Patents by Inventor Liling Wan

Liling Wan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INHIBITORS OF ENL/AF9 YEATS
    Publication number: 20230027198
    Abstract: Methods and compositions for treating leukemia are disclosed. Acylated 6-aminoindoles, acylated 6-aminopyrrolopyridines and acylated 3-aminopyrrolo[3,2-c]pyridazines of the following formula inhibit ENL/AF9 YEATS and are therefore useful for treating leukemia.
    Type: Application
    Filed: December 17, 2020
    Publication date: January 26, 2023
    Inventors: Tanweer A. KHAN, Nigel LIVERTON, Yoshiyuki FUKASE, Mayako MICHINO, Andrew W. STAMFORD, Michael W. MILLER, David HUGGINS, Peter MEINKE, David C. ALLIS, Liling WAN, Tammy LADDUWAHETTY, Joseph VACCA
  • Use of peptides that block metadherin-SND1 interaction as treatment for cancer
    Patent number: 10786545
    Abstract: The present disclosure related in general to methods of treating cancer by interfering with the interaction of metadherin with Staphylococcal nuclease domain-containing 1 (SND1) using peptides or other compounds that inhibit the binding of SND1 with metadherin and inhibit the activity of the MTDH-SND1 complex in tumor cells.
    Type: Grant
    Filed: May 8, 2019
    Date of Patent: September 29, 2020
    Assignees: The Trustees of Princeton University, Wisconsin Alumni Research Foundation
    Inventors: Yibin Kang, Yongna Xing, Liling Wan, Feng Guo
  • Use of Peptides That Block Metadherin-SND1 Interaction as Treatment for Cancer
    Publication number: 20190336574
    Abstract: The present disclosure related in general to methods of treating cancer by interfering with the interaction of metadherin with Staphylococcal nuclease domain-containing 1 (SND1) using peptides or other compounds that inhibit the binding of SND1 with metadherin and inhibit the activity of the MTDH-SND1 complex in tumor cells.
    Type: Application
    Filed: May 8, 2019
    Publication date: November 7, 2019
    Inventors: Yibin Kang, Yongna Xing, Liling Wan, Feng Guo
  • Use of peptides that block metadherin-SND1 interaction as treatment for cancer
    Patent number: 10357539
    Abstract: The present disclosure related in general to methods of treating cancer by interfering with the interaction of metadherin with Staphylococcal nuclease domain-containing 1 (SND1) using peptides or other compounds that inhibit the binding of SND1 with metadherin and inhibit the activity of the MTDH-SND1 complex in tumor cells.
    Type: Grant
    Filed: June 25, 2015
    Date of Patent: July 23, 2019
    Assignees: The Trustees of Princeton University, Wisconsin Alumni Research Foundation
    Inventors: Yibin Kang, Yongna Xing, Liling Wan, Feng Guo
  • USE OF PEPTIDES THAT BLOCK METADHERIN- SND1 INTERACTION AS TREATMENT FOR CANCER
    Publication number: 20170189481
    Abstract: The present disclosure related in general to methods of treating cancer by interfering with the interaction of metadherin with Staphylococcal nuclease domain-containing 1 (SND1) using peptides or other compounds that inhibit the binding of SND1 with metadherin and inhibit the activity of the MTDH-SND1 complex in tumor cells.
    Type: Application
    Filed: June 25, 2015
    Publication date: July 6, 2017
    Inventors: Yibin Kang, Yongna Xing, Liling Wan, Feng Guo