Patents by Inventor Lillian Mansbach

Lillian Mansbach has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Simultaneous radioassay of folate and vitamin B12
    Patent number: 4423154
    Abstract: A serum sample is heated at an alkaline pH to release folate and vitamin B.sub.12 from endogenous binders. A simultaneous radioassay for folate and vitamin B.sub.12 is effected by contacting the sample with binder for folate, binder for vitamin B.sub.12, folate labeled with one radioactive isotope and vitamin B.sub.12 labeled with another radioactive isotope, followed by separation of bound and free portions, and determination of the radioactivity of at least one of the portions. The amounts of folate and vitamin B.sub.12 present in the sample may be determined from standard curves.
    Type: Grant
    Filed: February 12, 1981
    Date of Patent: December 27, 1983
    Assignee: Becton Dickinson and Company
    Inventors: Sidney Gutcho, Lillian Mansbach
  • Serum vitamin B.sub.12 assay and kit therefor
    Patent number: 4300907
    Abstract: In a vitamin B.sub.12 assay, serum, containing vitamin B.sub.12 bound to endogenous binders therefor, is released from such endogenous binders by a releasing agent comprised of a water miscible organic liquid, such as, acetone, reducing agent and cyanide ions. Such release can be effected at room temperature, as compared to prior procedures which required heating to elevated temperatures.
    Type: Grant
    Filed: February 4, 1980
    Date of Patent: November 17, 1981
    Assignee: Becton, Dickinson and Company
    Inventors: Lillian Mansbach, Henry McCarter
  • Simultaneous radioassay of folate and vitamin B.sub.12
    Patent number: 4279859
    Abstract: A serum sample is heated at an alkaline pH to release folate and vitamin B.sub.12 from endogenous binders. A simultaneous radioassay for folate and vitamin B.sub.12 is effected by contacting the sample with binder for folate, binder for vitamin B.sub.12, folate labeled with one radioactive isotope and vitamin B.sub.12 labeled with another radioactive isotope, followed by separation of bound and free portions, and determination of the radioactivity of at least one of the portions. The amounts of folate and vitamin B.sub.12 present in the sample may be determined from standard curves.
    Type: Grant
    Filed: June 26, 1978
    Date of Patent: July 21, 1981
    Assignee: Becton Dickinson & Company
    Inventors: Sidney Gutcho, Lillian Mansbach
  • Simultaneous radioassay of folate and vitamin B.sub.12
    Patent number: 4146602
    Abstract: A serum sample is heated at an alkaline pH to release folate and vitamin B.sub.12 from endogenous binders. A simultaneous radioassay for folate and vitamin B.sub.12 is effected by contacting the sample with binder for folate, binder for vitamin B.sub.12, folote labeled with one radioactive isotope and vitamin B.sub.12 labeled with another radioactive isotope, followed by separation of bound and free portions, and determination of the radioactivity of at least one of the portions. The amounts of folate and vitamin B.sub.12 present in the sample may be determined from standard curves.
    Type: Grant
    Filed: July 21, 1977
    Date of Patent: March 27, 1979
    Assignee: Becton, Dickinson & Company
    Inventors: Sidney Gutcho, Lillian Mansbach