Abstract: The invention relates to a tizoxanide carbamate compound of Formula I and a pharmaceutically acceptable salt, a hydrate or a solvate thereof, and their pharmaceutical use.

Abstract: The present invention relates to a compound of formula (I), a stereomeride, pharmaceutically acceptable salt, a solvate or an N-oxide thereof, a medicine composition comprising the compound, a method for preparing the compound, and a usage of the compound in treating diseases related to Hsp70. The diseases are preferably selected from tumors, neurodegenerative diseases, and allogeneic transplantation rejection and infection.

Abstract: Provided are piperazinyl pyrimidine derivatives of formula I having CCR4 antagonism, and the preparation method, pharmaceutical composition and use thereof in the preparation of a medicament. The medicament is useful for the treatment and prevention of CCR4-related diseases.

Abstract: A separator for an oil well produced fluid comprises a housing and a tube group arranged within the housing. The tube group includes a plurality of horizontal pipes in a layered arrangement along a vertical direction, and a plurality of vertical pipes which allows adjacent layers of the horizontal pipes to be in fluid communication with each other. The plurality of horizontal pipes shares an inlet pipe in communication with the outside of the housing, and each of the horizontal pipes has a respective outlet. The separator is configured in such a manner that the horizontal pipes in an upper layer, a middle layer, and a lower layer are respectively used as oil pipes, water pipes, and sediment pipes.

Abstract: In general, techniques are described for ensuring the distribution of Virtual Private Network (VPN) routes in a service provider network configured with multiple VPN services. In some examples, a network device receives configuration data that defines a VPN service associated with a route target. The network device, responsive to receiving the configuration data, sends a request for routes that match a type of the VPN service to a routing protocol speaker. The network device receives routes that match the type of the VPN service and are associated with the route target, installs the routes that match the type of the VPN service and are associated with the route target to the routing information base. The network device forwards traffic for the VPN service in accordance with the installed routes.

Abstract: A method, a device, and a network system of establishing a tunnel are provided in embodiments of the present disclosure. The method of establishing the tunnel includes: obtaining, by a WTP, an address of an AC and an address of a BRAS from a DHCP server; using, by the WTP, the address of the AC to establish a CAPWAP control tunnel with the AC; and using, by the WTP, the address of the BRAS to establish a CAPWAP data tunnel with the BRAS. By using the technical scheme provided in the embodiments of the present disclosure, the CAPWAP data tunnel may be established between the WTP and the BRAS.

Abstract: Techniques are described for utilizing two-part metrics with link state routing protocols of computer networks. For example, link state advertisements communicated by a router convey outbound cost metrics representative of outbound costs for the router to send network traffic to a network, and inbound cost metrics representative of inbound costs to receive network traffic from the network. The techniques may be particularly useful with respect to shared access networks, including broadcast or non-broadcast multi-access networks.

Abstract: The present invention relates to a compound of Formula I, or an isomer, pharmaceutically acceptable salt and solvate of the compound, and to a composition comprising the compound of Formula I, or the isomer, pharmaceutically acceptable salt and solvate thereof, and a pharmaceutically acceptable carrier, excipient or diluents. The present invention also relates to use of the compound of Formula I, or the isomer, pharmaceutically acceptable salt and solvate thereof for combating apoptosis, preventing or treating a disease or disorder associated with apoptosis; and especially use for protecting cardiomyocyte, and for preventing or treating a disease or disorder associated with cardiomyocyte apoptosis.

Abstract: Disclosed is as a substituted thiazolamine derivative represented by Formula I or a pharmaceutically acceptable salt thereof or a hydrate thereof (the definitions of each group in the formula are as presented in the description), and the application thereof in the prevention and/or treatment of viral diseases induced by picornavirus. Also disclosed is a pharmaceutical composition containing the compound.

Abstract: The present disclosure discloses a method and an apparatus for controlling a network traffic path. The method includes: receiving routing advertisement information from a first network to a second network; determining all routing nodes included in a path through which data pass when flowing from the second network to the first network according to the routing advertisement information; and configuring a next hop routing node for each determined routing node, where the next hop routing node is a node in all the routing nodes included in the path and is adjacent to the routing node for which the next hop routing node is configured, and the routing node for which the next hop routing node is configured does not include a routing node of the first network or a routing node of the second network.

Abstract: The present invention relates to a thiazine amide derivative and a pharmaceutical use thereof, and particularly to a compound of formula I (in the formula, variables are as described in the specification), a pharmaceutically acceptable salt, solvate or hydrate thereof. The present invention further relates to a method for preparing the compound, a pharmaceutical composition containing the compound, and a method or use thereof for prevention or treatment of neurodegenerative diseases.

Abstract: A method, a device, and a network system of establishing a tunnel are provided in embodiments of the present disclosure. The method of establishing the tunnel includes: obtaining, by a WTP, an address of an AC and an address of a BRAS from a DHCP server; using, by the WTP, the address of the AC to establish a CAPWAP control tunnel with the AC; and using, by the WTP, the address of the BRAS to establish a CAPWAP data tunnel with the BRAS. By using the technical scheme provided in the embodiments of the present disclosure, the CAPWAP data tunnel may be established between the WTP and the BRAS.

Abstract: The present invention pertains to field of pharmaceutical chemicals, and relates to thiazole inner salt compounds, preparation methods and uses thereof. Specifically, the present invention relates to a compound of Formula I, hydrates or pharmaceutically acceptable salts thereof. The compound of Formula I of the present invention is a potent cross-linking protein cleavage agent, has a stable structure, good physical and chemical properties, and good pharmacological activities, and is suitable for large scale production to obtain samples with stable, controllable and reliable quality, thereby being suitable for pharmaceutical development.

Abstract: Provided are a compound of formula I which can be used as a drug against small RNA virus infections, and optical isomers, pharmaceutically acceptable salts, solvates or hydrates thereof. Also provided are the preparation method of the compound, the method for using the compound for treating bacterial infections and the use of the compound in the preparation of a drug for preventing and/or treating viral diseases caused by small RNA viruses.

Abstract: The application disclose a method, an apparatus and a system for controlling routing information advertising, which relates to the field of communications and is used for reducing the configuration complexity and reinforcing the operability. The method includes: receiving, by a control device, first routing information sent by a first forwarding device; wherein the first routing information includes an identifier of the first forwarding device; determining a first routing path according to the identifier of the first forwarding device, an identifier of a second forwarding device and a routing path group; and determining an advertising range of second routing information for the second forwarding device according to the first routing path; for enabling the second forwarding device to advertise the second routing information according to the advertising range of the second routing information.

Abstract: Embodiments of the present application disclose a method and an apparatus for determining a next hop and advertising routing information, which relate to the field of communications and are used for reducing operation complexity of a forwarding device and reducing network maintenance workload. The method for determining the next hop provided by the embodiments of the present application includes: receiving, by a control device, first routing information sent by a first forwarding device, where the first routing information includes an identifier of the first forwarding device; determining a first routing path according to the identifier of the first forwarding device, an identifier of a second forwarding device and a routing path group; and determining a next hop in second routing information for the second forwarding device according to the first routing path, where the second forwarding device is a receiver of the second routing information advertised by the control device.

Abstract: The present invention relates to (1S,2S,3S,4R)-3-[(1S)-1-acetylamino-2-ethyl-butyl]-4-guanidino-2-hydroxy-cyclopentyl-1-carboxylic acid hydrates compounds, preparing methods thereof, pharmaceutical compositions containing said compounds and preparing methods thereof, and the clinical uses of said compounds as neuramidinase inhibitors for anti-influenza.

Abstract: A method, a device, and a network system of establishing a tunnel are provided in embodiments of the present disclosure. The method of establishing the tunnel includes: obtaining, by a WTP, an address of an AC and an address of a BRAS from a DHCP server; using, by the WTP, the address of the AC to establish a CAPWAP control tunnel with the AC; and using, by the WTP, the address of the BRAS to establish a CAPWAP data tunnel with the BRAS. By using the technical scheme provided in the embodiments of the present disclosure, the CAPWAP data tunnel may be established between the WTP and the BRAS.

Abstract: A compound of Formula I, or an isomer, pharmaceutically acceptable salt or solvate thereof, is provided. Also, a composition containing a compound of Formula I, or an isomer, pharmaceutically acceptable salt or solvate thereof, and a pharmaceutically acceptable carrier, excipient or diluents, is provided. Further, use of a compound of Formula I, or an isomer, pharmaceutically acceptable salt or solvate thereof for anti-apoptosis is provided, preventing or treating a disease or disorder associated with apoptosis; especially for protecting cardiomyocyte, preventing or treating a disease or disorder associated with cardiomyocyte apoptosis.

Abstract: The present invention relates to a compound of Formula I, or an isomer, pharmaceutically acceptable salt and solvate of the compound, and to a composition comprising the compound of Formula I, or the isomer, pharmaceutically acceptable salt and solvate thereof, and a pharmaceutically acceptable carrier, excipient or diluents. The present invention also relates to use of the compound of Formula I, or the isomer, pharmaceutically acceptable salt and solvate thereof for combating apoptosis, preventing or treating a disease or disorder associated with apoptosis; and especially use for protecting cardiomyocyte, and for preventing or treating a disease or disorder associated with cardiomyocyte apoptosis.