Abstract: The present invention provides a new tea fraction, which is made from the non-ethanol extract, and does not contain caffeine, epigallocatechin gallate (EGCG), gallic acid and catechin that are usually found in conventional tea extracts. The tea fraction has an efficacy in treating a lung fibrosis, particularly idiopathic pulmonary fibrosis (IPF), Covid-19 and long Covid.

Abstract: A fusion protein comprises an Fc variant and a GDF15 active domain, wherein the Fc variant has amino acid substitutions at position 356 and/or position 439 of the IgG Fc according to EU numbering and still has the ability to form homodimer. By fusing the Fc variant with the GDF15 active domain, the Fc-GDF15 fusion protein has significantly improved physicochemical properties and recombinant expression levels, has in vitro activity equivalent to or better than natural GDF15 molecules, and has significantly prolonged in vivo circulating half-life, which can support the dosing frequency of once every two weeks or even once a month.

Abstract: A GDF15 fusion protein and a method for treating obesity using same. The fusion protein includes an Fc variant and a GDF15 active domain, wherein the Fc variant has an amino acid substitution at position 356 and/or position 439 of the IgG Fc according to EU numbering and still has the ability to form a homodimer. By means of fusing the Fc variant with the GDF15 active domain, the Fc-GDF15 fusion protein has significantly improved physical and chemical properties and recombinant expression level, has an in vitro activity comparable to or better than that of a natural GDF15 molecule, and has a significantly prolonged in vivo cyclic half-life, which may support the dosing frequency once every two weeks or even once a month.

Abstract: GDF15 fusion proteins and uses thereof, the fusion protein includes an Fc variant and a GDF15 active domain, wherein the Fc variant has amino acid substitutions at position 356 and/or position 439 of the IgG Fc according to EU numbering and still has the ability to form homodimer. By fusing the Fc variant with the GDF15 active domain, the Fc-GDF15 fusion protein has significantly improved physicochemical properties and recombinant expression levels, has in vitro activity equivalent to or better than natural GDF15 molecules, and has significantly prolonged in vivo circulating half-life, which can support the dosing frequency of once every two weeks or even once a month.

Abstract: The present disclosure relates to display apparatuses and methods for manufacturing the display apparatuses. One example display apparatus includes an array substrate and a laminated structure. The array substrate includes a substrate and an array layer located on a side of the substrate. The laminated structure is located on a side that is of the array layer and that is opposite to the substrate, and includes a first film layer and a second film layer. The first film layer is located on a side that is of the second film layer and that is opposite to the substrate, and is formed by a high modulus material. An elastic modulus of the high modulus material is E1, and 50 Mpa?E1?5 Gpa. The second film layer is formed by a modified energy absorption impact resistance material has viscosity and shear thickening behavior.

Abstract: A touch panel module includes a substrate, a sensor layer disposed on the substrate, a first glue layer disposed on the sensor layer and an anti-electromagnetic interference layer disposed on the first glue layer. The touch panel module with anti-electromagnetic interference can be formed independently, and may be combined with other electronic device to form a touch device, thereby reducing the thickness of the touch device and simplifying the process steps.

Abstract: The present disclosure concerns a digital corneal crosslinking technology for adjusting the corneal curvature, comprising the following steps: administering in drops a composition comprising a photoinitiator compound to the corneal stromal of the subject, locally irradiating the corneal by utilizing digital micromirror device controlled by computer. The corneal curvature can be adjusted totally or locally. The invention also discloses an apparatus for the digital corneal crosslinking. The method and apparatus is minimum invasive and can be used to accurately and efficiently adjust the corneal curvature.

Abstract: A touch panel module includes a substrate, a sensor layer disposed on the substrate, a first glue layer disposed on the sensor layer and an anti-electromagnetic interference layer disposed on the first glue layer. The touch panel module with anti-electromagnetic interference can be formed independently, and may be combined with other electronic device to form a touch device, thereby reducing the thickness of the touch device and simplifying the process steps.

Abstract: The present disclosure provides a touch panel. The touch panel comprises a plurality of first electrode axes, a plurality of second electrode axes, and a plurality of traces. The first electrode axes and the corresponding second electrode axes are disposed at a same level, intertwined, and electrically isolated from each other. The traces connect to the first electrode axes and the second electrode axes from one direction. The present disclosure further provides a manufacturing method of a touch panel. The traces electrically connect to the electrode axes along only one direction, thereby effectively decreasing the area needed to form the traces surrounding the active region and increasing the active region area.

Abstract: The present disclosure concerns a digital fabricating method for constructing 3D structures, comprising the following steps: (a) precursor consist of monomers and photo-initiator is introduced into reaction cell; (b) exposing the precursor to the DLP projector for several times to gain an inhomogeneous sheet; (c) swelling the sheet in solvent to gain 3D structure. The disclosure provides a simple and easy way to produce precise 3D structure.

Abstract: A touch panel includes a protective cover with a lower surface herein, and an active region and a periphery region defined on the lower surface. A first sensing structure is disposed on the lower surface and covers the active region. A shelter layer is disposed on the lower surface and in the periphery region, wherein the shelter layer includes a highlight region and a highlight contrast region, a first pattern is disposed in the highlight region, and a non-transparent layer with a second pattern is disposed in the highlight region, wherein the first pattern is overlapped by the second pattern.

Abstract: The present disclosure concerns a digital corneal crosslinking technology for adjusting the corneal curvature, comprising the following steps: administering in drops a composition comprising a photoinitiator compound to the corneal stromal of the subject, locally irradiating the corneal by utilizing digital micromirror device controlled by computer. The corneal curvature can be adjusted totally or locally. The invention also discloses an apparatus for the digital corneal crosslinking. The method and apparatus is minimum invasive and can be used to accurately and efficiently adjust the corneal curvature.

Abstract: The present disclosure concerns a digital fabricating method for constructing 3D structures, comprising the following steps: (a) precursor consist of monomers and photo-initiator is introduced into reaction cell; (b) exposing the precursor to the DLP projector for several times to gain an inhomogeneous sheet; (c) swelling the sheet in solvent to gain 3D structure. The disclosure provides a simple and easy way to produce precise 3D structure.

Abstract: A touch panel includes a protective cover with a lower surface herein, and an active region and a periphery region defined on the lower surface. A first sensing structure is disposed on the lower surface and covers the active region. A shelter layer is disposed on the lower surface and in the periphery region, wherein the>shelter layer includes a highlight region and a highlight contrast region, a first pattern is disposed in the highlight region, and a non-transparent layer with a second pattern is disposed in the highlight region, wherein the first pattern is overlapped by the second pattern.

Abstract: A touch panel includes a protective cover with a lower surface herein, and an active region and a periphery region defined on the lower surface. A first sensing structure is disposed on the lower surface and covers the active region. A shelter layer is disposed on the lower surface and in the periphery region, wherein the shelter layer includes a highlight region and a highlight contrast region, a first pattern is disposed in the highlight region, and a non-transparent layer with a second pattern is disposed in the highlight region, wherein the first pattern is overlapped by the second pattern.

Abstract: A touch panel comprises a transparent substrate and a non-transparent insulation layer disposed on the transparent substrate. The non-transparent insulation layer has a first opening, and a second opening corresponding to a graphic region. The touch panel further comprises transparent conductive patterns disposed in the first opening and the second opening, and non-transparent conductive patterns disposed on the non-transparent insulation layer outside of the graphic region. The non-transparent conductive patterns electrically connect the transparent conductive pattern in the second opening.

Abstract: The present disclosure relates to a touch technology, and more particularly, to a touch panel and a manufacturing method thereof. The present invention discloses a touch panel comprising a touch region, a first peripheral region at the first side of said touch region, a second peripheral region at the second side opposite to said first side, a plurality of first axial electrodes and second axial electrodes that intersect with each other diagonally to limit peripheral routing in the two peripheral regions, a plurality of peripheral first lead-wires disposed at the first peripheral region, and a plurality of second lead wares disposed at the second peripheral region. A manufacturing method of a touch panel is also provided.

Abstract: The present disclosure relates to a touch sensing device comprising a plurality of sensing electrode units and an insulating pattern layer. The insulating pattern layer covers the plurality of sensing electrode units and has a plurality of openings that are not corresponding to plurality of sensing electrode units. The present disclosure also discloses a method for manufacturing the touch sensing device.

Abstract: A touch panel includes a protective cover with a lower surface herein, and an active region and a periphery region defined on the lower surface. A first sensing structure is disposed on the lower surface and covers the active region. A shelter layer is disposed on the lower surface and in the periphery region, wherein the shelter layer includes a highlight region and a highlight contrast region, a first pattern is disposed in the highlight region, and a non-transparent layer with a second pattern is disposed in the highlight region, wherein the first pattern is overlapped by the second pattern.

Abstract: The present disclosure provides a touch panel. The touch panel comprises a plurality of first electrode axes, a plurality of second electrode axes, and a plurality of traces. The first electrode axes and the corresponding second electrode axes are disposed at a same level, intertwined, and electrically isolated from each other. The traces connect to the first electrode axes and the second electrode axes from one direction. The present disclosure further provides a manufacturing method of a touch panel. The traces electrically connect to the electrode axes along only one direction, thereby effectively decreasing the area needed to form the traces surrounding the active region and increasing the active region area.