Abstract: A medical article having neutralized sulfonic acid groups on its surface, is disclosed. The article has reduced interaction with biological fluids such as insulin, human growth hormone and human serum albumin.

Abstract: Measurements made with a multicomponent logging instrument when used in a substantially horizontal borehole in earth formations provide diagnostic of the direction of beds relative to the position of the borehole. When the logging instrument is conveyed on a drilling assembly, the drilling trajectory may be maintained to follow a predetermined trajectory or to maintain a desired distance from a boundary such as an oil-water contact.

Abstract: Disclosed herein is a plasmonics platform comprising a substrate; a plurality of periodically spaced nanoholes and/or nanoparticles disposed upon the substrate; wherein the average first order of periodicity between the nanoholes and/or the nanoparticles is about 5 to about 1,000 nm; and a microelectromechanical and/or a nanoelectromechanical system in operative communication with the substrate so as to vary the average first order of periodicity between the nanoholes and/or the nanoparticles.

Abstract: Provided herein are techniques for screening materials for hemocompatibility. Hemocompatible materials may be advantageous when incorporated into devices that may come into direct contact with blood or other bodily fluids. Such techniques take advantage of conformational changes in fibrinogen when adsorbed onto certain materials. As a result of conformational changes, the fibrinogen has altered responsiveness to cleavage by thrombin. Accordingly, the products of thrombin cleavage of fibrinogen may be assessed to determine the hemocompatibility of a material.

Abstract: Neural networks may be used to determine and predict formation dip angles and perform quality assurance assessments from data collected with a multi-component induction tool used for well logging. The neural networks make use of corrected, rotated and normalized data to provide the predictions and assessments. Synthetic data using various models is used to train the neural networks. The teachings herein provide for real-time determinations with a substantial degree of accuracy in the results.

Abstract: Cross-component measurements made with a dual-transmitter configuration are processed to estimate a distance to an interface in an anisotropic earth formation. Optionally, measurements may be made with two receivers, also in the dual transmitter configuration.

Abstract: The present invention provides a fluorogenic composition for assaying complement activation that comprises a substrate for C3 convertase that is linked to a first fluorophore and a second fluorophore, wherein the fluorescence of the first and second fluorophores are mutually substantially quenched when the two fluorophores are present at a distance less than the characteristic distance for the two fluorophores. In one embodiment, the fluorescence of the first fluorophore is substantially quenched by the second fluorophore, and the second fluorophore emits heat upon quenching. The present invention also provides a method for assaying complement activation, wherein the method includes the steps of incubating a biological sample with a polymer to provide a polymeric biological sample, followed by incubating the polymeric biological sample with the fluorogenic composition, and measuring the fluorescence.

Abstract: Measurements made with a multicomponent logging instrument when used in a substantially horizontal borehole in earth formations are diagnostic of the direction of beds relative to the position of the borehole. When the logging instrument is conveyed on a drilling assembly, the drilling trajectory may be maintained to follow a predetermined trajectory or to maintain a desired distance from a boundary such as an oil-water contact.

Abstract: Disclosed herein is a plasmonics platform comprising a substrate; a plurality of periodically spaced nanoholes and/or nanoparticles disposed upon the substrate; wherein the average first order of periodicity between the nanoholes and/or the nanoparticles is about 5 to about 1,000 nm; and a microelectromechanical and/or a nanoelectromechanical system in operative communication with the substrate so as to vary the average first order of periodicity between the nanoholes and/or the nanoparticles.

Abstract: Multi-component induction measurements are made using a resistivity logging tool in an anistropic earth formation. A subset of the multi-component measurements are inverted to first determine horizontal resistivities. Using the determined horizontal resistivities and another subset of the multi-component measurements, the vertical resistivities are obtained. Results of using the in-phase signals are comparable to those obtained using multifrequency focusing of quadrature signals.

Abstract: Multi-component induction measurements are made using a resistivity logging tool in an anistropic earth formation. A subset of the multi-component measurements are inverted to first determine horizontal resistivities. Using the determined horizontal resistivities and another subset of the multi-component measurements, the vertical resistivities are obtained. Results of using the in-phase signals are comparable to those obtained using multifrequency focusing of quadrature signals.

Abstract: An improved induction tool for formation resistivity evaluations. The tool provides electromagnetic transmitters and sensors suitable for transmitting and receiving magnetic fields in radial directions that are orthogonal to the tool's longitudinal axis with minimal susceptibility to errors associated with parasitic eddy currents induced in the metal components surrounding the transmitter and receiver coils. Various transmitter receiver combinations are provided to select sensitivity to a desired reservoir formation properties, for example, different orientations xy, xz, yz, 20-40, 20-90, and combinations, such as, Symmetric-symmetric; Asymmetric-symmetric; and Asymmetric-asymmetric. Measurements made with a multi-component logging instrument when used in a substantially horizontal, vertical or deviated borehole in earth formations are diagnostic of the direction of resistive beds relative to the position of the borehole.

Abstract: Measurements made with a multicomponent logging instrument when used in a substantially horizontal borehole in earth formations are diagnostic of the direction of beds relative to the position of the borehole. When the logging instrument is conveyed on a drilling assembly, the drilling trajectory may be maintained to follow a predetermined trajectory or to maintain a desired distance from a boundary such as an oil-water contact. It is emphasized that this abstract is provided to comply with the rules requiring an abstract which will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims. 37 CFR 1.

Abstract: Provided herein are compositions and methods for lipoprotein uptake assay. These compositions and methods may be used for the lipoprotein uptake assays, including high-throughput assays. The disclosed compositions and method may further be used to characterize the activity agents that inhibit or stimulate lipoprotein uptake.

Abstract: An improved induction tool for formation resistivity evaluations. The tool provides electromagnetic transmitters and sensors suitable for transmitting and receiving magnetic fields in radial directions that are orthogonal to the tool's longitudinal axis with minimal susceptibility to errors associated with parasitic eddy currents induced in the metal components surrounding the transmitter and receiver coils. Various transmitter receiver combinations are provided to select sensitivity to a desired reservoir formation properties, for example, different orientations xy, xz, yz, 20-40, 20-90, and combinations, such as, Symmetric-symmetric; Asymmetric-symmetric; and Asymmetric-asymmetric. Measurements made with a multi-component logging instrument when used in a substantially horizontal, vertical or deviated borehole in earth formations are diagnostic of the direction of resistive beds relative to the position of the borehole.

Abstract: Neural networks may be used to determine and predict formation dip angles and perform quality assurance assessments from data collected with a multi-component induction tool used for well logging. The neural networks make use of corrected, rotated and normalized data to provide the predictions and assessments. Synthetic data using various models is used to train the neural networks. The teachings herein provide for real-time determinations with a substantial degree of accuracy in the results.

Abstract: Provided herein are compositions and methods for lipoprotein uptake assay. These compositions and methods may be used for the lipoprotein uptake assays, including high-throughput assays. The disclosed compositions and method may further be used to characterize the activity agents that inhibit or stimulate lipoprotein uptake.

Abstract: The present invention provides compositions and methods for preparation of a three-dimensional transendothelial cell migration (TEM) assay. These compositions and methods are uniquely suited for the high throughput TEM assay, and for the analysis and identification of TEM mediators which inhibit or stimulate this process. The composition for detecting migration of cells comprises a solid layer comprising collagen gel; a first cellular layer in contact with the solid layer and comprising a first cell type; and a second cell type seeded on top of the first cellular layer. Optionally, gelatin is included in the collagen gel. A 96 well plate format is disclosed, the combination with a high throughput cellular scanner enables high throughput TEM assay.

Abstract: A siren housing has a dish-shaped base having a back wall adapted to be secured to as support structure. The base is configured and dimensioned to contain siren components. A post projects forwardly from the back wall. The post has a cylindrical sidewall terminating at a front rim. At least one channel circumscribes a segment of the sidewall at a location spaced rearwardly from the front rim. Entry and exit slots communicate with the channel at spaced locations along the length thereof. The entry slot leads to the front rim and the exit slot leading towards the back wall. A dish-shaped cover has a front wall. A cylindrical sleeve projects rearwardly from the front wall, the sleeve having at least one pin projecting radially inwardly therefrom. The sleeve is dimensioned for axial insertion onto the post.