Abstract: Systems, methods, and instrumentalities are disclosed herein associated with physical random access, e.g., for new radio (NR) implementations such as NR-unlicensed (NR-U). A wireless transmit/receive unit (WTRU) may switch a position of a PRACH occasion (RO) with another RO to reduce latency (e.g., so that a WTRU can transmit a preamble without performing a LBT operation). Systems, methods, and instrumentalities are disclosed for reserving a listen-before-talk (LBT) procedure gap at the beginning of a random access channel (RACH) occasion (RO) in New Radio (NR) unlicensed (NR-U) systems. The present systems, methods, and instrumentalities may (e.g., may also) be applied to consecutive ROs. This may include reserving a LBT gap for example, for a RO transmission (e.g., for each of the consecutive ROs). Low latency RACH for NR-U systems may be supported (e.g., mapping rules for the RO may be implemented).

Abstract: A method of feedback in a wireless transmit receive unit includes providing a precoding matrix index (PMI), error checking the (PMI) to produce an error check (EC) bit, coding the PMI and the EC bit and transmitting the coded PMI and EC bit.

Abstract: Transmit and/or receive beamforming may be applied to the control channel transmission/reception, e.g., in mmW access link system design. Techniques to identify candidate control channel beams and/or their location in the subframe structure may provide for efficient WTRU operation. A framework for beam formed control channel design may support varying capabilities of mBs and/or WTRUs, and/or may support time and/or spatial domain multiplexing of control channel beams. For a multi-beam system, modifications to reference signal design may discover, identify, measure, and/or decode a control channel beam. Techniques may mitigate inter-beam interference. WTRU monitoring may consider beam search space, perhaps in addition to time and/or frequency search space. Enhancements to downlink control channel may support scheduling narrow data beams. Scheduling techniques may achieve high resource utilization, e.g., perhaps when large bandwidths are available and/or WTRUs may be spatially distributed.

Abstract: Systems, methods, and instrumentalities are disclosed for interleaving coded bits. A wireless transmit/receive unit (WTRU) may generate a plurality of polar encoded bits using polar encoding. The WTRU may divide the plurality of polar encoded bits into sub-blocks of equal size in a sequential manner. The WTRU may apply sub-block wise interleaving to the sub-blocks using an interleaver pattern. The sub-blocks associated with a subset of the sub-blocks may be interleaved, and sub-blocks associated with another subset of the sub-blocks may not be interleaved. The sub-block wise interleaving may include applying interleaving across the sub-blocks without interleaving bits associated with each of the sub-blocks. The WTRU may concatenate bits from each of the interleaved sub-blocks to generate interleaved bits, and store the interleaved bits associated with the interleaved sub-blocks in a circular buffer. The WTRU may select a plurality of bits for transmission from the interleaved bits.

Abstract: Methods and apparatus for beam management are disclosed. A WTRU may include a plurality of antenna panels, each antenna panel comprising a plurality of antennas configured to transmit on directional transmit (TX) beams. The WTRU may send, to a transmission reception point (TRP), antenna panel capability information for the plurality of antenna panels and receive a reference signal (RS) configuration for configuring RS resource sets. The WTRU may send an RS transmission trigger frame identifying triggered RS resource sets from the configured RS resource sets. The WTRU may identify a set of antenna panels to be used with the triggered RS resource sets. The WTRU may determine an UL TX beam sweeping mode and an association between the triggered RS resources sets and the set of antenna panels. The WTRU may perform UL beam sweeping using the triggered RS resource sets and associated set of antenna panels.

Abstract: A wireless transmit/receive unit (WTRU) may receive a unique word-error check (UW-EC) encoded signal. A pre-decoder data check entity may check for errors based on EC bits and systematic and parity bits from the UW-EC encoded signal. If an error is not detected at the pre-decoder data check entity, data without an error may be signaled to a source decoder without channel decoding.

Abstract: Transmit and/or receive beamforming may be applied to the control channel transmission/reception, e.g., in mmW access link system design. Techniques to identify candidate control channel beams and/or their location in the subframe structure may provide for efficient WTRU operation. A framework for beam formed control channel design may support varying capabilities of mBs and/or WTRUs, and/or may support time and/or spatial domain multiplexing of control channel beams. For a multi-beam system, modifications to reference signal design may discover, identify, measure, and/or decode a control channel beam. Techniques may mitigate inter-beam interference. WTRU monitoring may consider beam search space, perhaps in addition to time and/or frequency search space. Enhancements to downlink control channel may support scheduling narrow data beams. Scheduling techniques may achieve high resource utilization, e.g., perhaps when large bandwidths are available and/or WTRUs may be spatially distributed.

Abstract: The invention relates to anti-EGF like domain multiple 6 antibody (anti-EGFL6 antibody) and cancer detection (or diagnosis) and treatment using the anti-EGFL6 antibody. The present invention creates anti-EGFL6 antibodies, particularly, a single-chain antibody fragments (scFv) and humanized antibody, which have ability in binding to EGFL6 and in inhibiting angiogenesis and cancer cell growth.

Abstract: A method includes receiving, by a question-answer system, a question in a first language and the question in a second language and predicting, by the question-answer system, a first answer to the question in the first language and a second answer to the question in the second language. The method also includes generating, by the question-answer system, a first vector representing the question in the first language and a second vector representing the question in the second language and adjusting the question-answer system based on the first and second answers and the first and second vectors such that when the question-answer system subsequently generates a third vector representing the question in the first language and a fourth vector representing the question in the second language, a distance between the third and fourth vectors is less than a distance between the first and second vectors.

Abstract: Systems, procedures, and instrumentalities are disclosed for transmissions with polar codes. A transmitting entity may determine a mother code length. The mother code length may be based on value(s), e.g., a maximum number of transmissions. The transmitting entity may determine a number of information bits to be polar encoded. The number of information bits may be larger than a number of payload bits. The transmitting entity may map the number of information bits to a number of bit channels of a polar code. The transmitting entity may polar encode the information bits in the bit channels using the determined mother code length. The transmitting entity may partition the polar encoded bits into a number of parts. The number of parts may be based on one or more values, e.g., the maximum number of transmissions. The transmitting entity may transmit bits that have been interleaved to a circular buffer.

Abstract: Methods are provided for treating a subject with a pain condition. Aspects of the methods include administering a gene therapy to the subject and/or a therapeutically effective amount of a composition that includes a gene therapy vector. Aspects of the vectors may include a nucleic acid sequence encoding a K-Cl cotransporter 2 (KCC2) polypeptide, including e.g., full-length and modified versions thereof. Methods are also provided for treating a subject by editing an endogenous KCC2 locus of the subject to encode a modified KCC2 polypeptide. Methods of detecting the presence of a pain condition are also provided, including where a pain condition detected in such methods is treated according to the methods described herein. Also provided are compositions, such as compositions including a gene therapy vector, such as a lentiviral vector, that includes a viral backbone nucleic acid comprising a sequence encoding a full-length human KCC2 polypeptide or a nucleic acid sequence encoding a modified KCC2 polypeptide.

Abstract: Systems, methods, and instrumentalities are described herein for supporting CBG-based retransmission with variable CBG size using variable length HARQ-ACK. A WTRU may receive a configuration to use a first table. The first table may be associated with a maximum number of code block groups per transport block (maxCBG/TB). The WTRU may determine a number of HARQ-ACK bits to send for code blocks. The determination may depend on whether an indication is received to switch from the first table to a second table. On a condition that the indication to switch from the first table to the second table is received, the WTRU may send a number of HARQ-ACK bits that is equal to two times the maxCBG/TB. The WTRU may receive a retransmission of a number of code blocks, wherein a code block group size depends on a sent number of HARQ-ACK bits.

Abstract: A method and apparatus for transmitting uplink control information (UCI) for Long Term Evolution-Advanced (LTE-A) using carrier aggregation is disclosed. Methods for UCI transmission in the uplink control channel, uplink shared channel or uplink data channel are disclosed. The methods include transmitting channel quality indicators (CQI), precoding matrix indicators (PMI), rank indicators (RI), hybrid automatic repeat request (HARQ) acknowledgement/non-acknowledgement (ACK/NACK), channel status reports (CQI/PMI/RI), source routing (SR) and sounding reference signals (SRS). In addition, methods for providing flexible configuration in signaling UCI, efficient resource utilization, and support for high volume UCI overhead in LTE-A are disclosed.

Abstract: A system for classifying a language sample intent by receiving a language sample including a set of features, identifying language sample features, determining a tokenization score for the language sample according to the language sample features, eliminating duplicate features according to the tokenization score, determining a term frequency (tf) according to the identified features and the tokenization score, determining an inverse document frequency (idf) according to the identified features and the tokenization score, and generating a term frequency-inverse document frequency (tf-idf) matrix for the identified features.

Abstract: Embodiments described herein provide systems and methods for reference signal configuration for multiple panels with panel-specific channel state information reference signals (CSI-RS) configurations and quasi-collocation (QCL) indication, including QCL type definition and indication for panel-specific CSI-RS configurations. Exemplary embodiments further provide multi-component precoder structure with panel specific component precoder and panel common precoder. Embodiments include: (semi)-open-loop schemes using random precoding for panel common precoder and/or panel specific precoder; panel selection/restriction with panel common precoder; MU-MIMO operation using different set of panels; and panel-wise CSI reporting.

Abstract: A method, computer system, and computer program product for multi-lingual chatlog training are provided. The embodiment may include receiving, by a processor, a plurality of data related to conversational data in multiple languages. The embodiment may also include assigning an intent label to each conversational data. The embodiment may further include assigning a language label to each conversational data. The embodiment may also include paring the plurality of the data related to the conversational data according to the intent label and the language label. The embodiment may further include training a machine learning model using a multi-lingual and multi-intent conversational data pairing. The embodiment may also include training the machine learning model using a single language and multi-intent conversational data paring.

Abstract: Systems, methods, and instrumentalities are disclosed for interleaving coded bits. A wireless transmit/receive unit (WTRU) may generate a plurality of polar encoded bits using polar encoding. The WTRU may divide the plurality of polar encoded bits into sub-blocks of equal size in a sequential manner. The WTRU may apply sub-block wise interleaving to the sub-blocks using an interleaver pattern. The sub-blocks associated with a subset of the sub-blocks may be interleaved, and sub-blocks associated with another subset of the sub-blocks may not be interleaved. The sub-block wise interleaving may include applying interleaving across the sub-blocks without interleaving bits associated with each of the sub-blocks. The WTRU may concatenate bits from each of the interleaved sub-blocks to generate interleaved bits, and store the interleaved bits associated with the interleaved sub-blocks in a circular buffer. The WTRU may select a plurality of bits for transmission from the interleaved bits.

Abstract: Systems, methods, and instrumentalities are disclosed for priority-based channel coding for control information. A wireless transmit/receive unit (WTRU) may sort control information associated with a first control information type into a first control information group and the control information associated with a second control information type into a second control information group, for example, based on respective priorities associated with the first and second control information types. The WTRU may group one or more bits of the first control information group into a first bit level control information group and a second bit level control information group based on priority. The WTRU may selectively apply a cyclic redundancy check (CRC) to the first control information group, the second control information group, the first bit level control information group, and/or the second bit level control information group.

Abstract: A method and apparatus for performing autonomous transmission for performing collision mitigation and complexity reduction for non-orthogonal multiple access (NOMA) transmissions are disclosed. A wireless transmit/receive unit (WTRU) may receive a configuration with multiple SRs and associated preamble subsets, randomly select a preamble subset and select a SR configuration according to the randomly selected preamble subset based on the received configuration. The WTRU may transmit an SR associated with the selected preamble subset. Next the WTRU may select a preamble from the selected preamble subset, and transmit the selected preamble with a data transmission. Each SR associated with preamble subsets may be distinguished by time and frequency resources, sequence index value, or PUCCH index value.

Abstract: This disclosure is related to aromatic compounds of formula (I), and methods of their use in treating medical conditions associated with Heat Shock Protein-90 (HSP90), e.g., cancer. Compounds of formula (I) have the following structure: Also disclosed are pharmaceutical compositions comprising compounds of formula (I).