Abstract: A lacosamide pharmaceutical composition as well as a preparation method and application thereof are provided. According to the lacosamide pharmaceutical composition, lacosamide or a pharmaceutically acceptable salt thereof can be dissolved out at the same time, wherein the dissolution rate of the lacosamide pharmaceutical composition is not more than 40% within 1 hour, the dissolution rate of the lacosamide pharmaceutical composition is 20-70% within 6 hours, and the dissolution rate of the lacosamide pharmaceutical composition is not less than 65% within 24 hours. The lacosamide pharmaceutical composition has good slow release performance, the tablet size can be rapidly expanded in the in-vitro dissolution process, the expanded lacosamide pharmaceutical composition has good rigidity and elasticity and has a remarkable retention effect in the stomach, and the cumulative release rate within 24 hours can reach 80% or above.

Abstract: Provided in the present invention is a pharmaceutical composition of a small molecular GLP-1R receptor agonist suitable for oral administration. More specifically, the present invention relates to a pharmaceutical composition containing (S)-2-(3S,8S)-3-(4-(3,4-dichlorobenzyloxy)phenyl-7-((S)-1-phenylpropyl)-2,3,6,7,8,9-hexahydro-[1,4]-dioxino[2,3-g]isoquinoline-8-ylformylamino)-3-(4-(2,3-dimethylpyridin-4-yl)phenyl)propanoic acid (“OAD2”) and a pharmaceutically acceptable salt thereof, and a preparation method therefor. The composition may contain a low level of one or more oxidative degradation substances or may contain a low level of reactive oxygen species. The pharmaceutical composition provided in the present invention has low content of oxidative degradation impurity B and a low total impurity content, so that the composition can be stably stored for 12 months or more under normal temperature and normal humidity.

Abstract: A brivaracetam pharmaceutical composition contains an active pharmaceutical ingredient, a matrix forming agent, and a swelling agent. It has a sustained release effect and has a more flat release curve compared with a common gel skeleton sustained-release preparation, and thus achieves the purposes of reducing the release rate of the medicament, controlling the in vivo effective dosage of the medicament, stabilizing the blood concentration, reducing toxic and side effects and reducing the times of daily administration.

Abstract: The present disclosure relates to a pixel array and manufacturing method therefor. The method includes providing a bare wafer including a complementary metal oxide semiconductor, providing a native substrate, forming pixel structures arranged at intervals on the native substrate, forming a bonding isolation layer with multi-layer structure. The bonding isolation layer is located between adjacent pixel structures distributed along a first direction and covers the exposed surfaces of the pixel structures to obtain a light-emitting chip. The light-emitting chip includes at least one of the pixel structures distributed along the first direction or a second direction. The first direction is parallel to a top surface of the native substrate, and the second direction is perpendicular to the top surface of the native substrate. The pixel structures of a plurality of the light-emitting chips are bonded to the bare wafer, with top surfaces of the light-emitting chips facing the bare wafer.

Abstract: An epitaxial wafer structure, an epitaxial function device, and manufacturing methods thereof are provided in the present disclosure. The epitaxial wafer structure is configured to be bonded to a driver substrate provided with a plurality of driver units including a plurality of non-defective driver units and a plurality of defective driver units. The epitaxial wafer structure includes a carrier substrate, a plurality of functional units disposed on the carrier substrate, and a plurality of placeholder units disposed on the carrier substrate. Each of the plurality of functional units on the carrier substrate is corresponding in position to one of the plurality of non-defective driver units on the driver substrate. Each of the plurality of placeholder units on the carrier substrate is corresponding in position to one of the plurality of defective driver units on the driver substrate.

Abstract: A lacosamide pharmaceutical composition as well as a preparation method and application thereof are provided. According to the lacosamide pharmaceutical composition, lacosamide or a pharmaceutically acceptable salt thereof can be dissolved out at the same time, wherein the dissolution rate of the lacosamide pharmaceutical composition is not more than 40% within 1 hour, the dissolution rate of the lacosamide pharmaceutical composition is 20-70% within 6 hours, and the dissolution rate of the lacosamide pharmaceutical composition is not less than 65% within 24 hours. The lacosamide pharmaceutical composition has good slow release performance, the tablet size can be rapidly expanded in the in-vitro dissolution process, the expanded lacosamide pharmaceutical composition has good rigidity and elasticity and has a remarkable retention effect in the stomach, and the cumulative release rate within 24 hours can reach 80% or above.

Abstract: A brivaracetam pharmaceutical composition contains an active pharmaceutical ingredient, a matrix forming agent, and a swelling agent. It has a sustained release effect and has a more flat release curve compared with a common gel skeleton sustained-release preparation, and thus achieves the purposes of reducing the release rate of the medicament, controlling the in vivo effective dosage of the medicament, stabilizing the blood concentration, reducing toxic and side effects and reducing the times of daily administration.

Abstract: The present disclosure relates to a personal safety assurance system and a safety monitoring method. A smart band includes a detection module, a main chip, a band emergency button, and a wireless band connection module. The smart band transmits detected heart rate, blood pressure, and pulse of a human body to a safety monitoring application (APP). The band emergency button is configured to receive first emergency alarm information, and transmit the first emergency alarm information to the main chip. The main chip is further configured to transmit the first emergency alarm information to the safety monitoring APP through the wireless band connection module. The safety monitoring APP is configured to display the heart rate, the blood pressure, and the pulse, transmit a physical abnormality alarm signal to a hospital alarm platform, and transmit the first emergency alarm information to a public security alarm platform.

Abstract: Provided is a method for manufacturing a medical sponge for orthopedic treatment by unilateral pressing, which relates to compaction of medical sponges. The method includes a pressing machine that includes a bottom bracket, two vertical support rods, a middle support, a U-shaped support, a drive assembly and two film pressing assemblies. The two vertical support rods are fixed vertically on both ends of the bottom bracket, respectively. The middle support is fixedly arranged on a middle of an upper side of the bottom bracket, and the U-shaped support is fixedly arranged on a top of the middle support. The drive assembly is fixedly arranged on the U-shaped support. The two film pressing assemblies are fixedly arranged between two outer sides of the U-shaped support and the two vertical support rods, respectively.

Abstract: Provided is a method for manufacturing a medical sponge for orthopedic treatment by unilateral pressing, which relates to compaction of medical sponges. The method includes a pressing machine that includes a bottom bracket, two vertical support rods, a middle support, a U-shaped support, a drive assembly and two film pressing assemblies. The two vertical support rods are fixed vertically on both ends of the bottom bracket, respectively. The middle support is fixedly arranged on a middle of an upper side of the bottom bracket, and the U-shaped support is fixedly arranged on a top of the middle support. The drive assembly is fixedly arranged on the U-shaped support. The two film pressing assemblies are fixedly arranged between two outer sides of the U-shaped support and the two vertical support rods, respectively.

Abstract: An antenna of a wearable device includes a metal bottom housing of the wearable device, a printed circuit board, a metal middle housing that encircles the printed circuit board, and a communications circuit set on the printed circuit board. A slot exists between the metal middle housing and the metal bottom housing. The metal middle housing is connected to the metal bottom housing using a second connecting wire. The metal middle housing and the printed circuit board jointly serve as a ground plate. An antenna feed line is used to connect the metal bottom housing and the communications circuit module. The metal bottom housing serves as an antenna radiation body.

Abstract: The present embodiments disclose a wireless mobile device, including a metal frame, a circuit board disposed in the metal frame, where there is a slot between at least one side edge of the circuit board and the metal frame, a first grounding point is connected to the circuit board and the metal frame, a second grounding point is connected to the circuit board and the metal frame, and a feeding point is located between the first grounding point and the second grounding point and is connected to the circuit board and the metal frame; and each antenna open-circuit stub suspends in space on an outer side of the circuit board, one end is connected to the metal frame by crossing the slot, and a connection point of the antenna open-circuit stub and metal frame is located between the feeding point and the second grounding point.

Abstract: A silybin injection contains silybin, sulfobutyl ether-?-cyclodextrin, an organic solvent for injection, a pH regulator, and may further contain a co-solvent, a lyophilization bulking agent, and water for injection.

Abstract: Embodiments of the present disclosure relate to methods and terminals for improving GPS performance. One example method includes detecting a placement state of the terminal and opening a receiving channel corresponding to the placement state. The receiving channel can be used to receive signals sent by K satellites. A signal receiving channel corresponding to the terminal is selected according to the state of the terminal.

Abstract: An antenna of a wearable device includes a metal bottom housing of the wearable device, a printed circuit board, a metal middle housing that encircles the printed circuit board, and a communications circuit set on the printed circuit board. A slot exists between the metal middle housing and the metal bottom housing. The metal middle housing is connected to the metal bottom housing using a second connecting wire. The metal middle housing and the printed circuit board jointly serve as a ground plate. An antenna feed line is used to connect the metal bottom housing and the communications circuit module. The metal bottom housing serves as an antenna radiation body.

Abstract: A silybin injection contains silybin, sulfobutyl ether-?-cyclodextrin, an organic solvent for injection and may further contain a co-solvent, a lyophilization proppant, a pH regulator, water for injection and the like.

Abstract: The present embodiments disclose a wireless mobile device, including a metal frame, a circuit board disposed in the metal frame, where there is a slot between at least one side edge of the circuit board and the metal frame, a first grounding point is connected to the circuit board and the metal frame, a second grounding point is connected to the circuit board and the metal frame, and a feeding point is located between the first grounding point and the second grounding point and is connected to the circuit board and the metal frame; and each antenna open-circuit stub suspends in space on an outer side of the circuit board, one end is connected to the metal frame by crossing the slot, and a connection point of the antenna open-circuit stub and metal frame is located between the feeding point and the second grounding point.

Abstract: An antenna and a mobile terminal are disclosed that relate to the communications field. The antenna includes a ground cable and a feeder, where the feeder includes a low-frequency branch and a high-frequency branch; the low-frequency branch and the high-frequency branch have a common endpoint; the low-frequency branch is surrounded by the ground cable to form a coupled loading mode and an equivalent coupled feed loop antenna radiation mode; and the high-frequency branch is set outside the ground cable to complete a high-frequency monopole radiation mode. The mobile terminal includes a printed circuit board (PCB) and the antenna, and the antenna is printed on the PCB. An embodiment of the present invention resolves a problem of insufficient low-frequency bandwidth and insufficient high-frequency bandwidth in the prior art, effectively improves performance of the antenna, and can effectively disperse near-field energy to the PCB and the mobile terminal.

Abstract: A method, a device, and a system for coordinated multi-point transmission/reception are provided. The method includes: obtaining a reference signal received power RSRP of cells in a measurement set of a user equipment UE; determining a coordinated set of the UE according to the RSRPs; obtaining a post-processing SINR of the UE in the coordinated set and a post-processing SINR of the UE in a serving cell; determining that the post-processing SINR of the UE in the coordinated set is greater than the post-processing SINR in the serving cell; and performing coordinated multi-point transmission/reception for the UE. According to the method, the device, and the system provided by the embodiments of the present invention, an impact of an interference suppression gain on CoMP can be suppressed effectively, and the solution complexity can be reduced.

Abstract: The present disclosure relates to communication technologies and discloses a method and apparatus for multi-antenna transmitting based on spatial-frequency encoding. The method includes: performing spatial-frequency encoding on input data and outputting encoded data; mapping the encoded data to the same sub-carrier of each antenna in an antenna group; adding a phase shift to the encoded data on different sub-carriers of each antenna; OFDM-modulating the phase-shifted encoded data on each antenna; and transmitting the OFDM-modulated data by transmit antennas.