien-Hao Chen, G. B. Robb
  • Compositions, kits, and methods for in vitro transcription
    Patent number: 12492420
    Abstract: The present disclosure relates, according to some embodiments, to cold-active RNA polymerases, variants thereof, compositions and kits comprising cold-active RNA polymerases, and methods of using cold-active RNA polymerases. Cold-active polymerases may have, for example, an amino acid sequence ?90%, ?91%, ?92%, ?93%, ?94%, ?95%, ?96%, ?97%, ?98%, ?99% identical (e.g., ?95% or ?98% identical) to any of SEQ ID NOS: 1-19 and optionally may have at least one substitution relative to SEQ ID NO:1.
    Type: Grant
    Filed: March 31, 2025
    Date of Patent: December 9, 2025
    Inventors: Dillon B. Nye, Jennifer L. Curcuru, Tien-Hao Chen, Lili Mitchell, Ivan R. Correa, Jr.
  • COMPOSITIONS, KITS, AND METHODS FOR IN VITRO TRANSCRIPTION
    Publication number: 20250305019
    Abstract: The present disclosure relates, according to some embodiments, to cold-active RNA polymerases, variants thereof, compositions and kits comprising cold-active RNA polymerases, and methods of using cold-active RNA polymerases. Cold-active polymerases may have, for example, an amino acid sequence ?90%, ?91%, ?92%, ?93%, ?94%, ?95%, ?96%, ?97%, ?98%, ?99% identical (e.g., ?95% or ?98% identical) to any of SEQ ID NOS: 1-19 and optionally may have at least one substitution relative to SEQ ID NO:1.
    Type: Application
    Filed: March 31, 2025
    Publication date: October 2, 2025
    Applicant: New England Biolabs, Inc.
    Inventors: Dillon B. Nye, Jennifer L. Curcuru, Tien-Hao Chen, Lili Mitchell, Ivan R. Correa, JR.