Patents by Inventor Lilia M. Beauchamp

Lilia M. Beauchamp has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted 5-alkynyl pyrimidines having neurotrophic activity
    Patent number: 7205297
    Abstract: The present invention relates to a series of novel substituted 5-alkynyl pyrimidines, pharmaceutical compositions which contain them, methods for their preparation, and their use in therapy, particularly in the treatment of neurodegenerative or other neurological disorders of the central and peripheral nervous systems, including age related cognitive disorders such as senility and Alzheimer's disease, nerve injuries, peripheral neuropathies, and seizure disorders such as epilepsy.
    Type: Grant
    Filed: July 20, 2001
    Date of Patent: April 17, 2007
    Assignee: Krenitsky Pharmaceuticals, Inc.
    Inventors: Lilia M. Beauchamp, Thomas A. Krenitsky, James L. Kelley
  • Neurotrophic substituted pyrimidines
    Patent number: 6916820
    Abstract: The present invention relates to a series of substituted pyrimidines, to pharmaceutical compositions which contain them, to methods for their preparation and to their use in therapy, particularly in the treatment of neurodegenerative or other neurological disorders of the central and peripheral nervous systems.
    Type: Grant
    Filed: April 6, 2000
    Date of Patent: July 12, 2005
    Assignee: Krenitsky Pharmaceuticals, Inc.
    Inventors: James L. Kelley, Thomas A. Krenitsky, Lilia M. Beauchamp
  • Substituted 5-alkynyl pyrimidines having neurotrophic activity
    Publication number: 20040087789
    Abstract: The present invention relates to a series of novel substituted 5-alkynyl pyrimidines, pharmaceutical compositions which contain them, methods for their preparation, and their use in therapy, particularly in the treatment of neurodegenerative or other neurological disorders of the central and peripheral nervous systems, including age related cognitive disorders such as senility and Alzheimer's disease, nerve injuries, peripheral neuropathies, and seizure disorders such as epilepsy.
    Type: Application
    Filed: June 27, 2003
    Publication date: May 6, 2004
    Inventors: Lilia M. Beauchamp, Thomas A. Krenitsky, James L. Kelley
  • Neurotrophic substituted pyrimidines
    Patent number: 6583148
    Abstract: The present invention relates to novel derivatives of a series of substituted pyrimidines, to pharmaceutical compositions which contain them, to methods for their preparation and to their use in therapy, particularly in the treatment of neurodegenerative or other neurological disorders of the central and peripheral systems.
    Type: Grant
    Filed: April 8, 1999
    Date of Patent: June 24, 2003
    Assignee: Krenitsky Pharmaceuticals, Inc.
    Inventors: James L. Kelley, Thomas A. Krenitsky, Lilia M. Beauchamp
  • Substituted pyrimidine derivatives, their preparation and their use in the treatment of neurodegenerative or neurological disorders of the central nervous system
    Patent number: 6440965
    Abstract: The present invention relates to novel derivatives of a series of substituted pyrimidines, to pharmaceutical compositions which contain them, to methods for their preparation and to their use in therapy, particularly in the treatment of neurodegenerative or other neurological disorders of the central and peripheral systems.
    Type: Grant
    Filed: April 14, 2000
    Date of Patent: August 27, 2002
    Assignee: Krenitsky Pharmaceuticals, Inc.
    Inventors: James L. Kelley, Thomas A. Krenitsky, Lilia M. Beauchamp
  • Antiviral compounds
    Patent number: 5318974
    Abstract: The present invention relates to amino acid esters of pyrimidine and purine nucleosides containing an acyclic side chain, and their use in medical therapy, particularly the treatment of herpes virus infections. Also provided are pharmaceutical formulations and processes for the preparation of compounds according to the invention.
    Type: Grant
    Filed: March 5, 1992
    Date of Patent: June 7, 1994
    Assignee: Burroughs Wellcome Co.
    Inventor: Lilia M. Beauchamp
  • Therapeutic compounds
    Patent number: 5079252
    Abstract: The present invention relates to the valeryl ester of acyclovir and pharmacologically acceptable salts thereof and their use in medical therapy particularly in the treatment of viral infections. Also provided are processes for the preparation and pharmaceutical formulations containing the compounds according to the invention.
    Type: Grant
    Filed: July 13, 1989
    Date of Patent: January 7, 1992
    Assignee: Buroughs Welcome Co.
    Inventor: Lilia M. Beauchamp
  • 2-amino purine derivatives
    Patent number: 5059604
    Abstract: A group of 2-aminopurine compounds, which have in the 6-position a hydrogen and in the 9-position an acyclic moiety ##STR1## wherein X is oxygen or sulphur and Y is hydrogen or CH.sub.2 OH (provided than when X is oxygen Y may not be hydrogen), are converted enzymatically in vivo into the corresponding 6-hydroxy (i.e. guanine) derivatives which are potent antiviral compounds. The enzymatic conversion may also be effected ex vivo (i.e. in vitro) as a method of synthesizing the corresponding 6-hydroxy derivatives.
    Type: Grant
    Filed: January 27, 1984
    Date of Patent: October 22, 1991
    Assignee: Burroughs Wellcome Co.
    Inventors: Thomas A. Krenitsky, Lilia M. Beauchamp
  • Antiviral compounds
    Patent number: 5043339
    Abstract: The present invention relates to amino acid esters of pyrimidine and purine nucleosides containing an acyclic side chain, and their use in medical therapy, particularly the treatment of herpes virus infections. Also provided are pharmaceutical formulations and processes for the preparation of compounds according to the invention.
    Type: Grant
    Filed: December 18, 1989
    Date of Patent: August 27, 1991
    Assignee: Burroughs Wellcome Co.
    Inventor: Lilia M. Beauchamp
  • Therapeutic valine esters of acyclovir and pharmaceutically acceptable salts thereof
    Patent number: 4957924
    Abstract: The present invention relates to certain amino acid exters of the purine nucleoside acyclovir, pharmaceutically acceptable salts thereof and their use in the treatment of herpes virus infections. The invention also includes pharmaceutical formulations and processes for the preparation of such compounds.
    Type: Grant
    Filed: August 4, 1988
    Date of Patent: September 18, 1990
    Assignee: Burroughs Wellcome Co.
    Inventor: Lilia M. Beauchamp
  • Antiviral compounds
    Patent number: 4714701
    Abstract: Compounds of formula (I) ##STR1## (wherein A represents a ##STR2## grouping; R.sup.1 represents a hydrogen or halogen (e.g. chlorine or bromine) atom or a hydroxy or amino group, R.sup.2 represents a hydrogen atom or a C.sub.1-4 alkyl (e.g. methyl) group, X represents an oxygen or sulphur group and m and n are each 0 or 1 provided that m+n=1) and physiologically acceptable salts and esters thereof, have been found to have potent antiviral activity particularly against herpes infections.
    Type: Grant
    Filed: May 2, 1986
    Date of Patent: December 22, 1987
    Assignee: Burroughs Wellcome Co.
    Inventor: Lilia M. Beauchamp