Abstract: The present invention provides a whole new method for creating high density microarrays by operating inkjet printing technology, comprising the steps of: (1) mixing solution comprising biomaterial and solvent as aqueous-based inkjet ink stock; (2) revising the control software program of inkjet printing for homologizing spreading dots and shapeliness; (3) using solid support material wherein coated with high density brushes of poly-urethane for absorption of biomaterial with low background by scanner; (4) printing said dot units contain mixing solution on solid support material; and (5) screening to identify all dot units on microarray contain biomaterial by scanner. This invention provides an user friendliness, accuracy, cost-effectiveness and improved version of simplified microarrays technology.

Abstract: A method for regulating the skin and hair color in a post-natal mammalian by preparing a recombinant vector in which an agouti-encoding DNA segment is positioned under the control of a promoter and introducing the recombinant vector into skin cells of the mammalian. The recombinant vector carrying the genes expresses related proteins after they are introduced to most mammalian cells.