Abstract: The disclosure relates to KRASG12D inhibitor compounds having the structure of Formula (A) or Formula (B), pharmaceutical compositions thereof, and methods of use thereof for inhibiting, treating, and/or preventing KRASG12D mutation-associated diseases, disorders and conditions.

Abstract: Optoelectronic structures and methods of formation are described. In an embodiment, an optoelectronic structure includes a backplane with a driving circuitry and an array of contact pads, and a device layer bonded to the backplane. The device layer may include an array of micro-sized diodes and landing pads, and a reconstituted wiring layer including an array of via contacts connected to the array of landing pads. The reconstituted wiring layer can be directly bonded with the array of contacts with metal-metal bonds. A placement distribution of the array of landing can be decoupled from a position distribution of the array of via contacts.

Abstract: A direct tensile and acoustic testing machine under rock seepage includes a sample and a support frame. A top of the support frame is fixed with a top plate, a bearing plate is provided above the top plate, the bearing plate is provided with a plurality of vertical force transferring rods, the force transferring rods vertically penetrate through the top plate and sliding fit with the top plate, lower ends of the force transferring rods are provided with a tensile base, a top of the tensile base is provided with a lower clamp holder, a bottom of the top plate is provided with an upper clamp holder, and a clamp center of the upper clamp holder overlaps with a clamp center of the lower clamp holder. An acoustic component and a seepage component are provided in the upper clamp holder and the lower clamp holder.

Abstract: Embodiments may relate to a wavelength-division multiplexing (WDM) transceiver that has a silicon waveguide layer coupled with a silicon nitride waveguide layer. In some embodiments, the silicon waveguide layer may include a tapered portion that is coupled with the silicon nitride waveguide layer. In some embodiments, the silicon waveguide layer may be coupled with a first oxide layer with a first z-height, and the silicon nitride waveguide layer may be coupled with a second oxide layer with a second z-height that is greater than the first z-height. Other embodiments may be described or claimed.

Abstract: An electronic device may provide image light to an eye box. The display may include a light source panel that emits the image light. A waveguide may direct the image light towards the eye box. An input coupler may couple the image light into the waveguide and an output coupler may couple the image light out of the waveguide. A color filter may be optically interposed between the light source panel and the output coupler. The color filter may filter the image light using a steep cutoff characteristic. The color filter may allow the image light to exhibit a desired color point while also allowing the light source panel to use light emitters having peak emission wavelengths that maximize the efficiency of the light emitters and thus the power efficiency of the device.

Abstract: Methods and structures are described to facilitate the transfer of device layer coupons with controlled vertical position. In an embodiment, a plurality of device layer coupons is bonded to a receiving substrate with an adhesive layer, where distance between front surfaces of the plurality of device layer coupons and a bulk layer of the receiving substrate is controlled by a plurality of rigid mechanical spacers.

Abstract: Display structures and methods of operation with micro light emitting diode (LED) sidewall gating are described. In an embodiment, a display structure includes a vertically oriented micro LED mounted on a display substrate, in which the micro LED includes a p-n diode with top and bottom electrode sides, and a sidewall gate electrode spanning a sidewall of the p-n diode where the active layer is included. In various embodiments, a bias may be applied to the sidewall gate electrode while driving the micro LED to deplete a minority carrier concentration from the sidewall of the p-n diode.

Abstract: Embodiments may relate to a wavelength-division multiplexing (WDM) transceiver that has a silicon waveguide layer coupled with a silicon nitride waveguide layer. In some embodiments, the silicon waveguide layer may include a tapered portion that is coupled with the silicon nitride waveguide layer. In some embodiments, the silicon waveguide layer may be coupled with a first oxide layer with a first z-height, and the silicon nitride waveguide layer may be coupled with a second oxide layer with a second z-height that is greater than the first z-height. Other embodiments may be described or claimed.

Abstract: An apparatus and a method for measuring subcutaneous fat thickness using amplitude mode (A-mode) ultrasound technology are proposed. An echo peak generated at a fat-muscle boundary is distinguished from other echo peaks generated at muscle-bone boundaries or at muscle-muscle boundaries. The discrimination of echo peaks is based on echo time delay change when applying variable pressure to an ultrasound transducer. Statistical information of echo peak time delay change is estimated and is used for determine an echo peak generated at the fat-muscle boundary.

Abstract: An apparatus and a method for measuring subcutaneous fat thickness using amplitude mode (A-mode) ultrasound technology are proposed. An echo peak generated at a fat-muscle boundary is distinguished from other echo peaks generated at muscle-bone boundaries or at muscle-muscle boundaries. The discrimination of echo peaks is based on echo time delay change when applying variable pressure to an ultrasound transducer. Statistical information of echo peak time delay change is estimated and is used for determine an echo peak generated at the fat-muscle boundary.

Abstract: An optical circulator includes a first optical isolator including a first port and a second port and a plurality of optical isolators coupled to the second port of the first optical isolator. Each of the plurality of optical isolators comprise a first port and a second port.

Abstract: An optical circulator includes a first optical isolator including a first port and a second port and a plurality of optical isolators coupled to the second port of the first optical isolator. Each of the plurality of optical isolators comprise a first port and a second port.

Abstract: An optical circulator includes a first optical isolator including a first port and a second port and a plurality of optical isolators coupled to the second port of the first optical isolator. Each of the plurality of optical isolators comprise a first port and a second port.

Abstract: Detection of individual objects using a light source and a whispering gallery mode (WGM) resonator. Light from the whispering gallery mode (WGM) resonator is analyzed. The presence of an object is determined based on mode splitting associated with the light received by the photodetector. For example, the presence of the object may be determined based on the distance between two whispering gallery modes and/or the linewidths of the two modes in a transmission spectrum. Alternatively, the presence of the object may be determined based on a beat frequency that is determined based on a heterodyne beat signal produced by combining split laser modes in the received light from a WGM microcavity laser.

Abstract: An optical circulator includes a first optical isolator including a first port and a second port and a plurality of optical isolators coupled to the second port of the first optical isolator. Each of the plurality of optical isolators comprise a first port and a second port.

Abstract: Detection of individual objects using a light source and a whispering gallery mode (WGM) resonator. Light from the whispering gallery mode (WGM) resonator is analyzed. The presence of an object is determined based on mode splitting associated with the light received by the photodetector. For example, the presence of the object may be determined based on the distance between two whispering gallery modes and/or the linewidths of the two modes in a transmission spectrum. Alternatively, the presence of the object may be determined based on a beat frequency that is determined based on a heterodyne beat signal produced by combining split laser modes in the received light from a WGM microcavity laser.