Patents by Inventor Liliane Massade

Liliane Massade has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antisense RNA targeting PMP22 for the treatment of Charcot-Marie-Tooth 1A disease
    Patent number: 11939577
    Abstract: The present invention relates to antisense RNAs targeting PMP22 and able to inhibit from 40% to 60% the expression of PMP22 in the cells and a pharmaceutical composition comprising thereof. The antisense RNAs are preferably siRNA and are preferably provided in the form of nanoparticles. The present invention also relates to the use of these antisense RNAs targeting PMP22 for the treatment of Charcot-Marie-Tooth 1A disease.
    Type: Grant
    Filed: September 24, 2019
    Date of Patent: March 26, 2024
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)
    Inventors: Liliane Massade, Charbel Massaad, Susan Boutary, Giorgia Maria Laura Urbinati, Patrick Couvreur, Didier Desmaële
  • ANTISENSE RNA TARGETING PMP22 FOR THE TREATMENT OF CHARCOT-MARIE-TOOTH 1A DISEASE
    Publication number: 20220002721
    Abstract: The present invention relates to antisense RNAs targeting PMP22 and able to inhibit from 40% to 60% the expression of PMP22 in the cells and a pharmaceutical composition comprising thereof. The antisense RNAs are preferably siRNA and are preferably provided in the form of nanoparticles. The present invention also relates to the use of these antisense RNAs targeting PMP22 for the treatment of Charcot-Marie-Tooth 1A disease.
    Type: Application
    Filed: September 24, 2019
    Publication date: January 6, 2022
    Inventors: Liliane MASSADE, Charbel MASSAAD, Susan BOUTARY, Giorgia Maria Laura URBINATI, Patrick COUVREUR, Didier DESMAËLE
  • NOVEL NUCLEIC ACID TRANSFER SYSTEM
    Publication number: 20110184053
    Abstract: The invention relates to a complex formed by at least one molecule of nucleic acid comprising between 10 and 40 nucleotides, covalently coupled to at least one hydrocarbon compound that is at least C18 is hydrocarbon compound, having a squalene structure or a structure similar thereto.
    Type: Application
    Filed: May 14, 2009
    Publication date: July 28, 2011
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE PARIS SUD
    Inventors: Patrick Couvreur, Didier Desmaele, Mouna Raouane, Liliane Massade, Claude Malvy