Patents by Inventor Linda H. Shapiro

Linda H. Shapiro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biomarker panel for non-invasive diagnosis of congenital renal dysfunction
    Patent number: 11940450
    Abstract: Disclosed herein are methods and compositions for prognosing or diagnosing an obstructive renal dysfunction or ureteropelvic junction obstruction (UPJO) in a subject, involving detecting in a urine sample from a subject one or more proteins selected from the group consisting of Immunoglobulin superfamily containing leucine-rich repeat protein (ISLR); Nicotinate-nucleotide pyrophosphorylase [carboxylating] (QPRT); Prostaglandin reductase 1 (PTGR1); Vascular cell adhesion protein 1 (VCAM1); and Ficolin-2 (FCN2), or detectable portions thereof to identify the subject as at risk of or having an obstructive renal dysfunction or UPJO.
    Type: Grant
    Filed: March 15, 2022
    Date of Patent: March 26, 2024
    Assignee: UNIVERSITY OF CONNECTICUT
    Inventors: Linda H. Shapiro, Fernando A. Ferrer, Charan Devarakonda, James J. Grady
  • Biomarker Panel for Non-Invasive Diagnosis of Congenital Renal Dysfunction
    Publication number: 20220299530
    Abstract: Disclosed herein are methods and compositions for prognosing or diagnosing an obstructive renal dysfunction or ureteropelvic junction obstruction (UPJO) in a subject, involving detecting in a urine sample from a subject one or more proteins selected from the group consisting of Immunoglobulin superfamily containing leucine-rich repeat protein (ISLR); Nicotinate-nucleotide pyrophosphorylase [carboxylating] (QPRT); Prostaglandin reductase 1 (PTGR1); Vascular cell adhesion protein 1 (VCAM1); and Ficolin-2 (FCN2), or detectable portions thereof to identify the subject as at risk of or having an obstructive renal dysfunction or UPJO.
    Type: Application
    Filed: March 15, 2022
    Publication date: September 22, 2022
    Inventors: Linda H. SHAPIRO, Fernando A. FERRER, Charan DEVARAKONDA, James J. GRADY
  • Regulating transplant rejection of donor and embryonic stem cell-derived tissues and organs
    Patent number: 9783616
    Abstract: The invention provides methods and cells for improved transplantation of donor transplants to subjects in need thereof.
    Type: Grant
    Filed: April 2, 2014
    Date of Patent: October 10, 2017
    Assignee: University of Connecticut
    Inventors: Linda H. Shapiro, Jiyeon K. Denninger
  • Regulating Transplant Rejection of Donor and Embryonic Stem Cell-Derived Tissues and Organs
    Publication number: 20160053021
    Abstract: The invention provides methods and cells for improved transplantation of donor transplants to subjects in need thereof.
    Type: Application
    Filed: April 2, 2014
    Publication date: February 25, 2016
    Inventors: Linda H. Shapiro, Jiyeon K. Denninger