Patents by Inventor Lilli M. Petruzzelli

Lilli M. Petruzzelli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Administration of NEDD8-Activating Enzyme Inhibitor
    Publication number: 20140249167
    Abstract: Disclosed are methods for the treatment of patients with diseases, disorders or conditions responsive to the inhibition of NAE (Nedd8-activating enzyme), e.g., cancer. The methods comprise administering a clinically effective amount of the NAE-inhibitor ((1S,2S,4R)-4-(4-((1S)-2,3-dihydro-1H-inden-1-ylamino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentyl)methyl sulfamate (MLN4924) according to an intermittent dosing regimen in which there is a rest period of at least two days between each administration.
    Type: Application
    Filed: October 8, 2013
    Publication date: September 4, 2014
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Bruce J. Dezube, Lilli M. Petruzzelli
  • ADMINISTRATION OF NEDD8-ACTIVATING ENZYME INHIBITOR
    Publication number: 20120115892
    Abstract: Disclosed are methods for the treatment of patients with diseases, disorders or conditions responsive to the inhibition of NAE (Nedd8-activating enzyme), e.g., cancer. The methods comprise administering a clinically effective amount of the NAE-inhibitor ((1S,2S,4R)-4-(4-((1S)-2,3-dihydro-1H-inden-1-ylamino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentyl)methyl sulfamate (MLN4924) according to an intermittent dosing regimen in which there is a rest period of at least two days between each administration.
    Type: Application
    Filed: November 3, 2011
    Publication date: May 10, 2012
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Bruce J. Dezube, Lilli M. Petruzzelli