Patents by Inventor Lin X. Ji

Lin X. Ji has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • hTMC promoter and vectors for the tumor-selective and high-efficient expression of cancer therapeutic genes
    Patent number: 8658778
    Abstract: Promoters that include a tissue-selective promoter sequence and a second promoter sequence operatively coupled to the tissue-selective promoter sequence, wherein the second promoter sequence includes a minimal viral promoter sequence, are disclosed. Nucleic acids and compositions that include these promoter sequences are also disclosed. Also disclosed are methods of improving the function of a tissue-selective promoter, involving operatively coupling a tissue-selective promoter sequence with a second promoter sequence that includes a minimal viral promoter sequence. Also disclosed are methods of delivering a gene into a cell, methods of treating a subject with a hyperproliferative disease, and methods of imaging a cell that involve use of the novel promoter sequences set forth herein.
    Type: Grant
    Filed: March 9, 2006
    Date of Patent: February 25, 2014
    Assignee: Board of Regents, The University of Texas System
    Inventors: Lin X. Ji, Bingliang Fang, Jack A. Roth