Patents by Inventor Linan LIU

Linan LIU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250035557
    Abstract: Methods, apparatuses, and systems for determining a concentration of a target gas in a sample gas. An example method of preparing a replaceable testing material for detecting a target gas in a sample gas may include preparing a solution comprising a solute and a solvent, wherein the solute comprises o-tolidine; introducing a testing material substrate to the prepared solution for a period of time; and removing at least a portion of the solvent from the testing material substrate such that the testing material substrate comprises at least a portion of the o-tolidine, and thereby forming the replaceable testing material for detecting the target gas in the sample gas.
    Type: Application
    Filed: July 10, 2024
    Publication date: January 30, 2025
    Inventors: Yan YU, Chuang HUANG, Zhixiong HOU, Jiangtao LIU, Xiang HE, Yongfang HUANG, Linan ZHAO
  • Publication number: 20220241340
    Abstract: The invention provides compositions of a carrier solution to resuspend mesenchymal stem cells (MSC), methods to formulate an MSC-containing pharmaceutical composition for the treatment of medical diseases. Practicing these methods and composition will greatly preserve the cell viability, identity and biological function, and substantially slow down the cell death and function loss during preparation, storage or shipping, before the administration to a recipient.
    Type: Application
    Filed: August 6, 2020
    Publication date: August 4, 2022
    Inventors: Wenbin LIAO, Yongjun LIU, Linan LIU
  • Patent number: 10139355
    Abstract: A method for imaging three-dimensional topography with high precision, which overcomes the disadvantage and deficiency of low precision in observing three-dimensional topography of hydraulically fractured cracks of rocks, improve the precision in observing three-dimensional topography of cracks in rock hydraulic fracturing test, and benefit for scientifically understanding regular pattern of development of hydraulically fractured cracks of rocks.
    Type: Grant
    Filed: July 2, 2018
    Date of Patent: November 27, 2018
    Assignee: Institute of Geology and Geophysics, Chinese Academy of Sciences
    Inventors: Shouding Li, Linan Liu, Xiao Li, Zhongming Zhou, Zhenxing Zhang, Yanhui Liu
  • Publication number: 20180298340
    Abstract: Provided are methods for detecting and treating disease states, including cancer, diabetes, fibrosis, and autoimmune diseases, by detecting increased mechanical modulus, or stiffness, or targeting tissues having increased mechanical modulus, or stiffness. Practicing these methods provides specific and localized detection assays and therapies for these disease states. Provided are mechano-responsive cell systems that can selectively detect and treat cancer metastases by targeting the unique biophysical and mechanical properties in the tumor microenvironment. Provided are methods for making mechano-sensitive CAR T cells by using mechano-responsive promoter logic. Provided are blood tests using engineered stem cells that express reporters after the cells home to a specific niche and secrete the reporter into the blood, which can be then be detected with a blood test.
    Type: Application
    Filed: April 21, 2016
    Publication date: October 18, 2018
    Inventors: Weian ZHAO, Mark A. ECKERT, Linan LIU, Jan ZIMAK, Dongku KANG, Egest J. PONE, Shirley X. ZHANG, Mengrou LU