Patents by Inventor Linda Gorman

Linda Gorman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polypeptides of FGF-CX
    Patent number: 7253266
    Abstract: The present invention provides FGF-CX, a novel isolated polypeptide, as well as a polynucleotide encoding FGF-CX and antibodies that immunospecifically bind to FGF-CX or any derivative, variant, mutant, or fragment of the FGF-CX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the FGF-CX polypeptide, polynucleotide and antibody are used in detection and treatment of a broad range of pathological states, as well as other uses.
    Type: Grant
    Filed: June 17, 2002
    Date of Patent: August 7, 2007
    Assignee: CuraGen Corporation
    Inventors: Richard A. Shimkets, Michael Jeffers, Sudhirdas K. Prayaga, Ferenc L. Boldog, Meijia Yang, Catherine Burgess, Elma Fernandes, John L. Herrmann, William J. LaRochelle, Henri Lichenstein, Linda Gorman, Mei Zhong, Muralidhara Padigaru, Carol E. A. Pena, John P. Alsobrook, II, Denise M. Lepley, Daniel K. Rieger, William Grosse
  • Proteins and nucleic acids encoding same
    Patent number: 7141549
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Grant
    Filed: February 8, 2005
    Date of Patent: November 28, 2006
    Inventors: Peter Mezes, Luca Rastelli, John Herrmann, John MacDougall, Haihong Zhong, Stacie Casman, Ferenc Boldog, Richard Shimkets, Linda Gorman, Andrew Eisen, Steven Spaderna, Corine Vernet, Constance Berghs, Kimberly Spytek, Vincent DiPippo, Bryan Zerhusen, John Peyman, Karen Ellerman, David Stone, William Grosse, John Alsobrook, II, Denise Lepley, Daniel Rieger, Catherine Burgess, Shlomit Edinger, Edward Voss, Charles Miller
  • Therapeutic polypeptides, nucleic acids encoding same, and methods of use
    Patent number: 7034132
    Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Grant
    Filed: June 3, 2002
    Date of Patent: April 25, 2006
    Inventors: David W. Anderson, Jason C. Baumgartner, Ferenc L. Boldog, Stacie J. Casman, Shlomit R. Edinger, Esha A. Gangolli, Valerie Gerlach, Linda Gorman, Xiaojia Guo, Tord Hjalt, Ramesh Kekuda, Li Li, John R. MacDougall, Uriel M. Malyankar, Isabelle Millet, Muralidhara Padigaru, Meera Patturajan, Carol E. A. Pena, Luca Rastelli, Richard A. Shimkets, David J. Stone, Kimberly A. Spytek, Corine A. M. Vernet, Edward Z. Voss, Bryan D. Zerhusen
  • Novel proteins and nucleic acids encoding same
    Publication number: 20060084054
    Abstract: The present invention provides novel isolated polynucleotides and small molecule target polypeptides encoded by the polynucleotides. Antibodies that immunospecifically bind to a novel small molecule target polypeptide or any derivative, variant, mutant or fragment of that polypeptide, polynucleotide or antibody are disclosed, as are methods in which the small molecule target polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states. More specifically, the present invention discloses methods of using recombinantly expressed and/or endogenously expressed proteins in various screening procedures for the purpose of identifying therapeutic antibodies and therapeutic small molecules associated with diseases. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: June 4, 2003
    Publication date: April 20, 2006
    Inventors: John Alsobrook, David Anderson, Jason Baumgartner, Constance Berghs, Ferenc Boldog, Catherine Burgess, Stacie Casman, Elina Catterton, Mohanraj Dhanabal, Shlomit Edinger, Karen Ellerman, Seth Ettenberg, Esha Gangolli, Valerie Gerlach, Linda Gorman, William Grosse, Erik Gunther, Xiaojia Guo, Vladimir Gusev, John Herrmann, Weizhen Ji, Ramesh Kekuda, Nikolai Khramtsov, William LaRochelle, Li Li, Hongping Liang, Kenneth Low, John MacDougall, Timothy Maclachlan, Uriel Malyankar, Kelly McQueeney, Amanda Mezick, Charles Miller, Isabelle Millet, Muralidhara Padigaru, Meera Patturajan, John Peyman, Xiaozhong Qian, Luca Rastelli, Daniel Rieger, Mark Rothenberg, Suresh Shenoy, Richard Shimkets, Glennda Smithson, Kimberly Spytek, David Stone, Sujatha Sukumaran, Edward Szekeres, Corine Vernet, Edward Voss, Adam Wolenc, Mei Zhong, Haihong Zhong
  • Therapeutic polypeptides, nucleic acids encoding same, and methods of use
    Publication number: 20060063200
    Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: February 2, 2005
    Publication date: March 23, 2006
    Applicant: CuraGen Corporation
    Inventors: David Anderson, Jason Baumgartner, Ferenc Boldog, Stacie Casman, Shlomit Edinger, Esha Gangolli, Valerie Gerlach, Linda Gorman, Xiaojia Guo, Tord Hjalt, Ramesh Kekuda, Li Li, John MacDougall, Uriel Malyankar, Isabelle Millet, Muralidhara Padigaru, Meera Patturajan, Carol Pena, Luca Rastelli, Richard Shimkets, David Stone, Kimberly Spytek, Corine Vernet, Edward Voss, Bryan Zerhusen
  • Proteins and nucleic acids encoding same
    Publication number: 20060013813
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: February 8, 2005
    Publication date: January 19, 2006
    Inventors: Peter Mezes, Luca Rastelli, John Herrmann, John MacDougall, Haihong Zhong, Stacie Casman, Frenc Boldog, Richard Shimkets, Linda Gorman, Andrew Eisen, Steven Spaderna, Corine Vernet, Constance Berghs, Kimberly Spytek, Vincent DiPippo, Bryan Zerhusen, John Peyman, Karen Ellerman, David Stone, William Grosse, John Alsobrook, Denise Lepley, Daniel Rieger, Catherine Burgess, Sholmit Edinger, Edward Voss, Charles Miller
  • Proteins and nucleic acids encoding same
    Publication number: 20060009634
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: December 21, 2004
    Publication date: January 12, 2006
    Inventors: Ramesh Kekuda, John Alsobrook, Velizar Tchernev, Xiaohong Liu, Kimberly Spytek, Meera Patturajan, William Grosse, Denise Lepley, Catherine Burgess, Corine Vernet, Li Li, Linda Gorman, Shlomit Edinger, Paul Sciore, Karen Ellerman, Uriel Malyankar, Mark Rothenberg, David Stone, Ferenc Boldog, Xiaojia Guo, Suresh Shenoy, David Anderson, Muralidhara Padigaru, Raymond Taupier, Charles Miller, Andrew Eisen
  • Therapeutic polypeptides, nucleic acids encoding same, and methods of use
    Publication number: 20060003323
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. Vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same are also included. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: June 3, 2003
    Publication date: January 5, 2006
    Inventors: John Alsobrook, Enrique Alvarez, David Anderson, Ferenc Boldog, Stacie Casman, Elina Catterton, Andrei Chapoval, Julie Crabtree-Bokor, Shlomit Edinger, Karen Ellerman, Seth Ettenberg, Esha Gangolli, Valerie Gerlach, Linda Gorman, Erik Gunther, Xiaojia (Sasha) Guo, Vladimir Gusev, John Herrmann, Weizhen Ji, Ramesh Kekuda, Li Li, Xiaohong Liu, John MacDougall, Timothy Machlachlan, Uriel Malyankar, Amanda Mezick, Isabelle Millet, Vishnu Mishra, Muralidhara Padigaru, Meera Patturajan, Carol Pena, John Peyman, Debasish Raha, Luca Rastelli, Daniel Rieger, Mark Rothenberg, Paul Sciore, Suresh Shenoy, Richard Shimkets, Glennda Smithson, Kimberly Spytek, David Stone, Corine Vernet, Edward Voss, Mei Zhong, Hiahong Zhong
  • Therapeutic polypeptides, nucleic acids encoding same, and methods of use
    Publication number: 20050287564
    Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: May 10, 2005
    Publication date: December 29, 2005
    Inventors: Linda Gorman, Richard Shimkets, Carol Pena, Valerie Gerlach, Kumud Majumder, Sudhirdas Prayaga, Catherine Burgess
  • Therapeutic polypeptides, nucleic acids encoding same, and methods of use
    Patent number: 6974684
    Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Grant
    Filed: August 1, 2002
    Date of Patent: December 13, 2005
    Assignee: CuraGen Corporation
    Inventors: David W. Anderson, John P. Alsobrook II, Ferenc L. Boldog, Catherine E. Burgess, Stacie J. Casman, Shlomit R. Edinger, Esha A. Gangolli, Linda Gorman, Xiaojia Sasha Guo, Nikolai Khramtsov, Denise M. Lepley, John R. MacDougall, Carol E. A. Pena, John A. Peyman, Meera Patturajan, Daniel K. Rieger, Richard A. Shimkets, Glennda Smithson, Kimberly A. Spytek, Corine A. M. Vernet, Edward Z. Voss, Mei Zhong
  • Therapeutic polypeptides, nucleic acids encoding same, and methods of use
    Publication number: 20050053930
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: June 3, 2003
    Publication date: March 10, 2005
    Inventors: David Anderson, Ferenc Boldog, Catherine Burgess, Stacie Casman, Shlomit Edinger, Andrew Eisen, Karen Ellerman, Valerie Gerlach, Linda Gorman, Xiaojia Guo, Vladimir Gusev, Weizhen Ji, Li Li, John MacDougall, Uriel Malyankar, Isabelle Millet, Tatiana Ort, Muralidhara Padigaru, Sudhirdas Prayaga, Meera Patturajan, Carol Pena, John Peyman, Daniel Rieger, Mark Rothenberg, Paul Sciore, Suresh Shenoy, Glennda Smithson, Kimberly Spytek, David Stone, Raymond Taupier, Velizar Tchernev, Corine Vernet, Edward Voss, Bryan Zerhusen, Mei Zhong
  • Therapeutic polypeptides, nucleic acids encoding same, and methods of use
    Publication number: 20050049192
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. Vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same are also included. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: August 6, 2003
    Publication date: March 3, 2005
    Inventors: Mei Zhong, Weizhen Ji, Xiaojia Guo, Daniel Rieger, Muralidhara Padigaru, Rachel Malcolm, Kimberly Spytek, David Anderson, Linda Gorman, Elina Catterton, John MacDougall, David Stone, Shlomit Edinger
  • Novel proteins and nucleic acids encoding same
    Publication number: 20050037957
    Abstract: The present invention provides novel isolated polynucleotides and small molecule target polypeptides encoded by the polynucleotides. Antibodies that immunospecifically bind to a novel small molecule target polypeptide or any derivative, variant, mutant or fragment of that polypeptide, polynucleotide or antibody are disclosed, as are methods in which the small molecule target polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states. More specifically, the present invention discloses methods of using recombinantly expressed and/or endogenously expressed proteins in various screening procedures for the purpose of identifying therapeutic antibodies and therapeutic small molecules associated with diseases. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: August 6, 2003
    Publication date: February 17, 2005
    Inventors: David Anderson, Constance Berghs, Elina Catterton, Shlomit Edinger, Linda Gorman, Xiaojia Guo, John Herrmann, Ramesh Kekuda, Li Li, Daniel Rieger, Mei Zhong
  • Therapeutic polypeptides, nucleic acids encoding same, and methods of use
    Publication number: 20040259774
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. Vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same are also included. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: February 3, 2003
    Publication date: December 23, 2004
    Inventors: Enrique Alvarez, Shlomit R. Edinger, Esha A. Gangolli, Valerie Gerlach, Linda Gorman, Xiaojia (Sasha) Guo, Weizhen Ji, Ramesh Kekuda, Li Li, Charles E. Miller, Muralidhara Padigaru, Meera Patturajan, Luca Rastelli, Daniel K. Rieger, Suresh G. Shenoy, Richard A. Shimkets, Kimberly A. Spytek, Mei Zhong
  • Compositions and methods of use for a fibroblast growth factor
    Publication number: 20040214759
    Abstract: In methods of using a fibroblast growth factor, such as for treating, preventing or delaying a proliferation-associated disorder, steps are provided to administer to a subject a therapeutically effective amount of a particular fibroblast growth factor polypeptide, or variant or fragment thereof.
    Type: Application
    Filed: May 9, 2003
    Publication date: October 28, 2004
    Inventors: John P. Alsobrook, Enrique Alvarez, David W. Anderson, Joel S. Bader, Ferenc L. Boldog, Catherine E. Burgess, Rajeev A. Chillakuru, Lisa Deegler, Shlomit R. Edinger, Elma R. Fernandes, Linda Gorman, William M. Grosse, John L. Herrmann, Michael E. Jeffers, William J. LaRochelle, Denise M. Lepley, Henri S. Lichenstein, Kumar Namdev, Muralidhara Padigaru, Carol E. A. Pena, Sudhirdas K. Prayaga, Daniel K. Rieger, Richard A. Shimkets, Pascal Valax, Meijia Yang, Zachary Yim, Mei Zhong
  • Novel proteins and nucleic acids encoding same
    Publication number: 20040086875
    Abstract: The present invention provides novel isolated polynucleotides and small molecule target polypeptides encoded by the polynucleotides. Antibodies that immunospecifically bind to a novel small molecule target polypeptide or any derivative, variant, mutant or fragment of that polypeptide, polynucleotide or antibody are disclosed, as are methods in which the small molecule target polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states. More specifically, the present invention discloses methods of using recombinantly expressed and/or endogenously expressed proteins in various screening procedures for the purpose of identifying therapeutic antibodies and therapeutic small molecules associated with diseases. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: November 4, 2002
    Publication date: May 6, 2004
    Inventors: Michele L. Agee, John P. Alsobrook, Constance Berghs, Ferenc L. Boldog, Catherine E. Burgess, John S. Chant, Amitabha Chaudhuri, Vincent A. DiPippo, Shlomit R. Edinger, Andrew Eisen, Karen Ellerman, Esha A. Gangolli, Linda Gorman, Valerie Gerlach, Weizhen Ji, Ramesh Kekuda, Nikolai V. Khramtsov, Li Li, Uriel M. Malyankar, John R. MacDougall, Peter S. Mezes, Charles E. Miller, Isabelle Millet, Chean Eng. Ooi, Tatiana Ort, Muralidhara Padigaru, Meera Patturajan, Luca Rastelli, Daniel K. Rieger, Mark E. Rothenberg, Suresh G. Shenoy, Steven K. Spaderna, Kimberly A. Spytek, Raymond J. Taupier, Corine A.M. Vernet, Bryan D. Zerhusen, Mei Zhong
  • Therapeutic polypeptides, nucleic acids encoding same, and methods of use
    Publication number: 20040072997
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. Vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same are also included. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: January 3, 2003
    Publication date: April 15, 2004
    Inventors: John P. Alsobrook, David W. Anderson, Catherine E. Burgess, Shlomit R. Edinger, Karen Ellerman, Katarzyna Furtak, Esha A. Gangolli, Valerie Gerlach, Jennifer A. Gilbert, Erik Gunther, Linda Gorman, Xiaojia (Sasha) Guo, Weizhen Ji, Li Li, Charles E. Miller, Muralidhara Padigaru, Meera Patturajan, Luca Rastelli, John R. MacDougall, Vishnu Mishra, Glennda Smithson, Kimberly A. Spytek, David J. Stone, Suresh G. Shenoy, Raymond J. Taupier, Corine A.M. Vernet, Mei Zhong, Uriel M. Malyankar, Isabelle Millet, Ramesh Kekuda, William M. Grosse
  • Therapeutic polypeptides, nucleic acids encoding same, and methods of use
    Publication number: 20040067505
    Abstract: The present invention provides novel isolated polynucleotides and small molecule target polypeptides encoded by the polynucleotides. Antibodies that immunospecifically bind to a novel small molecule target polypeptide or any derivative, variant, mutant or fragment of that polypeptide, polynucleotide or antibody are disclosed, as are methods in which the small molecule target polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states. More specifically, the present invention discloses methods of using recombinantly expressed and/or endogenously expressed proteins in various screening procedures for the purpose of identifying therapeutic antibodies and therapeutic small molecules associated with diseases. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: May 1, 2003
    Publication date: April 8, 2004
    Inventors: Enrique Alvarez, David Anderson, Ferenc Boldog, Elina Catterton, Shlomit R. Edinger, Elma Fernandes, Valerie Gerlach, Linda Gorman, William Grosse, Xiaojia (Sasha) Guo, Weizhen Ji, Ramesh Kekuda, Li Li, John R. MacDougall, Muralidhara Padigaru, Meera Patturajan, Jeffery D. Peterson, Luca Rastelli, Richard Shimkets, Kimberly Spytek, David J. Stone, Corine A.M. Vernet, Edward Voss, Mei Zhong
  • Therapeutic polypeptides, nucleic acids encoding same, and methods of use
    Publication number: 20040067490
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. Vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same are also included. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: September 6, 2002
    Publication date: April 8, 2004
    Inventors: Mei Zhong, Li Li, Linda Gorman, Kimberly A. Spytek, Ramesh Kekuda, Raymond J. Taupier, David W. Anderson, Corine A.M. Vernet, Elina Catterton, Charles E. Miller, Suresh G. Shenoy, Meera Patturajan, Carol E. A. Pena, Velizar T. Tchernev, Muralidhara Padigaru, Vladimir Y. Gusev, Uriel M. Malyankar, Catherine E. Burgess, Valerie Gerlach, Stacie J. Casman, Daniel K. Rieger, William M. Grosse, Glennda Smithson, John A. Peyman, Gary Starling, Mark E. Rothenberg, William J. LaRochelle, Richard A. Shimkets, Julie Crabtree, Luca Rastelli, Edward Z. Voss, Ferenc L. Boldog, Shlomit R. Edinger, Isabelle Millet, John R. MacDougall, Karen Ellerman, Andrei Chapoval
  • Therapeutic polypeptides, nucleic acids encoding same, and methods of use
    Publication number: 20040067882
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. Vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same are also included. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: November 5, 2002
    Publication date: April 8, 2004
    Inventors: John P. Alsobrook, Enrique Alvarez, David W. Anderson, Melanie Baron, Ferenc L. Boldog, Catherine E. Burgess, Stacie J. Casman, Andrei Chapoval, Mohanraj Dhanabal, Shlomit R. Edinger, Andrew Eisen, Karen Ellerman, Seth Ettenberg, Esha A. Gangolli, Valerie Gerlach, Linda Gorman, William M. Grosse, Xiaojia (Sasha) Guo, Craig Hackett, Weizhen Ji, Ramesh Kekuda, Nikolai V. Khramtsov, Denise M. Lepley, Li Li, John R. MacDougall, Uriel M. Malyankar, Ann Mazur, Kelly McQueeney, Peter S. Mezes, Charles E. Miller, Isabelle Millet, Vishnu Mishra, Muralidhara Padigaru, Meera Patturajan, Carol E. A. Pena, John A. Peyman, Luca Rastelli, Daniel K. Rieger, Mark E. Rothenberg, Suresh G. Shenoy, Richard A. Shimkets, Glennda Smithson, Steven K. Spaderna, Gary Starling, Kimberly A. Spytek, David J. Stone, Velizar T. Tchernev, Nancy Twomlow, Corine A.M. Vernet, Bryan D. Zerhusen, Edward Z. Voss, Mei Zhong