Abstract: A processor-implemented method including setting first search ranges of hyperparameters of a set of hyperparameters, performing a first training process using parameter value sets of the hyperparameters selected from the first search ranges to generate artificial intelligence (AI) models, generating evaluation scores of the AI models with respect to an evaluation indicator, determining a contribution of the hyperparameters to the evaluation scores, setting second search ranges of the hyperparameters based on the contribution of the hyperparameters, and performing a second training process based on the second search ranges.

Abstract: Provided herein are proteins comprising an anti-CD26 antigen-binding domain. Also provided herein are methods of treating an aging-related disease or an inflammatory disease in a subject that include administering to the subject one of these proteins or a cell expressing one of these proteins.

Abstract: The invention features multi-specific fusion protein complexes with one domain comprising IL-15 or a functional variant and a binding domain specific to IL-12 or IL-18.

Abstract: The invention features multi-specific fusion protein complexes with one domain comprising IL-15 or a functional variant and a binding domain specific to IL-12 or IL-18.

Abstract: The invention features multi-specific fusion protein complexes with one domain comprising IL-15 or a functional variant and a binding domain specific to IL-12 or IL-18.

Abstract: The invention features multi-specific fusion protein complexes with one domain comprising IL-15 or a functional variant and a binding domain specific to IL-12 or IL-18.

Abstract: The invention features multi-specific fusion protein complexes with one domain comprising IL-15 or a functional variant and a binding domain specific to IL-12 or IL-18.

Abstract: The invention features multi-specific fusion protein complexes with one domain comprising IL-15 or a functional variant and a binding domain specific to IL-12 or IL-18.

Abstract: The invention features multi-specific fusion protein complexes with one domain comprising IL-15 or a functional variant and a binding domain specific to IL-12 or IL-18.

Abstract: The invention features multi-specific fusion protein complexes with one domain comprising IL-15 or a functional variant and a binding domain specific to IL-12 or IL-18.

Abstract: Provided herein are proteins comprising an anti-CD26 antigen-binding domain. Also provided herein are methods of treating an aging-related disease or an inflammatory disease in a subject that include administering to the subject one of these proteins or a cell expressing one of these proteins.

Abstract: The invention provides an adaptive manifold probability distribution-based bearing fault diagnosis method, including constructing transferable domains and transfer tasks; converting a data sample in each transfer task into frequency domain data via Fourier transform, inputting the frequency domain data into a GFK algorithm model, and calculating a manifold feature representation matrix related to a bearing fault in each transfer task by using the GFK algorithm model; calculating a cosine distance between centers of a target domain and a source domain in each transfer task according to a manifold feature representation, and defining a target function of in-domain classifier learning; then solving the target function, to obtain a probability distribution matrix of the target domain; and selecting a label corresponding to the largest probability value corresponding to each data sample in the target domain from the probability distribution matrix as a predicted label of the data sample in the target domain.

Abstract: The invention features multi-specific fusion protein complexes with one domain comprising IL-15 or a functional variant and a binding domain specific to IL-12 or IL-18.

Abstract: The invention features multi-specific fusion protein complexes with one domain comprising IL-15 or a functional variant and a binding domain specific to IL-12 or IL-18.

Abstract: The invention features multi-specific fusion protein complexes with one domain comprising IL-15 or a functional variant and a binding domain specific to IL-12 or IL-18.

Abstract: The invention provides an adaptive manifold probability distribution-based bearing fault diagnosis method, including constructing transferable domains and transfer tasks; converting a data sample in each transfer task into frequency domain data via Fourier transform, inputting the frequency domain data into a GFK algorithm model, and calculating a manifold feature representation matrix related to a bearing fault in each transfer task by using the GFK algorithm model; calculating a cosine distance between centers of a target domain and a source domain in each transfer task according to a manifold feature representation, and defining a target function of in-domain classifier learning; then solving the target function, to obtain a probability distribution matrix of the target domain; and selecting a label corresponding to the largest probability value corresponding to each data sample in the target domain from the probability distribution matrix as a predicted label of the data sample in the target domain.

Abstract: The invention features multi-specific fusion protein complexes with one domain comprising IL-15 or a functional variant and a binding domain specific to IL-12 or IL-18.

Abstract: The invention features multi-specific fusion protein complexes with one domain comprising IL-15 or a functional variant and a binding domain specific to IL-12 or IL-18.

Abstract: The invention features multi-specific fusion protein complexes with one domain comprising IL-15 or a functional variant and a binding domain specific to IL-12 or IL-18.