Patents by Inventor LiNa Loo

LiNa Loo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-pembrolizumab antibodies
    Patent number: 9995753
    Abstract: The present invention provides antibodies and antigen-binding fragments thereof that bind to the antibody pembrolizumab (pembrolizumab). These antibodies are useful, for example, for use as positive controls in assays for detecting the presence of anti-drug antibodies in a sample, e.g., the blood of a patient who has been administered pembrolizumab.
    Type: Grant
    Filed: September 23, 2016
    Date of Patent: June 12, 2018
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: LiNa Loo, Shuangping Shi
  • ANTI-PEMBROLIZUMAB ANTIBODIES
    Publication number: 20170089914
    Abstract: The present invention provides antibodies and antigen-binding fragments thereof that bind to the antibody pembrolizumab (pembrolizumab). These antibodies are useful, for example, for use as positive controls in assays for detecting the presence of anti-drug antibodies in a sample, e.g., the blood of a patient who has been administered pembrolizumab.
    Type: Application
    Filed: September 23, 2016
    Publication date: March 30, 2017
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: LiNa Loo, Shuangping Shi
  • Viral nanoparticle cell-targeted delivery platform
    Patent number: 9061076
    Abstract: This invention is a process for the manufacture of a plant viral capsid to be used for the targeted delivery of therapeutics to diseased cells. The process uses a plant virus as the starting material. The choice of the plant virus overcomes a problem in the manufacture of a uniform starting material. The final product has an advantage over other plant virus-based delivery systems in that the plant virus selected has a natural structure that is resistant to breakdown during the delivery process. This system takes advantage of the reversible divalent cation switch that this capsid employs to assemble and disassemble.
    Type: Grant
    Filed: May 22, 2008
    Date of Patent: June 23, 2015
    Assignee: North Carolina State University
    Inventors: Stefan Franzen, Richard Guenther, Steven A. Lommel, LiNa Loo
  • VIRAL NANOPARTICLE CELL-TARGETED DELIVERY PLATFORM
    Publication number: 20120039799
    Abstract: This invention is a process for the manufacture of a plant viral capsid to be used for the targeted delivery of therapeutics to diseased cells. The process uses a plant virus as the starting material. The choice of the plant virus overcomes a problem in the manufacture of a uniform starting material. The final product has an advantage over other plant virus-based delivery systems in that the plant virus selected has a natural structure that is resistant to breakdown during the delivery process. This system takes advantage of the reversible divalent cation switch that this capsid employs to assemble and disassemble.
    Type: Application
    Filed: May 22, 2008
    Publication date: February 16, 2012
    Inventors: Stefan Franzen, Richard Guenther, Steven A. Lommel, LiNa Loo