Abstract: A microwell array chip, a use method therefor, and a detection apparatus. The microwell array chip includes a microwell array substrate, and the microwell array substrate includes n reaction chambers, and an idle region; an array of the n reaction chambers is disposed in the microwell array substrate, and the idle region is disposed around the n reaction chambers; each reaction chamber is configured to accommodate a sample to be tested, and the shape of an orthographic projection of the reaction chamber on a first reference plane where the first main surface is located is of a regular N-gon; the area of the idle region is divided into n? virtual units, and the shape of the orthographic projection of each virtual unit on the first reference plane is the same as the shape of the orthographic projection of the reaction chamber on the first reference plane.

Abstract: Disclosed are compounds of formula I: in which all the variables are defined. Also disclosed are ligand-PD conjugates formed of a compound of formula I, a method of treating cancer using such a conjugate, and a pharmaceutical composition containing the conjugate.

Abstract: An electronic device includes a first electronic unit emitting a first light and a second electronic unit emitting a second light. The first light is a blue light and has a first spectrum having a first intensity, and the first intensity is a maximum intensity of the first spectrum. The second light has a second spectrum, wherein the first light and the second light have different colors. The second spectrum has a second intensity, and the second intensity is a maximum intensity of the second spectrum. The first intensity is greater than the second intensity.

Abstract: A semiconductor device is provided, which includes an active structure, a first semiconductor layer, a second semiconductor layer, an insulating layer, and a conductive layer. The active region has two sides and includes an active region. The first semiconductor layer and the second semiconductor layer respectively located on the two sides of the active structure. The insulating layer covers a portion of the first semiconductor layer. The conductive layer covers the insulating layer and physically contacts the first semiconductor layer. The second semiconductor layer includes a first dopant and the first semiconductor layer includes a second dopant different from the first dopant. The first semiconductor layer includes a quaternary III-V semiconductor material, and the active region includes a quaternary semiconductor material, and the semiconductor device emits a radiation having a peak wavelength between 800 nm and 2000 nm.

Abstract: A drug conjugate includes a structure shown by the following formula: Z-(linker-[R]m)n. In the formula, Z is a drug compound, R is a sugar, and m and n are independently an integer from 1 to 6. The drug compound Z is a hepatitis virus targeting drug, a hepatitis B virus (HBV) drug, an inhibitor of apoptosis protein (IAP) antagonist, a multidrug resistance (MDR) inhibitor, or analogues, precursors, prodrugs, derivatives thereof.

Abstract: Provided is a window cleaning machine including a body, air extracting module, first cleaning device, second cleaning device, walking module disposed near the body, and driving device connected to the first and second cleaning devices to cause a reciprocating motion thereof. The body defines a primary suction space. The air extracting module is disposed on the body and is in communication with the primary suction space. The first and second cleaning devices are each in contact with a pane surface while performing a cleaning operation. The first cleaning device defines a first subsidiary space in communication with the primary suction space. The second cleaning device defines a second subsidiary space in communication with the primary suction space. The walking module is disposed outside the first and second subsidiary spaces. The window cleaning machine undergoes the reciprocating motion across a non-horizontal pane surface while clinging firmly thereto by suction.

Abstract: A peritoneal dialysis (“PD”) system includes a cycler including an actuation surface having a peristaltic pump actuator; a manifold assembly including a rigid manifold having first and second chambers, the rigid manifold configured and arranged to be abutted against the actuation surface for operation, a peristaltic pump tube extending from the first chamber to the second chamber of the rigid manifold, a dialysis fluid container line extending from the first chamber, and a branch line extending between the dialysis fluid container line and the second chamber; and a control unit configured to cause the peristaltic pump actuator to actuate the peristaltic pump tube to pump dialysis fluid from the branch line into the second chamber and from the second chamber into the first chamber.

Abstract: A window cleaning machine includes a body, walking module, air extracting module, first cleaning device and driving device. The body defines a primary suction space. The walking module is disposed near the body. The air extracting module is disposed on the body and is in communication with the primary suction space, allowing the body to cling to the pane surface by suction. The first cleaning device is in contact with the pane surface while performing a cleaning operation. The driving device is connected to the first cleaning device to cause the first cleaning device to undergo a reciprocating motion so as to wipe the pane surface back and forth. The body further comprises a bottom board and a carrying board. The bottom board comprises a bottom board wall portion enclosing a first bottom board through hole. The carrying board is disposed between the first cleaning device and the bottom board.

Abstract: A window cleaning machine provided according to an embodiment of the disclosure comprises a resilient member disposed between a body and a first cleaning device to prevent external air from passing between the body and the first cleaning device and entering a primary suction space of the body.

Abstract: A cleaning system and a cleaning method are provided. The cleaning system includes a main body, an air suctioning device, a light source, an optical sensor, a memory and a processing unit. The air suctioning device includes an air flow passage and a fan-motor assembly that is disposed in the air flow passage and generates a suction force to suction outside air through the air flow passage. The light source emit light to the air flow passage. The optical sensor captures a plurality of successive image frames from the air flow passage. The processing unit is configured to: obtain first and second image frames from the successive image frames; compare the first image frame with the second image frame to identify dust particles; obtain a particle feature of the dust particles; and determine a current cleanness condition according to the particle feature.

Abstract: The invention refers to an apparatus (120) for accessing hair characteristic while brushing hair of a subject, wherein the apparatus comprises a vibration measurement providing unit (121) for providing a vibration signal indicative of a result of a vibration measurement performed by one or more vibration sensors (112) integrated into a hairbrush (110) comprising a plurality of bristles (111). The vibration measurements are performed by the vibration sensors during a brushing of the hair using the hairbrush and are indicative of vibrations of the bristles of the hairbrush during the brushing. A hair characteristic determination unit (122) then determines a hair characteristic based on the vibration signal.

Abstract: A brush wetting and cleaning system or tool including a brush wetting and cleaning housing. A wetting nozzle in fluid communication with a cavity in the brush wetting and cleaning housing. The wetting nozzle is configured to, in operation, wet a brush of a brush head inserted into the cavity of the brush wetting and cleaning housing. A spray nozzle in fluid communication with the cavity in the brush wetting and cleaning housing. The spray nozzle is configured to, in operation, clean the brush of the brush head inserted into the cavity of the brush wetting and cleaning housing. In a method of utilizing the brush wetting and cleaning system or tool, the brush of the brush head is wetted and cleaned between cleaning successive wafers or workpieces.

Abstract: A novel type of cationic lipid and PEGylated derivative thereof, a cationic liposome and a cationic liposome-nucleic acid pharmaceutical composition containing the cationic lipid and formulation thereof include an ionizable lipid compound of the general formula (1). This compound is slightly ionized or neutral at physiological pH but undergoes greater ionization under acidic conditions, exhibiting lower toxicity in the systemic circulation and improved endosomal escape ability. The compound's polar head contains an ionizable tertiary amine group along with a side chain containing functional groups, while the tail chains may include linking groups that are easily degraded. Cationic liposomes containing the compound have a better ability to complex with nucleic acid drugs, higher stability in serum, no apparent cytotoxicity, and high transfection efficiency.

Abstract: The present invention provides compositions and methods for treating a disease treatable by asparagine depletion in a human subject comprising administering to a human subject a recombinant L-asparaginase.

Abstract: The present disclosure provides a copper-magnesium co-doped carbonized wood sponge material, a preparation therefor, and an application thereof, and a method for converting plastics into fuel based on a Fenton-like system. In the present disclosure, a copper-magnesium co-doped carbonized wood sponge catalyst is prepared by high-temperature pyrolysis after a wood raw material is coated with polydopamine (PDA) and a copper element and a magnesium element are loaded on a wood sponge substrate, realizing the loading of a nanoreactor on a wood sponge layered structure, and forming a unique spatial microenvironment and synergistic effect by combining a superior three-dimensional lamellar structure of the wood sponge substrate with the structural advantages of the nanoreactor to promote an electron transfer pathway on a surface.

Abstract: Provided is an immunogenic composition including a peptide, wherein consecutive amino acids of the peptide include at least amino acids of SEQ ID NO:1 and one or more adjuvant.

Abstract: An electronic device manufacturing system configured to obtain current sensor data associated with a sensor of a substrate manufacturing system and determine a slope value associated with the current sensor data. Responsive to determining that the slope value satisfied a threshold criterion associated with a fault detection limit, at least one of an alert is generated or a corrective action performed.

Abstract: A semiconductor structure including a substrate, a capacitor, and an oxide semiconductor field effect transistor (OSFET). The capacitor is located on the substrate. The oxide semiconductor field effect transistor is located on the substrate. The oxide semiconductor field effect transistor is electrically connected to the capacitor.

Abstract: The present invention disclosed a 1,4-diheterocyclic substituted aromatic ring or aromatic heterocyclic compound represented by formula (I). The compound can effectively inhibit the generation of 20-HETE, and has high activity, high selectivity and good pharmacokinetic characteristics. By means of the inhibition on the generation of 20-HETE, the compound can be used for treating various diseases related to 20-HETE, and thus has a great application value.

Abstract: Disclosed is a skin care composition comprising porous silica, silicone elastomer, and triglyceride for solving the pilling problem.