Patents by Inventor Limei Ma

Limei Ma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Branchiostoma derived fluorescent proteins
    Patent number: 9102750
    Abstract: The present invention provides compositions, combinations, methods, sequences and kits for use of novel fluorescent proteins derived from the genus Branchiostoma. Specifically, polynucleotide and polypeptide sequences encoding fluorescent proteins isolated from Branchiostoma floridae, including harmonized sequences, which permit enhanced expression of the encoded polypeptides in mammalian cells in vivo are provided.
    Type: Grant
    Filed: February 4, 2014
    Date of Patent: August 11, 2015
    Assignee: Stowers Institute for Medical Research
    Inventors: Arcady Mushegian, Congrong Yu, Joel Schwartz, Limei Ma
  • Fluorescent mouse model
    Patent number: 9018440
    Abstract: The present invention relates to compositions and methods useful for detecting and/or measuring, e.g., intracellular signaling in vivo. More particularly, compositions and methods are provided, which include transgenic animals, that are useful in mapping and examining, e.g., calcium fluctuations in vivo between and within populations of cells in real time. Methods for screening for candidate compounds that effect, e.g., intracellular calcium signaling are also provided.
    Type: Grant
    Filed: October 24, 2007
    Date of Patent: April 28, 2015
    Assignee: Stowers Institute for Medical Research
    Inventors: Congrong (Ron) Yu, Limei Ma
  • NOVEL BRANCHIOSTOMA DERIVED FLUORESCENT PROTEINS
    Publication number: 20140220629
    Abstract: The present invention provides compositions, combinations, methods, sequences and kits for use of novel fluorescent proteins derived from the genus Branchiostoma. Specifically, polynucleotide and polypeptide sequences encoding fluorescent proteins isolated from Branchiostoma floridae, including harmonized sequences, which permit enhanced expression of the encoded polypeptides in mammalian cells in vivo are provided.
    Type: Application
    Filed: February 4, 2014
    Publication date: August 7, 2014
    Applicant: STOWERS INSTITUTE FOR MEDICAL RESEARCH
    Inventors: Arcady MUSHEGIAN, Congrong (Ron) YU, Joel SCHWARTZ, Limei MA
  • Branchiostoma derived fluorescent proteins
    Patent number: 8680235
    Abstract: The present invention provides compositions, combinations, methods, sequences and kits for use of novel fluorescent proteins derived from the genus Branchiostoma. Specifically, polynucleotide and polypeptide sequences encoding fluorescent proteins isolated from Branchiostoma floridae, including harmonized sequences, which permit enhanced expression of the encoded polypeptides in mammalian cells in vivo are provided.
    Type: Grant
    Filed: September 24, 2007
    Date of Patent: March 25, 2014
    Assignee: Stowers Institute For Medical Research
    Inventors: Arcady Mushegian, Congrong (Ron) Yu, Joel Schwartz, Limei Ma, Malcolm Cook
  • Novel Branchiostoma Derived Fluorescent Proteins
    Publication number: 20100168396
    Abstract: The present invention provides compositions, combinations, methods, sequences and kits for use of novel fluorescent proteins derived from the genus Branchiostoma. Specifically, polynucleotide and polypeptide sequences encoding fluorescent proteins isolated from Branchiostoma floridae, including harmonized sequences, which permit enhanced expression of the encoded polypeptides in mammalian cells in vivo are provided.
    Type: Application
    Filed: September 24, 2007
    Publication date: July 1, 2010
    Inventors: Arcady Mushegian, Congrong (Ron) Yu, Joel Schwartz, Limei Ma, Malcolm Cook
  • FLUORESCENT MOUSE MODEL
    Publication number: 20100154068
    Abstract: The present invention relates to compositions and methods useful for detecting and/or measuring, e.g., intracellular signaling in vivo. More particularly, compositions and methods are provided, which include transgenic animals, that are useful in mapping and examining, e.g., calcium fluctuations in vivo between and within populations of cells in real time. Methods for screening for candidate compounds that effect, e.g., intracellular calcium signaling are also provided.
    Type: Application
    Filed: October 24, 2007
    Publication date: June 17, 2010
    Inventors: Congrong (Ron) Yu, Limei Ma