Patents by Inventor Lin-Ju Yen

Lin-Ju Yen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD AND COMPOSITION FOR CHONDROGENESIS
    Publication number: 20220298483
    Abstract: The present application provides a composition for inducing chondrogenesis comprising an Wnt antagonist and a pharmaceutically acceptable carrier. The present application also provides a method for inducing chondrogenesis comprising administering an Wnt antagonist and a pharmaceutically acceptable carrier to a subject. The present application further provides a method for treating a cartilage-related disease comprising administering a therapeutically effective amount of an Wnt antagonist and a pharmaceutically acceptable carrier to a subject.
    Type: Application
    Filed: March 17, 2022
    Publication date: September 22, 2022
    Applicant: National Health Research Institutes
    Inventors: Lin-Ju YEN, Chen-Chan HSIEH
  • PROGENITOR CELLS, METHOD FOR PREPARATION THEREOF AND USES THEREOF
    Publication number: 20170247660
    Abstract: The present application provides progenitor cells and a preparing method thereof. The preparing method comprises obtaining a tissue sample containing myometrium from uterus, treating the tissue sample with collagenase, and culturing the treated tissue sample to obtain the progenitor cells, wherein the progenitor cell is multipotent and immunomodulatory. The present application also provides a method for treating a degenerative disease, an ischemic disease or a disease caused by abnormal immune response comprising administering the progenitor cells to a patient subjecting the disease.
    Type: Application
    Filed: September 16, 2015
    Publication date: August 31, 2017
    Applicant: National Health Research Institutes
    Inventors: Lin-Ju YEN, Ko-Jiunn LIU, Men-Luh YEN
  • Method for generating immunomodulatory cells, the cells prepared therefrom, and use thereof
    Patent number: 8927278
    Abstract: The present invention develops a straightforward and rapid method for generating immunomodulatory cells from peripheral mononuclear cells, comprising treating peripheral mononuclear cells with a hepatocyte growth factor (HGF) to induce differentiation of the peripheral mononuclear cells into immunomodulatory leukocytes. The present invention also provides an immunomodulatory cell prepared according to this method. The present invention further provides a method for treating a disease caused by abnormal immune response comprising administering a HGF to a patient exhibiting the disease, inducing the patient's peripheral mononuclear cells to differentiate into immunomodulatory leukocytes, and modulating the abnormal immune response.
    Type: Grant
    Filed: September 10, 2012
    Date of Patent: January 6, 2015
    Assignee: National Health Research Institutes
    Inventors: Lin-Ju Yen, Ko-Jiunn Liu, Huey-Kang Sytwu
  • METHOD FOR GENERATING IMMUNOMODULATORY CELLS, THE CELLS PREPARED THEREFROM AND USE THEREOF
    Publication number: 20140073569
    Abstract: The present invention develops a straightforward and rapid method for generating immunomodulatory cells from peripheral mononuclear cells, comprising treating peripheral mononuclear cells with a hepatocyte growth factor (HGF) to induce differentiation of the peripheral mononuclear cells into immunomodulatory leukocytes. The present invention also provides an immunomodulatory cell prepared according to this method. The present invention further provides a method for treating a disease caused by abnormal immune response comprising administering a HGF to a patient exhibiting the disease, inducing the patient's peripheral mononuclear cells to differentiate into immunomodulatory leukocytes, and modulating the abnormal immune response.
    Type: Application
    Filed: September 10, 2012
    Publication date: March 13, 2014
    Applicant: National Health Research Institutes
    Inventors: Lin-Ju Yen, Ko-Jiunn Liu, Huey-Kang Sytwu
  • Placental stem cell and methods thereof
    Patent number: 7534606
    Abstract: The present invention describes stem cells obtained from post-partum placenta and their methods of obtaining and culturing. The present invention also describes compositions comprising placental stem cells and methods of using placental stem cells.
    Type: Grant
    Filed: August 11, 2005
    Date of Patent: May 19, 2009
    Assignee: National Health Research Institutes
    Inventors: Yao-Chang Chen, Lin-Ju Yen, Chih-Cheng Chien, Hsing-I Huang
  • Placental stem cell and methods thereof
    Publication number: 20060030039
    Abstract: The present invention describes stem cells obtained from post-partum placenta and their methods of obtaining and culturing. The present invention also describes compositions comprising placental stem cells and methods of using placental stem cells.
    Type: Application
    Filed: August 11, 2005
    Publication date: February 9, 2006
    Inventors: Yao-Chang Chen, Lin-Ju Yen, Chih-Cheng Chien, Hsing-I Huang
  • Placental stem cell and methods thereof
    Publication number: 20050176139
    Abstract: The present invention describes stem cells obtained from post-partum placenta and their methods of obtaining and culturing. The present invention also describes compositions comprising placental stem cells and methods of using placental stem cells.
    Type: Application
    Filed: January 11, 2005
    Publication date: August 11, 2005
    Inventors: Yao-Chang Chen, Lin-Ju Yen, Chih-Cheng Chien, Hsing-I Huang