Patents by Inventor Linbing ZHU

Linbing ZHU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing darunavir amorphous
    Patent number: 10513527
    Abstract: The present invention relates to medical chemistry technique field, particularly relates to a preparation method for amorphous darunavir crystal, The present invention provides a preparation method for preparing amorphous form of darunavir using an anti-solvent method. It can be a different method compared to the evaporation and concentration process disclosed in WO2011048604. Although the same with WO2013114382, anti-solvent are used, the target crystal form are truly different. The crystal form of WO2013114382 is solvent-free darunavir crystal, while an amorphous form of darunavir in the present application.
    Type: Grant
    Filed: January 8, 2016
    Date of Patent: December 24, 2019
    Inventors: Jiankang Xu, Hao Wu, Meiqi Ye, Kai Ye, Linbing Zhu
  • Process for preparing darunavir amorphous
    Publication number: 20180362539
    Abstract: The present invention relates to medical chemistry technique field, particularly relates to a preparation method for amorphous darunavir crystal, The present invention provides a preparation method for preparing amorphous form of darunavir using an anti-solvent method. It can be a different method compared to the evaporation and concentration process disclosed in WO2011048604. Although the same with WO2013114382, anti-solvent are used, the target crystal form are truly different. The crystal form of WO2013114382 is solvent-free darunavir crystal, while an amorphous form of darunavir in the present application.
    Type: Application
    Filed: January 8, 2016
    Publication date: December 20, 2018
    Inventors: Jiankang XU, Hao WU, Meiqi YE, Kai YE, Linbing ZHU