Patents by Inventor Lin Ji

Lin Ji has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11278592
    Abstract: A method of treating a subject having a cancer comprising administering a tumor suppressor therapy, such as a TUSC2 therapy, in conjunction with an immune checkpoint inhibitor. Kits and reagents for use in cancer therapy are also provided.
    Type: Grant
    Filed: October 12, 2017
    Date of Patent: March 22, 2022
    Assignee: Board of Regents, The University of Texas System
    Inventors: Jack A. Roth, Lin Ji
  • Publication number: 20210048658
    Abstract: A two-photon stimulated emission depletion composite microscope, comprising a two-photon imaging unit (100) and an STED imaging unit (200), wherein the two-photon imaging unit (100) can be used for a relatively thick sample, and the STED super-resolution imaging unit can be used for a region of interest on a surface of a sample, and the microscope makes light spots generated by an excitation light and a depletion light after being focused by an objective lens (OL) accurately coincide in a three-dimensional distribution. The two-photon stimulated emission depletion composite microscope (10) integrates two functions of STED imaging and two-photon imaging and makes the two types of light spots generated by an excitation light and a depletion light after being focused by an objective lens accurately coincide in a three-dimensional distribution, thereby providing a powerful tool for cutting-edge biomedical research.
    Type: Application
    Filed: November 27, 2018
    Publication date: February 18, 2021
    Inventors: Yuguo Tang, Yunhai Zhang, Tongda Wei, Jian Chang, Haomin Yang, Lin Ji
  • Publication number: 20210041363
    Abstract: A two-photon stimulated emission depletion composite microscope using continuous light loss, the microscope comprising: a two-photon imaging unit (100) and an STED imaging unit (200), wherein for thicker samples, the two-photon imaging unit (100) can be used, and for regions of interest on the surface of samples, the STED super-resolution imaging unit (200) can be used. The two-photon stimulated emission depletion composite microscope using continuous light loss integrates two functions of STED imaging and two-photon imaging, so as to provide a powerful tool for cutting-edge biomedical research.
    Type: Application
    Filed: November 27, 2018
    Publication date: February 11, 2021
    Inventors: Yunhai Zhang, Yuguo Tang, Tongda Wei, Jian Chang, Haomin Yang, Lin Ji
  • Publication number: 20210026122
    Abstract: Disclosed is a STED super-resolution microscope capable of quick beam combination, which includes a STED imaging unit and a beam combination test unit. The excitation light and the depletion light are accurately combined by the beam combination test unit, so that the imaging light spots of the two light beams passing through the STED imaging unit can accurately coincide with each other, thereby obtaining a better super-resolution imaging effect.
    Type: Application
    Filed: October 12, 2020
    Publication date: January 28, 2021
    Inventors: Yuguo Tang, Yunhai Zhang, Tongda Wei, Jian Chang, Haomin Yang, Lin Ji
  • Publication number: 20200412198
    Abstract: An electric motor having a frame, a rotor assembly, and a stator assembly. The rotor assembly has a magnet, a bearing assembly, an impeller, and a shaft. The bearing assembly has a first bearing, a second bearing, and a biasing element between the first and second bearings. The first bearing is mounted to the frame by an o-ring, and the second bearing is mounted to the frame by adhesive.
    Type: Application
    Filed: February 19, 2019
    Publication date: December 31, 2020
    Applicant: Dyson Technology Limited
    Inventors: Nigel Youatt DYMOND, Lin JI, Kevin GARCIA
  • Publication number: 20200038480
    Abstract: A method of treating a subject having a cancer comprising administering a tumor suppressor therapy, such as a TUSC2 therapy, in conjunction with an immune checkpoint inhibitor. Kits and reagents for use in cancer therapy are also provided.
    Type: Application
    Filed: October 12, 2017
    Publication date: February 6, 2020
    Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Jack A. ROTH, Lin JI
  • Patent number: 9944951
    Abstract: Tumor suppressor genes play a major role in the pathogenesis of human lung cancer and other cancers. Cytogenetic and allelotyping studies of fresh tumor and tumor-derived cell lines showed that cytogenetic changes and allele loss on the short arm of chromosome 3 (3p) are most frequently involved in about 90% of small cell lung cancers and greater than 50% of non-small cell lung cancers. A group of recessive oncogenes, Fus1, 101F6, Gene 21 (NPRL2), Gene 26 (CACNA2D2), Luca 1 (HYAL1), Luca 2 (HYAL2), PL6, 123F2 (RaSSFI), SEM A3 and Beta* (BLU), as defined by homozygous deletions in lung cancers, have been located and isolated at 3p21.3.
    Type: Grant
    Filed: May 24, 2011
    Date of Patent: April 17, 2018
    Assignees: Board of Regents, The University of Texas System, The United States of America as represented by the Secretary of the Department of Health and Human Services
    Inventors: Lin Ji, John Dorrance Minna, Jack Roth, Michael Lerman
  • Publication number: 20140359952
    Abstract: A method of manufacturing a footwear sole includes providing a base sole, and performing an electrostatic flocking process to bond a leather material layer onto a portion of the base sole. The electrostatic flocking process includes the steps of applying an adhesive material to cover a surface of the base sole, providing a leather flock source, spraying electrically charged leather flock onto the adhesive covered surface of the base sole, and curing the base sole to bond the leather flock to the surface of the base sole. The method is described principally with respect to applying a leather material layer to a surface of a base sole, and the method may be employed to apply a leather material layer to shoe portions other than a surface of the base sole, such as a surface of the outer sole, insole, or inner sole, or a surface of a whole shoe.
    Type: Application
    Filed: June 3, 2014
    Publication date: December 11, 2014
    Applicant: Grand Fashion Trading LTD
    Inventor: Lin Ji HONG
  • Patent number: 8859727
    Abstract: A nanoparticle-polypeptide complex comprising a bioactive polypeptide in association with a nanoparticle, wherein the bioactive polypeptide is modified by the addition of a chemical moiety that facilitates cellular uptake of the protein. The polypeptide can be a protein or a peptide. In some embodiments, the amino acid sequence of the protein or peptide is derived from the amino acid sequence of a tumor suppressor gene product.
    Type: Grant
    Filed: December 19, 2012
    Date of Patent: October 14, 2014
    Assignee: The Board of Regents of the University of Texas System
    Inventors: Jacki Lin, Ralph Arlinghaus, Tong Sun, Lin Ji, Bulent Ozpolat, Gabriel Lopez-Berestein, Jack A. Roth
  • Publication number: 20130266634
    Abstract: A nanoparticle-polypeptide complex comprising a bioactive polypeptide in association with a nanoparticle, wherein the bioactive polypeptide is modified by the addition of a chemical moiety that facilitates cellular uptake of the protein. The polypeptide can be a protein or a peptide. In some embodiments, the amino acid sequence of the protein or peptide is derived from the amino acid sequence of a tumor suppressor gene product.
    Type: Application
    Filed: December 19, 2012
    Publication date: October 10, 2013
    Inventors: Jacki LIN, Ralph ARLINGHAUS, Tong SUN, Lin JI, Bulent OZPOLAT, Gabriel LOPEZ-BERESTEIN, Jack A. ROTH
  • Patent number: 8338366
    Abstract: A nanoparticle-polypeptide complex comprising a bioactive polypeptide in association with a nanoparticle, wherein the bioactive polypeptide is modified by the addition of a chemical moiety that facilitates cellular uptake of the protein. The polypeptide can be a protein or a peptide. In some embodiments, the amino acid sequence of the protein or peptide is derived from the amino acid sequence of a tumor suppressor gene product.
    Type: Grant
    Filed: March 14, 2006
    Date of Patent: December 25, 2012
    Assignee: The Board of Regents of the University of the Texas System
    Inventors: Jacki Lin, Ralph B. Arlinghaus, Tong Sun, Lin Ji, Bulent Ozpolat, Gabriel Lopez-Berestein, Jack A. Roth
  • Patent number: 8306025
    Abstract: A method for implementing the subscriber port positioning by broadband access equipments, includes: when the subscriber initiates an access request, the multi-port terminal equipment captures the access request message, adds the subscriber basic information into the access request message, and transmits it to the office equipment; the single-port terminal equipment forwards the access request message to the office equipment directly; the office equipment captures the access request message, adds the terminal basic information into the access request message and forwards it to the broadband access server; for the multi-port terminal equipment, the terminal basic information and the subscriber basic information comprises the subscriber port positioning information; for the single-port terminal equipment, the terminal basic information is taken as the subscriber port positioning information; after the broadband access server receives the access request message, it extracts the subscriber port positioning informa
    Type: Grant
    Filed: December 12, 2007
    Date of Patent: November 6, 2012
    Assignee: ZTE Corporation
    Inventors: Lin Ji, Liquan Yuan, Huannan Ma
  • Publication number: 20120108880
    Abstract: Tumor suppressor genes play a major role in the pathogenesis of human lung cancer and other cancers. Cytogenetic and allelotyping studies of fresh tumor and tumor-derived cell lines showed that cytogenetic changes and allele loss on the short arm of chromosome 3 (3p) are most frequently involved in about 90% of small cell lung cancers and greater than 50% of non-small cell lung cancers. A group of recessive oncogenes, Fus1, 101F6, Gene 21 (NPRL2), Gene 26 (CACNA2D2), Luca 1 (HYAL1), Luca 2 (HYAL2), PL6, 123F2 (RaSSFI), SEM A3 and Beta* (BLU), as defined by homozygous deletions in lung cancers, have been located and isolated at 3p21.3.
    Type: Application
    Filed: January 9, 2012
    Publication date: May 3, 2012
    Inventors: Lin Ji, John Minna, Jack Roth, Michael Lerman
  • Publication number: 20120076851
    Abstract: Tumor suppressor genes play a major role in the pathogenesis of human lung cancer and other cancers. Cytogenetic and allelotyping studies of fresh tumor and tumor-derived cell lines showed that cytogenetic changes and allele loss on the short arm of chromosome 3 (3p) are most frequently involved in about 90% of small cell lung cancers and greater than 50% of non-small cell lung cancers. A group of recessive oncogenes, Fus1, 101F6, Gene 21 (NPRL2), Gene 26 (CACNA2D2), Luca 1 (HYAL1), Luca 2 (HYAL2), PL6, 123F2 (RaSSFI), SEM A3 and Beta* (BLU), as defined by homozygous deletions in lung cancers, have been located and isolated at 3p21.3.
    Type: Application
    Filed: May 24, 2011
    Publication date: March 29, 2012
    Inventors: Lin Ji, John Dorrance Minna, Jack Roth, Michael Lerman
  • Patent number: 8063184
    Abstract: The present invention provides novel cleavage agents and polymerases for the cleavage and modification of nucleic acid. The cleavage agents and polymerases find use, for example, for the detection and characterization of nucleic acid sequences and variations in nucleic acid sequences. In some embodiments, the 5? nuclease activity of a variety of enzymes is used to cleave a target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof.
    Type: Grant
    Filed: October 5, 2010
    Date of Patent: November 22, 2011
    Assignee: Third Wave Technologies, Inc.
    Inventors: Hatim Allawi, Brad T. Argue, Christian Tor Bartholomay, LuAnne Chehak, Michelle L. Curtis, Peggy S. Eis, Jeff G. Hall, Hon S. Ip, Lin Ji, Michael Kaiser, Robert W. Kwiatkowski, Jr., Andrew A. Lukowiak, Victor Lyamichev, Natalie E. Lyamicheva, WuPo Ma, Bruce P. Neri, Sarah M. Olson, Marilyn C. Olson-Munoz, James J. Schaefer, Zbigniev Skrzypczynski, Tsetska Y. Takova, Lisa C. Thompson, Kevin L. Vedvik
  • Patent number: 7977468
    Abstract: Tumor suppressor genes play a major role in the pathogenesis of human lung cancer and other cancers. Cytogenetic and allelotyping studies of fresh tumor and tumor-derived cell lines showed that cytogenetic changes and allele loss on the short arm of chromosome 3 (3p) are most frequently involved in about 90% of small cell lung cancers and greater than 50% of non-small cell lung cancers. A group of recessive oncogenes, Fus1, 101F6, Gene 21 (NPRL2), Gene 26 (CACNA2D2), Luca 1 (HYAL1), Luca 2 (HYAL2), PL6, 123F2 (RaSSFI), SEM A3 and Beta* (BLU), as defined by homozygous deletions in lung cancers, have been located and isolated at 3p21.3.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: July 12, 2011
    Assignees: Board of Regents of the University of Texas System, The United States of America as represented by the Department of Health and Human Services
    Inventors: Lin Ji, John Dorrance Minna, Jack Roth, Michael Lerman
  • Publication number: 20110129221
    Abstract: A method for implementing the subscriber port positioning by broadband access equipments, includes: when the subscriber initiates an access request, the multi-port terminal equipment captures the access request message, adds the subscriber basic information into the access request message, and transmits it to the office equipment; the single-port terminal equipment forwards the access request message to the office equipment directly; the office equipment captures the access request message, adds the terminal basic information into the access request message and forwards it to the broadband access server; for the multi-port terminal equipment, the terminal basic information and the subscriber basic information comprises the subscriber port positioning information; for the single-port terminal equipment, the terminal basic information is taken as the subscriber port positioning information; after the broadband access server receives the access request message, it extracts the subscriber port positioning informa
    Type: Application
    Filed: December 12, 2007
    Publication date: June 2, 2011
    Applicant: ZTE Corporation
    Inventors: Lin JI, Liquan Yuan, Huannan Ma
  • Publication number: 20110104682
    Abstract: The present invention provides novel cleavage agents and polymerases for the cleavage and modification of nucleic acid. The cleavage agents and polymerases find use, for example, for the detection and characterization of nucleic acid sequences and variations in nucleic acid sequences. In some embodiments, the 5? nuclease activity of a variety of enzymes is used to cleave a target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof.
    Type: Application
    Filed: October 5, 2010
    Publication date: May 5, 2011
    Applicant: THIRD WAVE TECHNOLOGIES, INC.
    Inventors: Hatim Allawi, Brad T. Argue, Christian Tor Bartholomay, LuAnne Chehak, Michelle L. Curtis, Peggy S. Eis, Jeff G. Hall, Hon S. Ip, Lin Ji, Michael Kaiser, Robert W. Kwiatkowski, JR., Andrew A. Lukowiak, Victor Lyamichev, Natalie E. Lyamicheva, WuPo Ma, Bruce P. Neri, Sarah M. Olson, Marilyn C. Olson-Munoz, James J. Schaefer, Zbigniev Skrzypczynski, Tsetska Y. Takova, Lisa C. Thompson, Kevin L. Vedvik
  • Patent number: 7935800
    Abstract: The present invention provides novel cleavage agents and polymerases for the cleavage and modification of nucleic acid. The cleavage agents and polymerases find use, for example, for the detection and characterization of nucleic acid sequences and variations in nucleic acid sequences. In some embodiments, the 5? nuclease activity of a variety of enzymes is used to cleave a target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof.
    Type: Grant
    Filed: December 19, 2006
    Date of Patent: May 3, 2011
    Assignee: Third Wave Technologies, Inc.
    Inventors: Hatim T. Allawi, Brad T. Argue, Christian Tor Bartholomay, LuAnne Chehak, Michelle L. Curtis, Peggy S. Eis, Jeff G. Hall, Hon S. Ip, Lin Ji, Michael W. Kaiser, Robert W. Kwiatkowski, Andrew A. Lukowiak, Victor Lyamichev, Natalie E. Lyamicheva, WuPo Ma, Bruce P. Neri, Sarah M. Olson, Marilyn C. Olson-Munoz, James J. Schaefer, Zbigniev Skrzypczynski, Tsetska Y Takova, Lisa C. Thompson, Kevin L. Vedvik
  • Patent number: 7902441
    Abstract: Tumor suppressor genes play a major role in the pathogenesis of human lung cancer and other cancers. Cytogenetic and allelotyping studies of fresh tumor and tumor-derived cell lines showed that cytogenetic changes and allele loss on the short arm of chromosome 3 (3p) are most frequently involved in about 90% of small cell lung cancers and greater than 50% of non-small cell lung cancers. A group of recessive oncogenes, Fus1, 101F6, Gene 21 (NPRL2), Gene 26 (CACNA2D2), Luca 1 (HYAL1), Luca 2 (HYAL2), PL6, 123F2 (RaSSFI), SEM A3 and Beta* (BLU), as defined by homozygous deletions in lung cancers, have been located and isolated at 3p21.3.
    Type: Grant
    Filed: May 27, 2003
    Date of Patent: March 8, 2011
    Assignees: Board of Regents, The University of Texas, The United States of America as represented by the Department of Health and Human Services
    Inventors: Lin Ji, John Dorrance Minna, Jack Roth, Michael Lerman