Patents by Inventor Lillian Cromie
Lillian Cromie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9399013Abstract: An aqueous pharmaceutical suspension comprising: (i) at least one non-steroidal anti-inflammatory drug; (ii) an aqueous buffer system; (iii) xanthan gum; (iv) polyvinyl pyrrolidone; and (v) glycerol wherein the suspension is free from pregelatinized starch, amino polycarboxylic acid, microcrystalline cellulose, hydroxypropylmethyl cellulose, polyoxyethylene sorbitan monooleate, silicon dioxide and taste modifying agents selected from the group consisting of bulk sweeteners, intense sweeteners, flavoring agents and mixtures thereof.Type: GrantFiled: May 10, 2007Date of Patent: July 26, 2016Assignee: Norbrook Laboratories LimitedInventors: William Blakely, Louise Reynolds, Lillian Cromie
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Patent number: 9289380Abstract: A composition prepared for treating animals suffering from parasites which parasites are known to be susceptible to at least one of the avermectins, milbemycins or salicylanilides, comprises for example ivermectin in an amount of from 0.1 to 10%(w/v), a solvent selected from the group consisting of glycerol formal, propylene glycol, polyethylene glycol and combinations thereof, and a salicylanilide such as closantel in a required dosage amount for the animal to be treated, typically about 2.5 mg/kg live weight of the animal to be treated, a polymeric species selected from the group consisting of polyvinylpyrrolidone and polyoxypropylene/polyoxyethylene block copolymers, the said polymeric species improving the bioavailability of closantel to the extend that blood plasma levels of the said compound greater than about 20 ppm over period of treatment are achievable.Type: GrantFiled: February 12, 2003Date of Patent: March 22, 2016Assignee: Norbrook Laboratories LimitedInventors: William Blakely, Lillian Cromie, Sean Duffy
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Publication number: 20150224195Abstract: A topical ectoparasiticide composition comprising an Insect Growth Regulator and at least one C6-C12 medium chain triglyceride wherein the composition comprises at least 60% (w/v) of the triglyceride based on the total composition.Type: ApplicationFiled: March 11, 2015Publication date: August 13, 2015Inventors: William Blakely, Lillian Cromie
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Patent number: 8993546Abstract: An anti-parasiticidal composition presented as a topical “pour-on” product for treating animals infected by parasites which are known to be susceptible to salicylanilides, especially closantel, alone or together with at least one other anti parasitic compound of the avermectin or milbemycin type and offers enhanced bioavailability of the salicylanilide by provision of a delivery system comprising at least 20% (v/v) of one or more alcohols, and optionally including a polymeric moiety selected from the group consisting of polyvinylpyrrolidone (PVP), polyoxypropylene/polyoxyethylene block copolymers (poloxamer), and polyethylene glycols (PEG), thereby improving the bioavailability of e.g. closantel (as assessed with respect to blood plasma levels of closantel).Type: GrantFiled: January 12, 2006Date of Patent: March 31, 2015Assignee: Norbrook Laboratories LimitedInventors: William Blakely, Lillian Cromie
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Patent number: 8216183Abstract: A heating device (1) is described for a container (7) of a liquid pharmaceutical product having a viscosity of 50-500 cP at 4° C. and contained within a glass container. The device (1) comprises a substantially rigid, thin-walled housing (2) defining an openable chamber for receiving the container (7), a heat source (6) in the chamber comprising a hermetically sealed package containing a super-cooled metal salt fluid or liquid and an actuator (14) for activating the super-cooled metal salt to produce heat, wherein the ratio of the volume of the metal salt to the intended volume of the product is no more than 1:1.Type: GrantFiled: July 21, 2008Date of Patent: July 10, 2012Assignee: Norbrook Laboratories LimitedInventors: William Blakeley, Michael Lanigan, Lillian Cromie
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Publication number: 20110288039Abstract: A topical ectoparasiticide composition comprising an Insect Growth Regulator and at least one C6-C12 medium chain triglyceride wherein the composition comprises at least 60% (w/v) of the triglyceride based on the total composition.Type: ApplicationFiled: March 11, 2009Publication date: November 24, 2011Inventors: William Blakely, Lillian Cromie
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Patent number: 8008480Abstract: A process for purifying meloxicam form I from a crude meloxicam, which comprises: i. contacting the crude meloxicam with an amine in a non-aqueous solvent to form a meloxicam salt; ii. isolating the meloxicam salt; iii. dissolving the meloxicam salt in an aqueous solvent to form a salt solution; and iv. adding an acid to the salt solution to precipitate free meloxicam.Type: GrantFiled: March 2, 2009Date of Patent: August 30, 2011Assignee: Norbrook Laboratories LtdInventors: Liam McElroy, Lillian Cromie, Mark Garret
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Publication number: 20110166517Abstract: A heating device (1) is described for a container (7) of a liquid pharmaceutical product having a viscosity of 50-500 cP at 4° C. and contained within a glass container. The device (1) comprises a substantially rigid, thin-walled housing (2) defining an openable chamber for receiving the container (7), a heat source (6) in the chamber comprising a hermetically sealed package containing a super-cooled metal salt fluid or liquid and an actuator (14) for activating the super-cooled metal salt to produce heat, wherein the ratio of the volume of the metal salt to the intended volume of the product is no more than 1:1.Type: ApplicationFiled: July 21, 2008Publication date: July 7, 2011Inventors: William Blakeley, Michael Lanigan, Lillian Cromie
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Patent number: 7879899Abstract: An injectable aqueous composition for veterinary use containing a non-steroidal anti-inflammatory compound in an amount of from about 0.25 to 30% (w/v) together with a physiologically acceptable oxygenated polymeric surfactant in an amount of from about 0.5 to 20% (w/v).Type: GrantFiled: March 31, 2003Date of Patent: February 1, 2011Assignee: Norbrook Laboratories LimitedInventors: William Blakely, Lillian Cromie, Sean Duffy
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Publication number: 20090186883Abstract: An aqueous pharmaceutical suspension comprising: (i) at least one non-steroidal anti-inflammatory drug; (ii) an aqueous buffer system; (iii) xanthan gum; (iv) polyvinyl pyrrolidone; and (v) glycerol wherein the suspension is free from pregelatinised starch, amino polycarboxylic acid, microcrystalline cellulose, hydroxypropylmethyl cellulose, polyoxyethylene sorbitan monooleate, silicon dioxide and taste modifying agents selected from the group consisting of bulk sweeteners, intense sweeteners, flavouring agents and mixtures thereof.Type: ApplicationFiled: May 10, 2007Publication date: July 23, 2009Inventors: William Blakely, Louise Reynolds, Lillian Cromie
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Publication number: 20090163707Abstract: A process for purifying meloxicam form I from a crude meloxicam, which comprises: i. contacting the crude meloxicam with an amine in a non-aqueous solvent to form a meloxicam salt; ii. isolating the meloxicam salt; iii. dissolving the meloxicam salt in an aqueous solvent to form a salt solution; and iv. adding an acid to the salt solution to precipitate free meloxicam.Type: ApplicationFiled: March 2, 2009Publication date: June 25, 2009Inventors: Liam McElroy, Lillian Cromie, Mark Garret
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Publication number: 20080206378Abstract: A topical formulation comprising as active ingredients, at least one effective agent derived from Streptomyces avermitilis, i.e. a macrocylic lactone e.g. an avermectin or chemically modified or synthetic derivative thereof, e.g. ivermectin, together with another anthelmintic of the sulphonamide type, e.g. clorsulon, in a carrier that facilitates topical administration and delivery of the active ingredients transdermal Iy, e.g. a carrier that is useful for this purpose comprises alcoholic solvents, such as ethanol, and isopropanol, with optional excipients and formulation aids, which may comprise a polymeric species such as PVP or a poloxamer.Type: ApplicationFiled: January 19, 2006Publication date: August 28, 2008Inventors: William Blakely, Lillian Cromie
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Publication number: 20080119647Abstract: A process for purifying meloxicam form I from a crude meloxicam, which comprises: i. contacting the crude meloxicam with an amine in a non-aqueous solvent to form a meloxicam salt; ii. isolating the meloxicam salt; iii. dissolving the meloxicam salt in an aqueous solvent to form a salt solution; and iv. adding an acid to the salt solution to precipitate free meloxicam.Type: ApplicationFiled: November 15, 2007Publication date: May 22, 2008Inventors: Liam McElroy, Lillian Cromie, Mark Garret
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Publication number: 20060142216Abstract: An anti-parasiticidal composition presented as a topical “pour-on” product for treating animals infected by parasites which are known to be susceptible to salicylanilides, especially closantel, alone or together with at least one other anti parasitic compound of the avermectin or milbemycin type and offers enhanced bioavailability of the salicylanilide by provision of a delivery system comprising at least 20% (v/v) of one or more alcohols, and optionally including a polymeric moiety selected from the group consisting of polyvinylpyrrolidone (PVP), polyoxypropylene/polyoxyethylene block copolymers (poloxamer), and polyethylene glycols (PEG), thereby improving the bioavailability of e.g. closantel (as assessed with respect to blood plasma levels of closantel).Type: ApplicationFiled: January 12, 2006Publication date: June 29, 2006Inventors: William Blakely, Lillian Cromie
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Patent number: 6925963Abstract: A pet blanket providing anti-flea properties is disclosed. The blanket is formed of an upper, permeable layer and a lower, impermeable layer, which together form a closeable pocket for receiving an insert that is impregnated with one or more anti-flea agents. As a pet reclines on the upper, permeable layer, the anti-flea agent(s) diffuse from the insert, through the permeable layer and onto the supine animal.Type: GrantFiled: April 15, 2004Date of Patent: August 9, 2005Assignee: Norbrook Laboratories LimitedInventors: Sean Duffy, Lillian Cromie, William Blakely
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Publication number: 20050147680Abstract: An injectable aqueous composition for veterinary use containing a non-steroidal anti-inflammatory compound in an amount of from about 0.25 to 30% (w/v) together with a physiologically acceptable oxygenated polymeric surfactant in an amount of from about 0.5 to 20% (w/v).Type: ApplicationFiled: March 31, 2003Publication date: July 7, 2005Inventors: William Blakely, Lillian Cromie, Sean Duffy
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Publication number: 20050118221Abstract: A composition prepared for treating animals suffering from parasites which parasites are known to be susceptible to at least one of the avermectins, milbemycins or salicylanilides, comprises for example ivermectin in an amount of from 0.1 to 10%(w/v), a solvent selected from the group consisting of glycerol formal, propylene glycol, polyethylene glycol and combinations thereof, and a salicylanilide such as closantel in a required dosage amount for the animal to be treated, typically about 2.5 mg/kg live weight of the animal to be treated, a polymeric species selected from the group consisting of polyvinylpyrrolidone and polyoxypropylene/polyoxyethylene block copolymers, the said polymeric species improving the bioavailability of closantel to the extend that blood plasma levels of the said compound greater than about 20 ppm over period of treatment are achievable.Type: ApplicationFiled: February 12, 2003Publication date: June 2, 2005Inventors: William Blakely, Lillian Cromie, Sean Duffy
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Patent number: 6805076Abstract: A pet blanket providing anti-flea properties is disclosed. The blanket is formed of an upper, permeable layer and a lower, impermeable layer, which together form a closeable pocket for receiving an insert that is impregnated with one or more anti-flea agents. As a pet reclines on the upper, permeable layer, the anti-flea agent(s) diffuse from the insert, through the permeable layer and onto the supine animal.Type: GrantFiled: August 7, 2002Date of Patent: October 19, 2004Assignee: Norbrook Laboratories LimitedInventors: Sean Duffy, Lillian Cromie, William Blakely
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Publication number: 20040194730Abstract: A pet blanket providing anti-flea properties is disclosed. The blanket is formed of an upper, permeable layer and a lower, impermeable layer, which together form a closeable pocket for receiving an insert that is impregnated with one or more anti-flea agents. As a pet reclines on the upper, permeable layer, the anti-flea agent(s) diffuse from the insert, through the permeable layer and onto the supine animal.Type: ApplicationFiled: April 15, 2004Publication date: October 7, 2004Applicant: Norbrook Laboratories LimitedInventors: Sean Duffy, Lillian Cromie, William Blakely
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Publication number: 20030010296Abstract: A pet blanket providing anti-flea properties is disclosed. The blanket is formed of an upper, permeable layer and a lower, impermeable layer, which together form a closeable pocket for receiving an insert that is impregnated with one or more anti-flea agents. As a pet reclines on the upper, permeable layer, the anti-flea agent(s) diffuse from the insert, through the permeable layer and onto the supine animal.Type: ApplicationFiled: August 7, 2002Publication date: January 16, 2003Applicant: NORBROOK LABORATORIES LIMITEDInventors: Sean Duffy, Lillian Cromie, William Blakely