Abstract: The present application relates to azaaromatic amide derivatives for the treatment of cancer. Specifically, the present application relates to a preparation method and use of azaaromatic amide derivatives. The present application relates to azaaromatic amide derivatives and anilino-pyrimidine compounds represented by formula (I), formula (II), formula (III), formula (IV), and formula (V), and pharmaceutically acceptable salts thereof; the compounds or salts thereof can be used to treat or prevent a disease or disorder by regulating certain mutant forms of epidermal growth factor receptors. The present application also relates to a pharmaceutical composition comprising the compounds or salts thereof, and a method for treating various diseases mediated by EGFR, or HER2, or HER4 by using the compounds and salts thereof.

Abstract: A current collector disk and a battery. The current collector disk includes a disk body on which a plurality of infiltration holes is provided. The infiltration holes penetrate through the disk body in a direction of a thickness of the disk body. The disk body has a first side surface and a second side surface which are oppositely disposed. The first side surface is recessed with a plurality of grooves. At least one end of each of the plurality of grooves communicates with a respective one of the plurality of infiltration holes. The battery includes the current collector disk described above.

Abstract: A method for prefabricating pore defects by controlling a SLM process, including performing laser scanning on a specified metal melt layer (LY) according to a first scan path (P1) and a second scan path. The first scan path (P1) and the second scan path (P2) have a path overlap zone (A0), the path overlap zone (A0) has a predetermined width, and laser energy input superimposed in the path overlap zone (A0) is controlled to reach a predetermined energy value, whereby keyholes are formed at a plurality of positions in a lengthwise direction of the path overlap zone (A0), the specified metal melt layer (LY) is taken as a defect layer, and the keyholes in the path overlap zone (A0) is taken as pore defects.

Abstract: Disclosed are a molecular imaging method using Raman spectra and system based on machine learning cascade. The system includes a coordinate localization module, a hierarchical clustering analysis module, a Raman predictive imaging module, and a similarity analysis module. An untreated frozen tissue slice is attached to a stainless steel slide, and an adjacent slice is attached to a glass slide. The coordinate localization module can match a Raman white light image of a detection sample attached to the stainless steel slide with an immunohistochemistry (IHC) image of the adjacent slice, such that Raman spectra of a target region are accurately collected. The hierarchical clustering analysis module purifies different types of Raman spectra. A machine learning classifier is configured to build a Raman predictive imaging model. The similarity analysis module can evaluate similarity between a predicted Raman predictive image and the IHC image of the adjacent slice.

Abstract: A vacuum chamber structure of an ultra-high gravity geotechnical centrifuge device, comprising: a cylindrical shell, a convex head, a bottom head, a lower bearing sealing cover, and a vacuum pressure-bearing chamber formed by sealing a top cylindrical cylinder and an upper sealing plate with sealing rings; wherein a high-speed rotor system is enclosed in the vacuum pressure-bearing chamber, and a cylindrical cooling device is installed between an internal side of the cylindrical shell and the high-speed rotor system. An annular cooling device is provided directly above the hanging baskets on both sides of the centrifuge arm. A vibration isolation expansion joint is arranged at the intersection of the high-speed rotor system and the cylindrical cylinder, which isolates the vibration of the main engine from the vacuum chamber and greatly reduces the vibration.

Abstract: An inspection system and method, the inspection system includes: a carrying device, at least one ray source and a detector assembly. The ray source and the detector assembly are lifted or lowered along a central axis of the carrying device relative to the carrying device. When viewed along the central axis, the ray source is translatable between scanning positions relative to the carrying device. When the ray source is at one of the scanning positions the ray source and the detector assembly are lifted or lowered relative to the carrying device along the central axis, and the ray source emits X-rays; and when the ray source and the detector assembly are lifted or lowered a predetermined distance the ray source translates to another scanning position. The inspection system further reconstructs a three-dimensional scanning image of the object to be inspected based on detection data of the detector assembly.

Abstract: Disclosed are smart glasses and a manufacturing method therefor. The smart glasses comprise a first assembly comprising a front crossbeam portion, a camera assembly and an optical mechanical assembly; and a second assembly comprising a rear crossbeam portion, a first temple and a second temple, wherein the first assembly is inserted into the second assembly. The first temple is provided with a first cavity; and the second temple is provided with a second cavity. A hollow passage for communicating the first cavity with the second cavity is enclosed by the front crossbeam portion and the rear crossbeam portion, the camera assembly is at least partially arranged in the first cavity, and the optical-mechanical assembly is at least partially arranged in the second cavity. The disclosed smart glasses have improved performance with enhanced convenience of assembly and ease of operation.

Abstract: In a method for displaying virtual characters in a virtual scene, the virtual scene is displayed in a first application on a first terminal. A first account corresponding to a first virtual character is logged into the first application. An interaction control element is displayed in the virtual scene. The interaction control element indicates interaction information between the first account and a second account in an interaction scene outside the virtual scene. In response to detecting a user operation on the interaction control element, a second virtual character corresponding to the second account is added to the virtual scene. Apparatus and non-transitory computer-readable storage medium counterpart embodiments are also contemplated.

Abstract: A fluorocarbon/palladium/magnesium-scandium hydrogen-chromic film and a preparation method thereof are provided. The film includes a magnesium-scandium composite film layer, a palladium catalytic layer, and a fluorocarbon film layer that are sequentially arranged on a substrate. The preparation method includes: growing the magnesium-scandium composite film layer on the substrate first, then growing the palladium catalytic layer in situ on the magnesium-scandium layer, and finally depositing the fluorocarbon film layer on Pd. According to the present invention, the catalytic effect of palladium is utilized to promote reversible conversion between hydrogen and hydrogen atoms during hydrogen absorption and dehydrogenation stages, and a composite scandium element is added to accelerate diffusion of the hydrogen atoms in a magnesium matrix and accelerate formation and decomposition of a hydride, such that the film can be repeatedly and rapidly switched between a reflective state and a transparent state.

Abstract: An image sensor comprises an arrangement of pixels, the pixels including an acquisition circuit each, the acquisition circuit including: a sensor circuit configured to generate a sensor signal (VLOG) depending on a light signal illuminating a photosensor of the pixel; a storage circuit configured to store during a storage interval a stored signal (VSTORE) proportional to the sensor signal (VLOG); and a comparator circuit configured to generate after the refresh interval a comparator signal (VCOMP) depending on the sensor signal (VLOG) and the stored signal (VSTORE). A method of operating an image sensor comprises steps of generating a sensor signal (VLOG) depending on a light signal illuminating a photosensor of the pixel, storing during a storage interval a stored signal (VSTORE) proportional to the sensor signal (VLOG) and generating after the refresh interval a comparator signal (VCOMP) depending on the sensor signal (VLOG) and the stored signal (VSTORE).

Abstract: Systems and methods of large depth-of-field microscopic structured-light 3D imaging include and/or implement capturing a plurality of images of a scene using a plurality of focus settings, each of the plurality of images corresponding to one of the plurality of focus settings, the plurality of images corresponding to a focal stack; processing the plurality of images; merging the plurality of images into an all-in-focus phase map; and reconstructing a 3D shape of the scene based on the all-in-focus phase map.

Abstract: A test device for rigid-flexible characteristics of a rigid-flexible transition overhead conductor rail, includes a movable vehicle moved in a length extending direction of the overhead conductor rail. A telescopic mechanism for providing lifting force for the overhead conductor rail is mounted on the movable vehicle and stretches out and draws back in a vertical direction, and a conversion plate is connected to a top end of the telescopic mechanism and synchronously moved in the vertical direction therewith. A sliding assembly is mounted at a top of the conversion plate and slides along the overhead conductor rail with the movable vehicle. The overhead conductor rail is located over the sliding assembly which abuts against a bottom wall of the overhead conductor rail. A force sensor is arranged between the telescopic mechanism and the conversion plate. A displacement detection mechanism is arranged on the conversion plate.

Abstract: An intrusion response system (IRS) can include a knowledge-based intrusion response (IR) component configured to use knowledge of prior responses to prior behavior of at least one computer system to determine a first response to behavior of a target computer system; a prediction-based IR component configured to use at least one trained machine learning (ML) model of behavior of the target computer system to predict a second response to the behavior of the target computer system; and a response component configured to determine an output response to the behavior of the target computer system based on at least one of the first response and the second response.

Abstract: A collaboration platform provides a collaboration user interface (“UI”) through which a user can request a recommendation of an artificial intelligence (“AI”) model for performing entity extraction on documents in a document library maintained by the collaboration platform. In response to receiving such a request, the collaboration platform can select candidate documents from the documents in the library and process the candidate documents using AI models configured to extract entities from the one or more documents. The collaboration platform can then select one of the AI models based on the processing. The collaboration platform can also provide functionality for performing automated document tagging using term sets on documents maintained by the collaboration platform.

Abstract: The present disclosure relates to a deep learning algorithm compiling method and a device and a related product, the product comprising a controller unit, and the controller unit comprising: an instruction cache unit, an instruction processing unit, and a queue-storing unit. The instruction cache unit is configured to store computation instructions associated with artificial neural network operations. The instruction processing unit is configured to parse the computation instructions to obtain a plurality of operation instructions. The queue-storing unit is configured to store an instruction queue, which comprises: a plurality of operation instructions or computation instructions to be executed according to the front-to-rear sequence of the queue. By means of the described method, the present disclosure may improve the operation efficiency of the related product when carrying out neural network model operations.

Abstract: This invention discloses a model test device and method for curtain grouting and excavation of tunnels in high-temperature, water-rich and weak strata, comprising weak strata simulation system, working condition simulation system, curtain grouting system, and monitoring and data acquisition system. The weak strata simulation system is the main box used to fill the soft soil. The working condition simulation system includes a high geothermal simulation system, a water pressure simulation system with stepwise loading of water pressure and volume, and a three-dimensional confining pressure simulation system with stepwise controllable loading of confining pressure. The invention can realize the whole test process simulation of grouting reinforcement and excavation of tunnels in weak strata effectively under the action of confining pressure and geothermal heat, and it has a positive reference effect on actual soft stratum tunnel curtain grouting and safe excavation.